Results 21 to 30 of about 85,965 (258)

Differential expression profiles of miRNA in the serum of sarcopenic rats

Biochemistry and Biophysics Reports, 2022
As the geriatric population and life expectancy increase, the interest in preventing geriatric diseases, such as sarcopenia, is increasing. However, the causes of sarcopenia are unclear, and current diagnostic methods for sarcopenia are unreliable.
Wonjong Yu, Min-kyu Yang, Dong Jun Sung, Tae Jun Park, Myungchul Kim, Eustache Ntigura, Sung Hea Kim, Bokyung Kim, Sang Woong Park, Young Min Bae   +9 more
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Differential Expression of miRNAs in Amyotrophic Lateral Sclerosis Patients

Molecular Neurobiology, 2023
AbstractAmyotrophic lateral sclerosis (ALS) is a progressive motor neuron disease that affects nerve cells in the brain and spinal cord, causing loss of muscle control, muscle atrophy and in later stages, death. Diagnosis has an average delay of 1 year after symptoms onset, which impairs early management.
Bruno Costa Gomes, Nuno Peixinho, Rita Pisco, Marta Gromicho, Ana Catarina Pronto-Laborinho, José Rueff, Mamede de Carvalho, António Sebastião Rodrigues   +7 more
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Differential expression of miRNAs in esophageal cancer tissue

Oncology Letters, 2013
The aim of this study was to explore the association of specific microRNAs (miRNAs) with the development of esophageal cancer (EC) and to identify new molecular markers for EC by analyzing the expression profiles of miRNAs in EC tissues. The expression profiles of miRNAs in paired EC and paracancerous normal tissues were detected and bioinformatically ...
LIU, SHANG-GUO, QIN, XIU-GUANG, ZHAO, BAO-SHENG, QI, BO, YAO, WEN-JIAN, WANG, TIAN-YUN, LI, HAN-CHEN, WU, XIANG-NAN   +7 more
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Chromatin accessibility is associated with the changed expression of miRNAs that target members of the Hippo pathway during myoblast differentiation

Cell Death and Disease, 2020
miRNAs reportedly participate in various biological processes, such as skeletal muscle proliferation and differentiation. However, the regulation of differentially expressed (DE) miRNAs and their function in myogenesis remain unclear.
Huanhuan Zhou, Yue Xiang, Mingyang Hu, Yueyuan Xu, Ye Hou, Xiaolong Qi, Liangliang Fu, Yu Luan, Zhangxu Wang, Xinyun Li, Yunxia Zhao, Shuhong Zhao   +11 more
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Bioinformatic screening for candidate biomarkers and their prognostic values in endometrial cancer

BMC Genetics, 2020
Background Endometrial cancer is a common gynecological cancer with annually increasing incidence worldwide. However, the biomarkers that provide prognosis and progression for this disease remain elusive.
Yaowei Li, Li Li
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Identification of MicroRNA-Target Gene-Transcription Factor Regulatory Networks in Colorectal Adenoma Using Microarray Expression Data

Frontiers in Genetics, 2020
ObjectiveThe aim of the study was to find the key genes, microRNAs (miRNAs) and transcription factors (TFs) and construct miRNA-target gene-TF regulatory networks to investigate the underlying molecular mechanism in colorectal adenoma (CRA).MethodsFour ...
Yadong Gao, Yadong Gao, Shenglai Zhang, Shenglai Zhang, Yan Zhang, Yan Zhang, Junbo Qian, Junbo Qian   +7 more
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Discovery of porcine microRNAs and profiling from skeletal muscle tissues during development. [PDF]

PLoS ONE, 2008
MiRNAs (microRNAs) play critical roles in many important biological processes such as growth and development in mammals. In this study, we identified hundreds of porcine miRNA candidates through in silico prediction and analyzed their expression in ...
Ting-Hua Huang, Meng-Jin Zhu, Xin-Yun Li, Shu-Hong Zhao   +3 more
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Prognostic significance of differentially expressed miRNAs in esophageal cancer [PDF]

International Journal of Cancer, 2010
AbstractAltered microRNA (miRNA) expression has been found to promote carcinogenesis, but little is known about the role of miRNAs in esophageal cancer. In this study, we selected 10 miRNAs and analyzed their expression in 10 esophageal cancer cell lines and 158 tissue specimens using Northern blotting and in situ hybridization, respectively.
Yuxin, Hu, Arlene M, Correa, Ashraful, Hoque, Baoxiang, Guan, Fei, Ye, Jie, Huang, Stephen G, Swisher, Tsung Teh, Wu, Jaffer A, Ajani, Xiao-Chun, Xu   +9 more
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Differential Expression of Tissular miRNA-155 in Pediatric Gastritis

Journal of Clinical Medicine, 2022
Background: MicroRNA molecules, among them the intensely studied miRNA-155 (miR-155), are regarded as potential biomarkers of chronic gastric inflammation and premalignant lesion progression. However, literature data are scarce in terms of pediatric studies and in the evaluation of the predictive role of miRNA in early gastric inflammation.
Săsăran Maria Oana, Bănescu Claudia, Riza Anca Lelia, Mocan Simona, Cârstea Claudia, Dobru Ecaterina Daniela   +5 more
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Differential expression of miRNA 155 and miRNA 146a in Parkinson's disease patients

eNeurologicalSci, 2018
Parkinson's disease is a neurodegenerative disorder and its etiology is unknown, numerous studies show how different environmental factors can influence the development of disease. miRNAs are involved in several pathologies and their dysregulation contribute to different pathologies, also in neurodegenerative such as Parkinson's disease, Alzheimer's ...
Elisa Caggiu, Kai Paulus, Giuseppe Mameli, Giannina Arru, Gian Pietro Sechi, Leonardo A. Sechi   +5 more
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