Results 81 to 90 of about 1,286,089 (305)

A mutation in amino acid permease AAP6 reduces the amino acid content of the Arabidopsis sieve elements but leaves aphid herbivores unaffected [PDF]

, 2010
The aim of this study was to investigate the role of the amino acid permease gene AAP6 in regulating phloem amino acid composition and then to determine the effects of this altered diet on aphid performance.
Newbury, H. J., Hunt, E. (Emma), Gattolin, Stefano, Pritchard, J. (Jeremy), Tseng, Hua-Ming, Bale, J. S. (Jeffrey S.), Barrett, D. A. (David A.)   +6 more
core   +2 more sources

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Determination of true digestible amino acids of feedstuffs utilizing cecectomized roosters

Revista Brasileira de Zootecnia, 2012
The objective of this study was to estimate the true digestibility coefficients of amino acids and digestible amino acid values of some poultry feedstuffs.
Eliane Aparecida da Silva, Luiz Fernando Teixeira Albino, Horacio Santiago Rostagno, Rodolfo Alves Vieira, Valdir Ribeiro Junior, Anastácia Maria de Araújo Campos, João Paulo Leles Pereira   +6 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Digestible lysine levels in diets supplemented with ractopamine

Revista Brasileira de Zootecnia, 2011
In order evaluate digestible lysine levels in diets supplemented with 20 ppm of ractopamine on the performance and carcass traits, 64 barrows with high genetic potential at finishing phase were allotted in a completely randomized block design with four ...
Evelar de Oliveira Souza, Douglas Haese, João Luís Kill, Ismail Ramalho Haddade, Elcio das Graça Lacerda, Alysson Saraiva, Francisco Carlos de Oliveira Silva, Rodrigo Pereira Sobreiro   +7 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Optimum Digestible Valine to Lysine Ratio for Meat-Type Quails from 15 to 35 Days of Age

Brazilian Journal of Poultry Science
This study was conducted to estimate the dig. valine to lysine (Val:Lys) ideal ratio for meat-type quails from 15 to 35 d of age. A total of 385, 15-day-old not sexed quails, were randomly assigned to five treatments, each one seven times replicated with
WJ Alves, GS Viana, SLT Barreto, JCL Muniz, MI Hannas, AD Silva, PR Arnaut, VRMS Barros   +7 more
doaj   +1 more source

Digestible sulfur amino acid requirement of starting turkeys

Poultry Science, 1997
Three experiments (a total of 1,020 poults) were conducted to determine the digestible sulfur amino acid (SAA) requirement for female turkey poults during the starter period. Poults were fed a standard corn-soybean meal diet (PC) that met or exceeded NRC recommendations (28% CP, 3,172 kcal MEn/kg) for 1 wk and were then randomly assigned to treatments ...
S D, Boling, J D, Firman
openaire   +2 more sources

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Sunflower meal for broilers of 22 to 42 days of age

Revista Brasileira de Zootecnia, 2011
The objective of the present experiment was to evaluate the inclusion of sunflower meal in diets formulated on total or digestible amino acid basis fed to broilers of 22 to 42 days of age.
Lúcio Francelino Araújo, Cristiane Soares da Silva Araújo, Natália Barros Petroli, Antonio Carlos de Laurentiz, Ricardo de Albuquerque, Messias Alves de Trindade Neto   +5 more
doaj   +1 more source