Results 81 to 90 of about 2,043,354 (309)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Effect of Metabolites on Growth, and Differentiation in the Colon-Group.

open access: yesExperimental Biology and Medicine, 1937
The subdivision of the colon-group of bacteria into distinct subgroups is still a problem despite many studies. The genera Escher-ichia and Aerobacter can be differentiated from each other by nearly a dozen correlated characters. The genus Aerobacter can be further subdivided on correlated characters into at least 2 distinct subgroups represented by ...
M. J. Powers, M. Levine
openaire   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Differential metabolites

open access: yes
Differential metabolites and proteins(IFNT vs ...
xiao, jinbang
core   +1 more source

Distribution of differential metabolites in positive ion mode (ESI+) and negative ion mode (ESI-).

open access: yes, 2021
Distribution of differential metabolites in positive ion mode (ESI+) and negative ion mode (ESI-).
Chen Liu (75209)   +7 more
core   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Pathway enrichment analysis of differential metabolites of pSS and healthy controls.

open access: yes, 2022
Pathway enrichment analysis of differential metabolites of pSS and healthy controls.
Xiaoyan Liu (158152)   +6 more
core   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Integrated transcriptomic and metabolomic analysis to elucidate key genes and signaling pathways involved in the promotion of periodontitis by hypertension

open access: yesScientific Reports
To identify key genes and metabolites that promote the progression of periodontitis in the context of hypertension through combined transcriptomic and metabolomic analyses.
Haiqing Liao   +8 more
doaj   +1 more source

Identified differential metabolites in outcome HU+NAFLD vs. initial HU.

open access: yes, 2016
Identified differential metabolites in outcome HU+NAFLD vs. initial HU.
Xiaojuan He (1930795)   +13 more
core   +1 more source

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