Results 41 to 50 of about 27,841 (247)

Cobalt‐Catalyzed [2σ+2π] Cycloaddition via Site‐Selective Capture of Bicyclobutane Diradical

Angewandte Chemie, EarlyView.
We report a Co(II)‐catalyzed strategy that combines thermal activation of bicyclo[1.1.0]butane (BCBs) with site‐selective radical capture to furnish head‐to‐head fused bicyclo[2.1.1]hexanes via [2σ+2π] cycloaddition with indoles. Detailed mechanistic studies (31P NMR, EPR, CV, and DFT) support the catalytic pathway, while phosphine‐oxide trapping and X‐
Tanmayee Nanda, Alexander Umanzor, Julia Gartzke, Jeremy T. Maddigan‐Wyatt, Philipp Thielert, Stefan Weber, Sabine Richert, Shuming Chen, Daniel B. Werz   +8 more
wiley   +2 more sources

Diastereoselective Enolsilane Coupling Reactions

, 2016
Diastereoselective Enolsilane Coupling ...
Scott J. Miller (1308798), Christopher D. Bayne (3041715)   +1 more
core   +1 more source

Diastereoselective Synthesis of Iminosugars using g-Siloxyallyltins

, 2005
Communication par affiche intitulée (présentée par J.-P.
Beaudet, I., Le Grognec, E., Chevallier, J.F., Quintard, J.-P.   +3 more
core   +7 more sources

NiH‐Catalyzed Enantio‐ and Regioselective Hydroselenylation of Unactivated Alkenes

Advanced Science, EarlyView.
Nickel‐hydride‐catalyzed enantio‐ and regioselective hydroselenylation of unactivated alkenes provides access to chiral organoselenium compounds. Enantiodetermining Ni–H insertion followed by single‐electron diselenide activation generates selenyl radical.
Hyung‐Joon Kang, Jaehun Kim, Sungwoo Hong   +2 more
wiley   +1 more source

Z‐Retentive Enantioselective Rh‐Catalyzed Hydroarylation of E,Z‐Dienes

Angewandte Chemie, EarlyView.
The Rh‐catalyzed hydroarylation of conjugated E,Z‐dienoates is found to proceed with high selectivity for addition to the E‐alkene unit. Mechanistic analysis of this Z‐retentive process points towards preferred binding of the E‐alkene unit to a Rh‐aryl species to give rise to the observed selectivity and that Rh‐enolate protonolysis to be turnover ...
Wesley McNutt, Hima Kozhummal, Abdullah Al‐Mashqbeh, Alex Brown, Rylan J. Lundgren   +4 more
wiley   +2 more sources

Highly Diastereoselective Formal Nucleophilic Substitution of Bromocyclopropanes

, 2016
Highly Diastereoselective Formal Nucleophilic Substitution of ...
Marina Rubina (1874431), Bassam K. Alnasleh (2198467), Michael Rubin (1637770), Joseph Banning (2372428), William M. Sherrill (2372425)   +4 more
core   +2 more sources

Redox‐Neutral and Diastereoselective Cross‐Pinacol Coupling of Pyridyl Ketones With Amine‐Derived Aldehydes

ChemistryEurope
Controlling the cross‐selectivity and diastereoselectivity in cross‐pinacol coupling reactions remains challenging. Herein, we report a redox‐neutral strategy that enables the cross‐selective pinacol coupling between pyridyl ketones and amine‐derived ...
Takahito Kuribara, Katsuma Ando, Ayahito Kaneki, Tetsuhiro Nemoto   +3 more
doaj   +1 more source

Inherently chiral calix[4]arenes via oxazoline directed ortholithiation: synthesis and probe of chiral space

Beilstein Journal of Organic Chemistry, 2014
The diastereoselective oxazoline-directed lithiation of calix[4]arenes is reported with diastereoselective ratios of greater than 100:1 in some instances.
Simon A. Herbert, Laura J. van Laeren, Dominic C. Castell, Gareth E. Arnott   +3 more
doaj   +1 more source

Enantioselective Access to Trifluoromethylated Spirocyclopropyl Heterocycles

Advanced Science, EarlyView.
We report a rhodium‐catalyzed asymmetric [2+1] spirocyclopropanation of methylene azacycles with trifluoromethyl carbenes in situ derived from fluoroalkyl triftosylhydrazones. ABSTRACT Chiral spirocyclopropyl heterocycles have emerged as privileged three‐dimensional structural motifs in medicinal chemistry.
Yuanhao Zhu, Youzhi Xu, Weitao Zhang, Yongyue Ning, Yaojia Jiang, Yongquan Ning, Genping Huang, Jiawei Cheng, Paramasivam Sivaguru, Xihe Bi   +9 more
wiley   +1 more source

Diastereoselective Synthesis of Trisubstituted Cyclopropylstannanes

, 2016
Diastereoselective Synthesis of Trisubstituted ...
Seok-In Kim (3046293), Kwangho Lee (2105629), Jin Kun Cha (1470760)   +2 more
core   +1 more source