Results 121 to 130 of about 1,190,888 (379)

Dietary fat intake as a risk factor for the development of diabetes. Multinational, multicenter study of the Mediterranean Group for the Study of Diabetes (MGDS) [PDF]

, 2003
In the context of the Multinational MGSD Nutrition Study, three groups of subjects were studied: 204 subjects with recently diagnosed diabetes(RDM),42subjectswithundiagnoseddiabetes(UDM)(AmericanDiabetesAssociation criteria—fasting plasma glucose [FPG ...
ANGELICO, Francesco, ASSAADKHALIL S., BARBATO A., DEL BEN, Maria, DIMITRIJEVICSRECKOVIC V., DJORDJEVIC P., GALLOTTI C., KARAMANOS B., KATSILAMBROS N., MIGDALIS I., MRABET M, PETKOVA M., ROUSSI D., TENCONI M. T., THANOPOULOU A.   +14 more
core   +1 more source

MCT1‐mediated Lactate Shuttle to Mitochondria Governs Macrophage Polarization and Modulates Glucose Homeostasis by Affecting β Cells

Advanced Science, EarlyView.
This study demonstrates that the transport of lactate to the mitochondria is of critical importance in determining the functions of macrophages by altering mitochondrial respiration. In macrophages, this lactate transport mechanism regulates glucose homeostasis by influencing the functions of insulin‐secreting cells in the pancreatic islets.
Lingling Chen, Yijun Lin, Xinyu Zhu, Shixuan Zhuo, Zixuan Li, Cheng Guo, Xiaoyi Ye, Jinzhu Chen, Shuying Wang, Yan Chen   +9 more
wiley   +1 more source

The Role of Supplemental Complex Dietary Carbohydrates and Gut Microbiota in Promoting Cardiometabolic and Immunological Health in Obesity: Lessons from Healthy Non-Obese Individuals

Frontiers in Nutrition, 2017
Dietary supplementation with complex carbohydrates is known to alter the composition of gut microbiota, and optimal implementation of the use of these so called “prebiotics” could be of great potential in prevention and possibly treatment of obesity and ...
Petra C. Vinke, Sahar El Aidy, Gertjan van Dijk   +2 more
doaj   +1 more source

Dietary fat and total energy intake modifies the association of genetic profile risk score on obesity: evidence from 48 170 UK Biobank participants [PDF]

, 2017
Background: Obesity is a multifactorial condition influenced by both genetics and lifestyle. The aim of this study was to investigate whether the association between a validated genetic profile risk score for obesity (GPRS-obesity) and body mass index ...
Anderson, Jana, Bailey, Mark E.S., Celis-Morales, Carlos, Gill, Jason M.R., Gray, Stuart, Guo, Yibing, Iliodromiti, Stamatina, Lyall, Donald M., Mackay, Daniel F., Pell, Jill, Petermann, Fanny, Sattar, Naveed, Steell, Lewis, Welsh, Paul   +13 more
core   +1 more source

The Non‐Canonical ChREBPα Activity Suppresses the Activation of Hepatic Stellate Cells and Liver Fibrosis by Antagonizing TGF‐β‐E2F1 Axis

Advanced Science, EarlyView.
Intrahepatic microenvironment greatly impacts duration and degree of HSCs activation and development of liver fibrosis. By inhibiting TGFβ‐E2F1‐driven production of profibrogenic factors (CTGF and THBS1), hepatocyte ChREBPα monitors hepatic microenvironment and suppresses the overactivation of HSCs.
Jian Zhang, Yuee Zhao, Gauthami Pulivendala, Qing Zhang, Liangyou Rui, Jiashi Gao, Huiwen Wang, Gary Zhang, Alli Nuotio‐Antar, Xin Tong, Lei Yin   +10 more
wiley   +1 more source

Hepatic Steatosis, Carbohydrate Intake, and Food Quotient in Patients with NAFLD

International Journal of Endocrinology, 2013
Is steatosis related to the spontaneous carbohydrate intake in patients with NAFLD? We performed dietary records for 24 patients with NAFLD, 3 months after their liver biopsy was performed and before the deliverance of a dietary advice. The food quotient,
Concepcion Gonzalez, Victor de Ledinghen, Julien Vergniol, Juliette Foucher, Brigitte Le Bail, Sabrina Carlier, Elisa Maury, Henri Gin, Vincent Rigalleau   +8 more
doaj   +1 more source

The role and requirements of digestible dietary carbohydrates in infants and toddlers

European Journal of Clinical Nutrition, 2012
Digestible carbohydrates are one of the main sources of dietary energy in infancy and childhood and are essential for growth and development. The aim of this narrative review is to outline the intakes of digestible carbohydrates and their role in health ...
A. Stephen, M. Alles, C. Graaf, M. Fleith, E. Hadjilucas, E. Isaacs, C. Maffeis, G. Zeinstra, C. Matthys, Á. Gil   +9 more
semanticscholar   +1 more source

Alistipes senegalensis is Critically Involved in Gut Barrier Repair Mediated by Panax Ginseng Neutral Polysaccharides in Aged Mice

Advanced Science, EarlyView.
An integral functional axis through which GPN and functional metabolites of Alistipes senegalensis can hydrolyze tryptophan into indoles. Furthermore, the Alistipes senegalensis‐indole‐AhR pathway is found to be associated with increased expression of tight junction‐associated proteins and activation of gut stem cells.
Dandan Wang, Hui Wang, Yingna Li, Jing Lu, Xiaolei Tang, Dan Yang, Manying Wang, Daqing Zhao, Fangbing Liu, Shuai Zhang, Liwei Sun   +10 more
wiley   +1 more source

Prebiotic Properties of Carbohydrates in the Formation of Children’s Health

Zdorovʹe Rebenka, 2013
Сontent of dietary fibers, pectin and fibers in modern products is studied. The necessity for dysbiosis prevention is established on the basis of prebiotic properties of carbohydrates providing a synthesis of metabolites of two types (macroorganism and ...
N.G. Mikryukova
doaj   +1 more source

Carbohydrates, dietary fiber, and incident type 2 diabetes in older women.

American Journal of Clinical Nutrition, 2000
BACKGROUND Dietary carbohydrates may influence the development of type 2 (non-insulin-dependent) diabetes, for example, through effects on blood glucose and insulin concentrations. OBJECTIVE We examined the relations of baseline intake of carbohydrates,
K. Meyer, L. Kushi, D. Jacobs, J. Slavin, T. Sellers, A. Folsom   +5 more
semanticscholar   +1 more source