Results 71 to 80 of about 10,900 (273)

The Renaissance of Digitoxin Is Overdue [PDF]

open access: yesDeutsches Ärzteblatt international, 2016
A 12-page review article on heart failure is very commendable (1). However, it is a source of irritation that in such a comprehensive article, a total of six lines is all that is given to the positive inotropic digitalis glycosides. A distinction between digoxin and digitoxin was not provided. Positive experiences have been reported for a long time for
openaire   +3 more sources

Dynamics of Cell Fate Decisions during Chemically Induced Multi‐Lineage Trans‐Differentiation at Single‐Cell Level

open access: yesAdvanced Science, Volume 12, Issue 17, May 8, 2025.
A critical aspect of chromosomal remodeling in small molecule‐induced multilineage trans‐differentiation(iMT) is elucidated. A dynamic atlas spanning over 35 days profiles terminal trans‐differentiated cells, which reverted to a more youthful state. This study reveals parallels between iMT and other cell fate determination processes, emphasizing an ...
Weigao E   +13 more
wiley   +1 more source

Digitoxin synergizes with sorafenib to inhibit hepatocelluar carcinoma cell growth without inhibiting cell migration.

open access: yesMolecular Medicine Reports, 2017
Sorafenib is a chemotherapeutic agent approved for the treatment of hepatocellular carcinoma (HCC) in China. Digitoxin is a cardiotonic drug, which has been demonstrated to exhibit anticancer effects in a number of cancers, but not in HCC. The aim of the
Yijun Xiao   +10 more
semanticscholar   +1 more source

Investigation of Relationship Between Chemical Stress Factors and Certain Metabolites Including Cardenolides in Callus Cultures of Endemic Turkish Digitalis L. Species

open access: yesInternational Journal of Secondary Metabolite, 2017
The aim of the present research is to obtain relationship between different stress treatments [Cu (copper) and Hg (mercury)] and content of cardiac glycosides (digoxigenin, gitoxigenin, lanatoside C, digoxin and digitoxin) as secondary metabolites of ...
Gunce Sahin   +2 more
doaj   +1 more source

OSWALD SCHMIEDEBERG –THE “FATHER” OF EXPERIMENTAL PHARMACOLOGY [PDF]

open access: yesResearch Results in Pharmacology, 2017
Biography. Oswald Schmiedeberg (1838-1921) was a son of a bailiff and a maid of honour, the eldest of the six children in the family. He was born and educated in the Russian Empire. Scientific activity. All his life he was completely devoted to science,
Mikhail Pokrovskii   +3 more
doaj   +3 more sources

An updated pharmacological insight into calotropin as a potential therapeutic agent in cancer

open access: yesFrontiers in Pharmacology, 2023
Calotropin is a pharmacologically active compound isolated from milkweed plants like Calotropis procera, Calotropis gigantea, and Asclepias currasavica that belong to the Asclepiadaceae family.
Jovana Rajkovic   +7 more
doaj   +1 more source

Nurses\u27 Alumnae Association Bulletin - Volume 16 Number 1 [PDF]

open access: yes, 1951
Alumnae Notes ANA Biennial Convention Cancer of the Cervix, Uterus and Ovaries Committee Reports Digest of Alumnae Association Meetings Greetings from Miss Childs Greetings from the President Graduation Awards - 1950 Isotopes and the Nurse - Dr.
Cantwell, Elsie B   +14 more
core   +1 more source

Investigation of the interaction between indigotin and two serum albumins by spectroscopic approaches [PDF]

open access: yes, 2013
The binding characteristics of indigotin with human serum albumin (HSA) and bovine serum albumin (BSA) have been investigated by various spectroscopic techniques.
Cheng, Zheng-Jun   +3 more
core   +2 more sources

Fluorescent Probe for δ‐Cyclodextrin Enables Guest Encapsulation Studies via an Indicator Displacement Assay

open access: yesChemistryEurope, Volume 3, Issue 3, May 2025.
A molecular probe that partially unfolds and exhibits fluorescence enhancement upon binding to δ‐cyclodextrin (δ‐CD) is presented. Its implementation in a fluorescence indicator displacement assay to test the binding of various guest to δ‐CD is demonstrated.
Mads G. Rasmussen   +7 more
wiley   +1 more source

Peruvoside, a Cardiac Glycoside, Induces Primitive Myeloid Leukemia Cell Death

open access: yesMolecules, 2016
Despite the available chemotherapy and treatment, leukemia remains a difficult disease to cure due to frequent relapses after treatment. Among the heterogeneous leukemic cells, a rare population referred as the leukemic stem cell (LSC), is thought to be ...
Qian Feng   +3 more
doaj   +1 more source

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