Results 11 to 20 of about 23,776 (268)

Redox‐Neutral and Diastereoselective Cross‐Pinacol Coupling of Pyridyl Ketones With Amine‐Derived Aldehydes

ChemistryEurope
Controlling the cross‐selectivity and diastereoselectivity in cross‐pinacol coupling reactions remains challenging. Herein, we report a redox‐neutral strategy that enables the cross‐selective pinacol coupling between pyridyl ketones and amine‐derived ...
Takahito Kuribara, Katsuma Ando, Ayahito Kaneki, Tetsuhiro Nemoto   +3 more
doaj   +2 more sources

Diastereoselective arylation of l-proline derivatives at the 5-position [PDF]

, 2008
Diastereoselective introduction of nucleophiles into L-proline derivatives at the 5-position was achieved with suitable selection of N-protecting group.
Demizu, Yosuke, Matsumura, Yoshihiro, Onomura, Osamu, Tsukada, Shinsuke, Kirira, Peter G, Tanaka, Toshimitsu   +5 more
core   +1 more source

Ag(I)/PPh3-Catalyzed Diastereoselective Syntheses of the Spiro[indole-3,4\u27-piperidine] Scaffold and Its Derivatives via Chelation-Controlled Cycloisomerizations of Tryptamine-Ynamides

, 2021
A Ag(I)/PPh3-catalyzed chelation-controlled cycloisomerization of tryptamine-ynamide was developed to access the spiro[indole-3,4\u27-piperidine] scaffold.
Maosheng, Cheng, Shitao, Sun, Fukai, Xie, Zhaobo, Wang, Di, Zhang, Yanyu, Chen, Junpeng, Zhang, Lu, Yang, Bin, Lin, Yongxiang, Liu   +9 more
core   +1 more source

Diastereoselective Synthesis of 5-Hydroxy-8-methoxy-1-oxaspiro[5,5]undeca-7,10-diene-9-one

Molecules, 2013
A short five steps synthesis of the title compound from vanillin is described. The racemic spiroether 7 was obtained in 61% yield and in >99% diastereomeric excess (by 1H-NMR) from the corresponding phenolic derivative 3 by oxidation with lead (IV)
Thomas W. Scully, Guy L. Plourde
doaj   +1 more source

Intermolecular diastereoselective annulation of azaarenes into fused N-heterocycles by Ru(II) reductive catalysis

Nature Communications, 2022
Derivatization of azaarenes can create molecules of biological importance, but reductive functionalization of weakly reactive azaarenes remains a challenge. Here the authors show a dearomative, diastereoselective annulation of azaarenes, via ruthenium(II)
He Zhao, Yang Wu, Chenggang Ci, Zhenda Tan, Jian Yang, Huanfeng Jiang, Pierre H. Dixneuf, Min Zhang   +7 more
doaj   +1 more source

Enantio- and Diastereoselective Synthesis of Homoallylic α-Trifluoromethyl Amines by Catalytic Hydroalkylation of Dienes

, 2020
We describe a strategy for the enantio- and diastereoselective synthesis of homoallylic α-trifluoromethyl amines by the catalytic hydroalkylation of terminal dienes.
Steven, Malcolmson, Chibueze I., Onyeagusi, Xinxin, Shao   +2 more
core   +1 more source

Diastereoselective synthesis of new O-alkylated and C-branched inositols and their corresponding fluoro analogues

Beilstein Journal of Organic Chemistry, 2016
Efficient routes were developed for the diastereoselective synthesis of new O-alkylated and C-branched inositols and their corresponding fluoro analogues.
Charlotte Collet, Françoise Chrétien, Yves Chapleur, Sandrine Lamandé-Langle   +3 more
doaj   +1 more source

Reenvisioning the De Mayo Reaction: A Boron‐Enabled Cycloaddition Approach

Angewandte Chemie, EarlyView.
An oxa‐boracycle conformational lock strategy enables photocatalytic [2+2] cycloaddition to afford densely substituted cyclobutylboronates. The conformational constraint suppresses triplet relaxation and promotes productive bimolecular reactivity.
Neetu Sharma, Yanyao Liu, Partha Sarathi Hazra, Evan B. Piper, Ryan Van Hoveln, Michael Kevin Brown   +5 more
wiley   +2 more sources

Cyclic Nitriles:  Diastereoselective Alkylations

, 2016
Diastereoselective alkylations of metalated conformationally locked 4-tert-butylcyclohexanecarbonitrile are highly diastereoselective with magnesium and copper counterions but only modestly diastereoselective with lithium as the counterion.
Fraser F. Fleming (1520524), Wang Liu (1683181), Subrahmanyam Gudipati (2471455), Omar W. Steward (2287948), Zhiyu Zhang (571356)   +4 more
core   +2 more sources

Catalytic Enantioselective Multicomponent Reactions of Sulfoxonium Ylides Enabled by a Formal Rearrangement—A Versatile Entry to Enantioenriched α‐Sulfanyl Carbonyl Compounds

Angewandte Chemie, EarlyView.
A catalytic network embedding a formal rearrangement enables the first catalytic enantioselective multicomponent reaction (MCR) of sulfur ylides. In the presence of a bulky chiral phosphoric acid, the reaction combines sulfoxonium ylides, aldehydes and thiols, and affords synthetically versatile β‐hydroxy‐α‐sulfanyl carbonyl compounds in ...
Nicolò Santarelli, Pietro Pecchini, Nunzio Matera, Andrea Pellegrini, Riccardo Fabbri, Irati Celada Cubero, Leire Navarro Rubio, Cristina Di Pietro, Andrea Mazzanti, Mariafrancesca Fochi, Luca Bernardi   +10 more
wiley   +2 more sources