Results 31 to 40 of about 126,237 (291)

Chromatin accessibility is associated with the changed expression of miRNAs that target members of the Hippo pathway during myoblast differentiation

Cell Death and Disease, 2020
miRNAs reportedly participate in various biological processes, such as skeletal muscle proliferation and differentiation. However, the regulation of differentially expressed (DE) miRNAs and their function in myogenesis remain unclear.
Huanhuan Zhou, Yue Xiang, Mingyang Hu, Yueyuan Xu, Ye Hou, Xiaolong Qi, Liangliang Fu, Yu Luan, Zhangxu Wang, Xinyun Li, Yunxia Zhao, Shuhong Zhao   +11 more
doaj   +1 more source

Differential Expression of Hyperhydricity Responsive Peach MicroRNAs

Journal of Integrative Bioinformatics, 2016
SummaryHyperhydricity is a syndrome that causes morpho-physiological malformations in tissue culture plantlets. Micro-RNAs (miRNA) are small non-coding RNAs that play important regulatory roles in plant development, stress response, and adaptation to environmental conditions. In this study, differential expression analysis indicated that miRNAs play an
Unver, Turgay, Diler, Ebru, KARAKÜLAH, GÖKHAN   +2 more
openaire   +4 more sources

Prognostic significance of differentially expressed miRNAs in esophageal cancer [PDF]

International Journal of Cancer, 2010
AbstractAltered microRNA (miRNA) expression has been found to promote carcinogenesis, but little is known about the role of miRNAs in esophageal cancer. In this study, we selected 10 miRNAs and analyzed their expression in 10 esophageal cancer cell lines and 158 tissue specimens using Northern blotting and in situ hybridization, respectively.
Yuxin, Hu, Arlene M, Correa, Ashraful, Hoque, Baoxiang, Guan, Fei, Ye, Jie, Huang, Stephen G, Swisher, Tsung Teh, Wu, Jaffer A, Ajani, Xiao-Chun, Xu   +9 more
openaire   +2 more sources

Bioinformatic screening for candidate biomarkers and their prognostic values in endometrial cancer

BMC Genetics, 2020
Background Endometrial cancer is a common gynecological cancer with annually increasing incidence worldwide. However, the biomarkers that provide prognosis and progression for this disease remain elusive.
Yaowei Li, Li Li
doaj   +1 more source

Differential expression of miRNAs in esophageal cancer tissue

Oncology Letters, 2013
The aim of this study was to explore the association of specific microRNAs (miRNAs) with the development of esophageal cancer (EC) and to identify new molecular markers for EC by analyzing the expression profiles of miRNAs in EC tissues. The expression profiles of miRNAs in paired EC and paracancerous normal tissues were detected and bioinformatically ...
LIU, SHANG-GUO, QIN, XIU-GUANG, ZHAO, BAO-SHENG, QI, BO, YAO, WEN-JIAN, WANG, TIAN-YUN, LI, HAN-CHEN, WU, XIANG-NAN   +7 more
openaire   +3 more sources

The miRNAome of the postpartum dairy cow liver in negative energy balance [PDF]

, 2014
peer-reviewedBackground: Negative energy balance (NEB) is an altered metabolic state in high yielding cows that occurs during the first few weeks postpartum when energy demands for lactation and maintenance exceed the energy supply from dietary ...
Fatima, Attia, Lynn, David J, Morris, Dermot G., O'Boyle, Padraic, Seoighe, Cathal   +4 more
core   +2 more sources

Differential Expression of miRNA-223 in Coronary In-Stent Restenosis [PDF]

Journal of Clinical Medicine, 2022
Objective: In-stent restenosis (ISR) is an unfavorable complication that occurs in patients after coronary stenting. Despite the progress with advent of modern DES and new antiplatelet agents, restenosis still hampers PCI short- and long-term results. The aim of this study was to investigate whether circulating miRNA-223, which is associated with HDL ...
Shiva Ganjali, Seyed Hamid Aghaee-Bakhtiari, Željko Reiner, Amirhossein Sahebkar   +3 more
openaire   +2 more sources

Identification of MicroRNA-Target Gene-Transcription Factor Regulatory Networks in Colorectal Adenoma Using Microarray Expression Data

Frontiers in Genetics, 2020
ObjectiveThe aim of the study was to find the key genes, microRNAs (miRNAs) and transcription factors (TFs) and construct miRNA-target gene-TF regulatory networks to investigate the underlying molecular mechanism in colorectal adenoma (CRA).MethodsFour ...
Yadong Gao, Yadong Gao, Shenglai Zhang, Shenglai Zhang, Yan Zhang, Yan Zhang, Junbo Qian, Junbo Qian   +7 more
doaj   +1 more source

Profound effect of profiling platform and normalization strategy on detection of differentially expressed microRNAs [PDF]

, 2012
Adequate normalization minimizes the effects of systematic technical variations and is a prerequisite for getting meaningful biological changes. However, there is inconsistency about miRNA normalization performances and recommendations.
Kaiser, Sebastian, Meyer, Swanhild U., Pfaffl, Michael W., Thirion, Christian, Wagner, Carola   +4 more
core   +1 more source

Differential expression of miRNAs in enterovirus 71-infected cells [PDF]

Virology Journal, 2015
Enterovirus 71 (EV71) is one of the major etiological pathogens of hand, foot and mouth disease (HFMD) and can cause severe cerebral and pulmonary complications and even fatality. MicroRNAs (miRNAs), a class of small non-coding RNA molecules, play an important role in post-transcriptional regulation of gene expression and thereby influencing various ...
Xun, Meng, Ma, Chao-Feng, Du, Quan-Li, Ji, Yan-Hong, Xu, Ji-Ru   +4 more
openaire   +2 more sources