Results 81 to 90 of about 1,615,993 (252)

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Optimum Digestible Valine to Lysine Ratio for Meat-Type Quails from 15 to 35 Days of Age

Brazilian Journal of Poultry Science
This study was conducted to estimate the dig. valine to lysine (Val:Lys) ideal ratio for meat-type quails from 15 to 35 d of age. A total of 385, 15-day-old not sexed quails, were randomly assigned to five treatments, each one seven times replicated with
WJ Alves, GS Viana, SLT Barreto, JCL Muniz, MI Hannas, AD Silva, PR Arnaut, VRMS Barros   +7 more
doaj   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

Postprandial Levels of Branch Chained and Aromatic Amino Acids Associate with Fasting Glycaemia [PDF]

, 2016
High fasting plasma concentrations of isoleucine, phenylalanine, and tyrosine have been associated with increased risk of hyperglycaemia and incidence of type 2 diabetes. Whether these associations are diet or metabolism driven is unknown.
Nilsson, Jeanette, Ericson, Ulrika, Magnusson, Martin, Fernandez, Celine, Almgren, Peter, Ottosson, Filip, Melander, Olle, Ericson, Ulrika,, Almgren, Peter,, Fernandez, Celine,, Magnusson, Martin,, Melander, Olle,, Lund University., Ottosson, Filip,   +13 more
core   +2 more sources

Sunflower meal for broilers of 22 to 42 days of age

Revista Brasileira de Zootecnia, 2011
The objective of the present experiment was to evaluate the inclusion of sunflower meal in diets formulated on total or digestible amino acid basis fed to broilers of 22 to 42 days of age.
Lúcio Francelino Araújo, Cristiane Soares da Silva Araújo, Natália Barros Petroli, Antonio Carlos de Laurentiz, Ricardo de Albuquerque, Messias Alves de Trindade Neto   +5 more
doaj   +1 more source

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Different criteria for feed formulation based on digestible amino acids for broilers

Brazilian Journal of Poultry Science, 2006
An experiment was carried out to evaluate different criteria in feed formulation based on digestible amino acids for broilers during the grower phase. Diets were formulated according to the recommendations for digestible methionine, methionine + cysteine,
LF Araújo, OM Junqueira, CSS Araújo, AC Laurentiz, V Assuena, GA Gomes   +5 more
doaj   +1 more source

Age-related changes of muscle and plasma amino acids in healthy children

, 2010
The aim of the study was to explore if changes in muscle and plasma amino acid concentrations developed during growth and differed from levels seen in adults.
Andersson, Kerstin,, Wernerman, Jan,, Hammarqvist, Folke,, Angsten, Gertrud,, Meurling, Staffan,, Wernerman, J,, Angsten, G, Andersson, K, Hammarqvist, F,, Meurling, S   +9 more
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Performance and nitrogen balance of laying hens fed increasing levels of digestible lysine and arginine

Revista Brasileira de Zootecnia, 2012
The objective of this experiment was to evaluate the effect of two digestible lysine levels and four digestible arginine levels on laying hens from 24 to 48 weeks of age.
Fabyola Barros de Carvalho, José Henrique Stringhini, Maíra Silva Matos, Roberto Moraes Jardim Filho, Marcos Barcellos Café, Nadja Susana Mogyca Leandro, Maria Auxiliadora Andrade   +6 more
doaj   +1 more source