Results 61 to 70 of about 23,776 (268)
Synthesis of a novel chemotype via sequential metal-catalyzed cycloisomerizations
Beilstein Journal of Organic Chemistry, 2012 Sequential cycloisomerizations of diynyl o-benzaldehyde substrates to access novel polycyclic cyclopropanes are reported. The reaction sequence involves initial Cu(I)-mediated cycloisomerization/nucleophilic addition to an isochromene followed by ...
Bo Leng +4 more
doaj +1 more source
A Chiral Saddle‐Shaped Nanographene With Two Heptagon‐Embedded [4]Helicenes
Angewandte Chemie International Edition, EarlyView.We present a novel synthetic strategy toward a chiral saddle‐shaped nanographene (cSNG) via a two‐step oxidation of a prochiral anthracene precursor. The Scholl‐type oxidation first yields a key intermediate with sp3‐defect heptagons, and subsequent oxidative dehydrogenation affords fully conjugated cSNG.
Felix Trautner +11 more
wiley +1 more source
Nature Communications, 2017 Enantioselective synthesis of six-membered oxacycles with multiple stereogenic centres is essential for the discovery of new therapeutic agents. Here the authors show organocatalytic cycloetherification for the highly enantio- and diastereoselective ...
Naoki Yoneda +4 more
doaj +1 more source
Diastereoselective β-Hydroxy Vinylsulfone Isomerizations
Vinylic phenylsulfones containing a β-hydroxyl stereocenter undergo a diastereoselective isomerization to the corresponding allylic isomer upon treatment with 1,8-diazabicyclo(5.4.0)undec-7-ene (DBU).
Henry, Crockett +5 more
core +1 more source
Highly Diastereoselective Formal Nucleophilic Substitution of Bromocyclopropanes
, 2016 Highly Diastereoselective Formal Nucleophilic Substitution of ...
Marina Rubina (1874431) +4 more
core +2 more sources
, 2019 Citation: 'diastereoselectivity' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.D01684 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire +1 more source
Lewis acid-catalyzed diastereoselective ene reaction of thioindolinones with bicyclobutanes
Bicyclo[1.1.0]butanes (BCBs), featuring two fused cyclopropane rings, have found widespread application in organic synthesis. Their versatile reactivity towards radicals, nucleophiles, cations, and carbenes makes them suitable for various reactions ...
Akkattu, Biju +2 more
core +1 more source
Highly diastereoselective dimerisation of alkenylthiazolines
, 2001 Alkenylthiazolines undergo a highly diastereoselective novel dimerisation when treated with trichloroacetyl chloride or with trifluoroacetic ...
Elliott, Mark Christopher +3 more
core +1 more source
Highly Regio- and Diastereoselective Tethered Aza-Wacker Cyclizations of Alkenyl Phosphoramidates
, 2021 We present highly diastereoselective tetheredaza-Wacker cyclization reactions of alkenyl phosphoramidates. “Arming” the phosphoramidate tether with 5-chloro-8-quinolinol was essential to achieving >20:1 diastereoselectivity in these reactions.
Anand H., Shinde +3 more
core +1 more source
An efficient synthesis of the guaiane sesquiterpene (−)-isoguaiene by domino metathesis
Beilstein Journal of Organic Chemistry, 2019 (−)-Isoguaiene was prepared from (S)-citronellal in only 9–10 steps with good overall yields. Either a trienyne or a dienediyne metathesis and highly diastereoselective organocatalytic Michael additions of aldehydes derived from (S)-citronellal served as
Yuzhou Wang +3 more
doaj +1 more source