Results 41 to 50 of about 4,395,934 (279)

A Mouse Model for Imprinting of the Human Retinoblastoma Gene. [PDF]

PLoS ONE, 2015
The human RB1 gene is imprinted due to integration of the PPP1R26P1 pseudogene into intron 2. PPP1R26P1 harbors the gametic differentially methylated region of the RB1 gene, CpG85, which is methylated in the female germ line.
Vasiliki Tasiou, Michaela Hiber, Laura Steenpass   +2 more
doaj   +1 more source

Identification of differentially methylated regions in rare diseases from a single-patient perspective

Clinical Epigenetics, 2022
Background DNA methylation (5-mC) is being widely recognized as an alternative in the detection of sequence variants in the diagnosis of some rare neurodevelopmental and imprinting disorders.
Robin Grolaux, Alexis Hardy, Catharina Olsen, S. Van Dooren, G. Smits, Matthieu Defrance   +5 more
semanticscholar   +1 more source

An evaluation of the genome-wide false positive rates of common methods for identifying differentially methylated regions using illumina methylation arrays

Epigenetics, 2022
Differentially methylated regions (DMRs) are genomic regions with specific methylation patterns across multiple loci that are associated with a phenotype.
Yuanchao Zheng, Kathryn L. Lunetta, Chunyu Liu, Seyma Katrinli, Alicia K. Smith, Mark W. Miller, Mark W. Logue   +6 more
doaj   +1 more source

Differentially methylated CpG sites

, 2022
4009 differentially methylated CpG sites  between 460 LUAD and 32 normal lung tissues 
Xiao (12199865)
core   +1 more source

Correlation plots as for under-expressed/hyper-methylated validated Differentially Expressed Genes-Differentially Methylated Genes (vDEGs-DMGs).

, 2022
Correlation plots as for under-expressed/hyper-methylated validated Differentially Expressed Genes-Differentially Methylated Genes (vDEGs-DMGs).
Amir Mehrgou (12295124), Shahram Teimourian (12295127)   +1 more
core   +1 more source

Characterization of N6-methyladenosine in cattle-yak testis tissue

Frontiers in Veterinary Science, 2022
N6-methyladenosine (m6A) is the most common form of eukaryotic mRNA modification, and it has been shown to exhibit broad regulatory activity in yeast, plants, and mammals.
Xingdong Wang, Xingdong Wang, Jie Pei, Jie Pei, Shaoke Guo, Shaoke Guo, Mengli Cao, Mengli Cao, Yandong Kang, Yandong Kang, Lin Xiong, Lin Xiong, Yongfu La, Yongfu La, Pengjia Bao, Pengjia Bao, Chunnian Liang, Chunnian Liang, Ping Yan, Ping Yan, Xian Guo, Xian Guo   +21 more
doaj   +1 more source

Identification of Imprinting Regulators at the Meg3 Differentially Methylated Region [PDF]

, 2013
Identification of Imprinting Regulators as the Meg3 Differentially Methylated Region Erin Nichole McMurray, PhD Department of Biological Sciences University of Illinois at Chicago Chicago, Illinois (2012) Dissertation Chairperson: Dr.
Erin N. McMurray (7935722)
core   +6 more sources

Parallel profiling of DNA methylation and hydroxymethylation highlights neuropathology-associated epigenetic variation in Alzheimer’s disease

Clinical Epigenetics, 2019
Background Alzheimer’s disease is a progressive neurodegenerative disorder that is hypothesized to involve epigenetic dysfunction. Previous studies of DNA modifications in Alzheimer’s disease have been unable to distinguish between DNA methylation and ...
Adam R. Smith, Rebecca G. Smith, Ehsan Pishva, Eilis Hannon, Janou A. Y. Roubroeks, Joe Burrage, Claire Troakes, Safa Al-Sarraj, Carolyn Sloan, Jonathan Mill, Daniel L. van den Hove, Katie Lunnon   +11 more
doaj   +1 more source

Correlation plots as for over-expressed/hypo-methylated validated Differentially Expressed Genes-Differentially Methylated Genes (vDEGs-DMGs).

, 2022
Correlation plots as for over-expressed/hypo-methylated validated Differentially Expressed Genes-Differentially Methylated Genes (vDEGs-DMGs).
Amir Mehrgou (12295124), Shahram Teimourian (12295127)   +1 more
core   +1 more source

Discovered Key CpG Sites by Analyzing DNA Methylation and Gene Expression in Breast Cancer Samples

Frontiers in Cell and Developmental Biology, 2022
Breast cancer is the most common cancer in the world, and DNA methylation plays a key role in the occurrence and development of breast cancer. However, the effect of DNA methylation in different gene functional regions on gene expression and the effect ...
Yan-Ni Cao, Qian-Zhong Li, Qian-Zhong Li, Yu-Xian Liu   +3 more
doaj   +1 more source