Results 51 to 60 of about 4,395,934 (279)
Alterations in DNA methylation profiles in cancellous bone of postmenopausal women with osteoporosis
FEBS Open Bio, 2020 Osteoporosis is characterized by systemic microarchitecture impairment and bone loss, which ultimately lead to fragility fractures. This disease is most common in older people, especially in postmenopausal women.
Yu Zhou +7 more
doaj +1 more source
An epigenomic meta-analysis of differentially methylated sites in pre- and Post-Metabolic/Bariatric Surgery Adult Female Patients [PDF]
Background/Objectives: Metabolic/bariatric surgery is currently the most successful treatment for patients with obesity; however, a fifth of patients undergoing surgery may not lose enough weight to be considered successful.
Lovett, A. +5 more
core +1 more source
, 2015 Methylation status for differentially methylated probes (DMPs) or functionally- changed differentially methylated probes (fDMPs).
Paul D. Ray (819239) +5 more
core +1 more source
Differentially methylated positions.
, 2019 Differentially methylated positions.
Jefferey L. Burgess (65119) +13 more
core +1 more source
Mbd1 is recruited to both methylated and nonmethylated CpGs via distinct DNA binding domains [PDF]
, 2004 MBD1 is a vertebrate methyl-CpG binding domain protein (MBD) that can bring about repression of methylated promoter DNA sequences. Like other MBD proteins, MBD1 localizes to nuclear foci that in mice are rich in methyl-CpG.
Bird, Adrian P; id_orcid +2 more
core +1 more source
Title: Hypermethylation of miRNA Genes During Nodule Development
Frontiers in Molecular Biosciences, 2021 DNA methylation has recently emerged as a powerful regulatory mechanism controlling the expression of key regulators of various developmental processes, including nodulation. However, the functional role of DNA methylation in regulating the expression of
Sarbottam Piya +6 more
doaj +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Differentially methylated regions.
, 2019 Differentially methylated regions.
Jefferey L. Burgess (65119) +13 more
core +1 more source
Frontiers in Endocrinology, 2022 Gestational diabetes mellitus (GDM) “program” an elevated risk of metabolic syndrome in the offspring. Epigenetic alterations are a suspected mechanism.
Wen-Juan Wang +19 more
doaj +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source