Rough sets for in silico identification of differentially expressed miRNAs
International Journal of Nanomedicine, 2013 Sushmita Paul, Pradipta Maji Machine Intelligence Unit, Indian Statistical Institute, Kolkata, India Abstract: The microRNAs, also known as miRNAs, are the class of small noncoding RNAs. They repress the expression of a gene posttranscriptionally.
Paul S, Maji P
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dbDEMC: a database of differentially expressed miRNAs in human cancers [PDF]
BMC Genomics, 2010 Background MicroRNAs (miRNAs) are small noncoding RNAs about 22 nt long that negatively regulate gene expression at the post-transcriptional level.
Zhang Yangde +12 more
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Differentially Expressed miRNAs in Age-Related Neurodegenerative Diseases: A Meta-Analysis. [PDF]
Genes (Basel), 2022 To date, no neurodegenerative diseases (NDDs) have cures, and the underlying mechanism of their pathogenesis is undetermined. As miRNAs extensively regulate all biological processes and are crucial regulators of healthy brain function, miRNAs differentially expressed in NDDs may provide insight into the factors that contribute to the emergence of ...
Noronha O +5 more
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dbDEMC 3.0: Functional Exploration of Differentially Expressed miRNAs in Cancers of Human and Model Organisms. [PDF]
Genomics Proteomics Bioinformatics, 2022 Xu F +10 more
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UVB irradiation differential regulate miRNAs expression in skin photoaging
Anais Brasileiros de Dermatologia, 2022 UVB irradiation can cause acute damage such as sunburn, or photoaging and melanoma, all of which are major health threats.This study was designed to investigate the mechanism of skin photoaging induced by UVB radiation in mice through the analysis of the differential expression of miRNAs.A UVB irradiation photoaging model was constructed. HE and Masson
Yuan Fang +11 more
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BMC Medical Genomics, 2022 Background We aimed to explore mechanisms of development and progression of polycystic ovary syndrome (PCOS). Methods The microRNA expression microarray GSE37914 and gene expression profiles GSE43264 and GSE98421 were downloaded from the Gene Expression ...
Ziqian Sun +3 more
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Differential expression of mRNA-miRNAs related to intramuscular fat content in the longissimus dorsi in Xinjiang brown cattle. [PDF]
PLoS ONE, 2018 In this study, we examined the role of mRNAs and miRNAs in variations in intramuscular fat content in the longissimus dorsi muscle in Xinjiang brown cattle.
Na Li +8 more
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Identification of aberrantly methylated differentially expressed genes targeted by differentially expressed miRNA in osteosarcoma [PDF]
Annals of Translational Medicine, 2020 Osteosarcoma (OS) is the most common primary bone tumors diagnosed in children and adolescents. Recent studies have shown a prognostic role of DNA methylation in various cancers, including OS. The aim of this study was to identify the aberrantly methylated genes that are prognostically relevant in OS.The differentially expressed mRNAs, miRNAs and ...
Wang, Ting-Xuan +6 more
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BMC Plant Biology, 2021 Background Brassica napus is the third leading source of edible oil in the world. Genic male sterility (GMS) lines provide crucial material for harnessing heterosis for rapeseed.
Jianxia Jiang +9 more
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Meta-Analysis of Differential miRNA Expression after Bariatric Surgery [PDF]
Journal of Clinical Medicine, 2019 Bariatric surgery is an efficient treatment for weight loss in obese patients and for resolving obesity comorbidities. However, the mechanisms behind these outcomes are unclear. Recent studies have indicated significant alterations in the transcriptome after surgery, specifically in the differential expression of microRNAs.
Gladys Langi +2 more
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