Results 21 to 30 of about 26,606 (255)

Synthesis and properties of new chiral heterocyclic peptide mimetics [PDF]

, 2008
The synthesis of tetrahydrofuran C(alpha)-tetrasubstituted amino acids (TAAs) and their effect on the conformation in small peptides are reported. The synthesis starts from the protein amino acid methionine, which is protected at the C and N terminus and
Maity, Prantik
core   +1 more source

Titanium-Catalyzed Diastereoselective Keto- and Iminonitrile Cyclizations. [PDF]

Chemistry
The titanium(III)‐catalyzed diastereoselective cyclization of readily‐available substituted ketonitriles gives cyclopentanones in good yield and stereoselectivity. Subsequent 1,2‐addition allows the preparation of cyclopentyls with three consecutive stereocenters.
Kern C, Singh R, Unkrig-Bau MA, Jakob L, Streuff J.   +4 more
europepmc   +2 more sources

Enantio- and Diastereoselective Suzuki-Miyaura Coupling with Racemic Bicycles [PDF]

, 2019
Herein we describe a rhodium-catalyzed enantio- and diastereoselective Suzuki-Miyaura cross-coupling between racemic fused bicyclic allylic chlorides and boronic acids.
Friedrich Wieland, Goetzke, Stephen P., Fletcher, Mike, Mortimore   +2 more
core   +2 more sources

Diastereoselective synthesis of new O-alkylated and C-branched inositols and their corresponding fluoro analogues

Beilstein Journal of Organic Chemistry, 2016
Efficient routes were developed for the diastereoselective synthesis of new O-alkylated and C-branched inositols and their corresponding fluoro analogues.
Charlotte Collet, Françoise Chrétien, Yves Chapleur, Sandrine Lamandé-Langle   +3 more
doaj   +1 more source

Chiral Syn-1,3-diol Derivatives via a One-Pot Diastereoselective Carboxylation/ Bromocyclization of Homoallylic Alcohols

iScience, 2018
Summary: Chiral syn-1,3-diols are fundamental structural motifs in many natural products and drugs. The traditional Narasaka-Prasad diastereoselective reduction from chiral β-hydroxyketones is an important process for the synthesis of these ...
Guanxin Huang, Minjie Liu, Fangjun Xiong, Ge Meng, Yuan Tao, Yan Wu, Haihui Peng, Fener Chen   +7 more
doaj   +1 more source

Synthesis of dihydrofurans using nano-CuFe2O4@Chitosan

Journal of Saudi Chemical Society, 2017
An efficient multi-component synthesis of dihydrofurans is described by a one-pot condensation reaction of 2,4′-dibromoacetophenone, aromatic aldehydes and dimedone using nano-CuFe2O4@Chitosan under reflux conditions in ethanol.
Javad Safaei-Ghomi, Hossein Shahbazi-Alavi   +1 more
doaj   +1 more source

Cyclic Nitriles:  Diastereoselective Alkylations

, 2016
Diastereoselective alkylations of metalated conformationally locked 4-tert-butylcyclohexanecarbonitrile are highly diastereoselective with magnesium and copper counterions but only modestly diastereoselective with lithium as the counterion.
Fraser F. Fleming (1520524), Wang Liu (1683181), Subrahmanyam Gudipati (2471455), Omar W. Steward (2287948), Zhiyu Zhang (571356)   +4 more
core   +2 more sources

Three-component coupling of aryl iodides, allenes, and aldehydes catalyzed by a Co/Cr-hybrid catalyst

Beilstein Journal of Organic Chemistry, 2018
The cobalt/chromium-catalyzed three-component coupling of aryl iodides, allenes, and aldehydes has been developed to afford multi-substituted homoallylic alcohols in a diastereoselective manner.
Kimihiro Komeyama, Shunsuke Sakiyama, Kento Iwashita, Itaru Osaka, Ken Takaki   +4 more
doaj   +1 more source

Modular and Stereoselective Synthesis of Cyclobutane β‐Amino Alcohols

Angewandte Chemie, EarlyView.
Late‐stage functionalization and photoisomerization of 1,2‐azaborine leads to a general strategy for the synthesis of diversely substituted cyclobutane β‐amino alcohols. The relative stereochemistry of the resulting products is unambiguously defined by the stereospecific and stereoselective nature of the photoisomerization‐hydrogenation‐oxidation ...
Xinyu Yang, Tomoya Ozaki, Bo Li, Shih‐Yuan Liu   +3 more
wiley   +2 more sources

Nickel-Catalyzed Kumada Cross-Coupling Reactions of Benzylic Sulfonamides

Molecules, 2021
Herein, we report a Kumada cross-coupling reaction of benzylic sulfonamides. The scope of the transformation includes acyclic and cyclic sulfonamide precursors that cleanly produce highly substituted acyclic fragments.
Kirsten A. Hewitt, Claire A. Herbert, Alissa C. Matus, Elizabeth R. Jarvo   +3 more
doaj   +1 more source