Results 41 to 50 of about 6,473 (220)

Synthesis of (3R,5R)-harzialactone A and its (3R,5S)-isomer

Beilstein Journal of Organic Chemistry, 2010
The total synthesis of (3R,5R)-harzialactone A (1) and its (3R,5S)-isomer (2) is described. Epoxide opening with thioacetal and diastereoselective reductions are used as key reactions.
Gowravaram Sabitha, Rangavajjula Srinivas, Sukant K. Das, Jhillu S. Yadav   +3 more
doaj   +1 more source

Diastereoselective desymmetric 1,2-cis-glycosylation of meso-diols via chirality transfer from a glycosyl donor

Nature Communications, 2020
Enzyme-catalyzed desymmetric glycosylations are often found in nature, however the corresponding chemical methods are lacking. Here, the authors report a highly diastereoselective desymmetric 1,2-cis-glycosylation of meso-diols found in myo-inositol 1,3 ...
Masamichi Tanaka, Koji Sato, Ryoki Yoshida, Nobuya Nishi, Rikuto Oyamada, Kazuki Inaba, Daisuke Takahashi, Kazunobu Toshima   +7 more
doaj   +1 more source

Stereoselective Synthesis of Euscapholide and Tetraketide via Prins Cyclisation and Ring-Closing Metathesis

SynOpen, 2022
A concise and diastereoselective total synthesis of tetraketide and euscapholide is described in ten steps in 10.6% overall yield from acetaldehyde and (S)-pent-4-ene-1,2-diol.
Dhanraj O. Biradar, Yogesh D. Mane, Basi V. Subba Reddy   +2 more
doaj   +1 more source

A diastereoselective approach to axially chiral biaryls via electrochemically enabled cyclization cascade

Beilstein Journal of Organic Chemistry, 2019
A diastereoselective approach to axially chiral imidazopyridine-containing biaryls has been developed. The reactions proceed through a radical cyclization cascade to construct the biaryls with good to excellent central-to-axial chirality transfer.
Hong Yan, Zhong-Yi Mao, Zhong-Wei Hou, Jinshuai Song, Hai-Chao Xu   +4 more
doaj   +1 more source

diastereoselectivity

, 2019
Citation: 'diastereoselectivity' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.D01684 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Synthesis of a novel chemotype via sequential metal-catalyzed cycloisomerizations

Beilstein Journal of Organic Chemistry, 2012
Sequential cycloisomerizations of diynyl o-benzaldehyde substrates to access novel polycyclic cyclopropanes are reported. The reaction sequence involves initial Cu(I)-mediated cycloisomerization/nucleophilic addition to an isochromene followed by ...
Bo Leng, Stephanie Chichetti, Shun Su, Aaron B. Beeler, John A. Porco Jr.   +4 more
doaj   +1 more source

Stereoselective gridization and polygridization with centrosymmetric molecular packing

Nature Communications, 2020
Gridarenes with well-defined edges and vertices represent versatile nanoscale building blocks for installating frameworks but suffer from lack of stereoselective control during their synthesis. Here, the authors report a diastereoselective gridization of
Dongqing Lin, Ying Wei, Aizhong Peng, He Zhang, Chunxiao Zhong, Dan Lu, Hao Zhang, Xiangping Zheng, Lei Yang, Quanyou Feng, Linghai Xie, Wei Huang   +11 more
doaj   +1 more source

Recent developments in the asymmetric Reformatsky-type reaction

Beilstein Journal of Organic Chemistry, 2018
This review collects the most important developments in asymmetric Reformatsky-type reactions published since the beginning of 2013, including both diastereoselective methodologies based on the use of chiral substrates and enantioselective catalytic ...
Hélène Pellissier
doaj   +1 more source

Catalytic Diastereoselective Petasis Reactions [PDF]

Angewandte Chemie, 2011
Multicomponent Petasis reactions: the first diastereoselective Petasis reaction catalyzed by chiral biphenols that enables the synthesis of syn and anti β-amino alcohols in pure form has been developed. The reaction exploits a multicomponent approach that involves boronates, α-hydroxy aldehydes, and amines.
Giovanni, Muncipinto, Philip N, Moquist, Stuart L, Schreiber, Scott E, Schaus   +3 more
openaire   +2 more sources

Organocatalytic enantio- and diastereoselective cycloetherification via dynamic kinetic resolution of chiral cyanohydrins

Nature Communications, 2017
Enantioselective synthesis of six-membered oxacycles with multiple stereogenic centres is essential for the discovery of new therapeutic agents. Here the authors show organocatalytic cycloetherification for the highly enantio- and diastereoselective ...
Naoki Yoneda, Yuki Fujii, Akira Matsumoto, Keisuke Asano, Seijiro Matsubara   +4 more
doaj   +1 more source