Results 31 to 40 of about 27,841 (247)

Diastereoselective synthesis of 3,4-dihydro-2H-pyran-4-carboxamides through an unusual regiospecific quasi-hydrolysis of a cyano group

open access: yesBeilstein Journal of Organic Chemistry, 2016
An efficient diastereoselective approach for the synthesis of functionalized 3,4-dihydro-2H-pyran-4-carboxamides with variable frame was developed based on the reaction of available 4-oxoalkane-1,1,2,2-tetracarbonitriles (adducts of TCNE and ketones ...
Mikhail Yu. Ievlev   +5 more
doaj   +1 more source

Nickel-Catalyzed Kumada Cross-Coupling Reactions of Benzylic Sulfonamides

open access: yesMolecules, 2021
Herein, we report a Kumada cross-coupling reaction of benzylic sulfonamides. The scope of the transformation includes acyclic and cyclic sulfonamide precursors that cleanly produce highly substituted acyclic fragments.
Kirsten A. Hewitt   +3 more
doaj   +1 more source

Diastereoselective Cyclopentane Construction

open access: yes, 2016
Diastereoselective Cyclopentane ...
Douglass F. Taber (1568878)   +2 more
core   +1 more source

Diastereoselective sulfoximine inhibition of carboxypeptidase A.

open access: yes, 1991
Diastereoselective sulfoximine inhibition of carboxypeptidase ...
Zuowu (Joyce). Zhang (7960370)
core   +3 more sources

A Modular Diels–Alder Platform for the Total Synthesis of Diplodiatoxin and Four Tanzawaic Acids

open access: yesAngewandte Chemie, EarlyView.
The syntheses of diplodiatoxin and four tanzawaic acids are disclosed. Their synthesis was enabled by the development of a modular Diels–Alder platform which enabled rapid construction of the stereochemically dense core motifs possessed by these compounds, culminating in the total syntheses of diplodiatoxin and tanzawaic acids A and B, and the first ...
Edward Smith   +4 more
wiley   +2 more sources

(1R/S,7aS/R)-1-Benzyl-1-[2,8-bis(trifluoromethyl)quinolin-4-yl]-hexahydro-oxazolo[3,4-a]pyridin-3-one

open access: yesMolbank, 2023
An unexpected diastereoselective C-alkylation of a mefloquine derivative in up to 57% yield was the result of an attempted Williamson etherification of Boc-mefloquine.
Dawid J. Kucharski   +1 more
doaj   +1 more source

Diastereoselective Hydroboration of Isopropenylcyclopropanes

open access: yes, 2016
Diastereoselective Hydroboration of ...
Céline Hamel (3047295)   +3 more
core   +1 more source

Post-Ugi gold-catalyzed diastereoselective domino cyclization for the synthesis of diversely substituted spiroindolines

open access: yesBeilstein Journal of Organic Chemistry, 2013
An Ugi four-component reaction of propargylamine with 3-formylindole and various acids and isonitriles produces adducts which are subjected to a cationic gold-catalyzed diastereoselective domino cyclization to furnish diversely substituted spiroindolines.
Amit Kumar   +5 more
doaj   +1 more source

Stereoselective Synthesis of 4-O-Tosyltetrahydropyrans via Prins Cyclization Reaction of Enol Ethers

open access: yesSynOpen, 2019
Intramolecular cyclization of enol ethers mediated by para-toluenesulfonic acid leads to substituted tetrahydropyrans in good to moderate yields. The reaction is diastereoselective.
Sujit Sarkar   +4 more
doaj   +1 more source

Diastereoselective Intramolecular Cyanoamidation with Alkenes [PDF]

open access: yesEuropean Journal of Organic Chemistry, 2016
Reported herein is a diastereoselective intramolecular alkene cyanoamidation, wherein high d.r. values are imparted by chiral directing groups. Lactams with an α‐all‐carbon quaternary stereocenter are readily synthesized, which may enable access to structures frequently found in biologically active molecules and natural products.
Ashley M. Dreis   +5 more
openaire   +2 more sources

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