Results 71 to 80 of about 10,909 (272)

The mechanisms of Chansu in inducing efficient apoptosis in colon cancer cells [PDF]

open access: yes, 2013
Chansu is one of the most widely used traditional Chinese medicines in China, Japan, and other Southeast Asian countries primarily for antipain, anti-inflammation, and recently anticancer.
Cao, Siyu   +6 more
core   +3 more sources

The Renaissance of Digitoxin Is Overdue [PDF]

open access: yesDeutsches Ärzteblatt international, 2016
A 12-page review article on heart failure is very commendable (1). However, it is a source of irritation that in such a comprehensive article, a total of six lines is all that is given to the positive inotropic digitalis glycosides. A distinction between digoxin and digitoxin was not provided. Positive experiences have been reported for a long time for
openaire   +3 more sources

Peruvoside, a Cardiac Glycoside, Induces Primitive Myeloid Leukemia Cell Death

open access: yesMolecules, 2016
Despite the available chemotherapy and treatment, leukemia remains a difficult disease to cure due to frequent relapses after treatment. Among the heterogeneous leukemic cells, a rare population referred as the leukemic stem cell (LSC), is thought to be ...
Qian Feng   +3 more
doaj   +1 more source

OSWALD SCHMIEDEBERG –THE “FATHER” OF EXPERIMENTAL PHARMACOLOGY [PDF]

open access: yesResearch Results in Pharmacology, 2017
Biography. Oswald Schmiedeberg (1838-1921) was a son of a bailiff and a maid of honour, the eldest of the six children in the family. He was born and educated in the Russian Empire. Scientific activity. All his life he was completely devoted to science,
Mikhail Pokrovskii   +3 more
doaj   +3 more sources

Dynamics of Cell Fate Decisions during Chemically Induced Multi‐Lineage Trans‐Differentiation at Single‐Cell Level

open access: yesAdvanced Science, Volume 12, Issue 17, May 8, 2025.
A critical aspect of chromosomal remodeling in small molecule‐induced multilineage trans‐differentiation(iMT) is elucidated. A dynamic atlas spanning over 35 days profiles terminal trans‐differentiated cells, which reverted to a more youthful state. This study reveals parallels between iMT and other cell fate determination processes, emphasizing an ...
Weigao E   +13 more
wiley   +1 more source

Employment of artificial intelligence approach for optimizing the solubility of drug in the supercritical CO2 system

open access: yesCase Studies in Thermal Engineering
This paper investigates the solubility behavior of digitoxin in supercritical carbon dioxide (CO2) through a comprehensive analysis employing ensemble learning techniques and various regression models.
Meixiuli Li   +4 more
doaj   +1 more source

Investigation of Relationship Between Chemical Stress Factors and Certain Metabolites Including Cardenolides in Callus Cultures of Endemic Turkish Digitalis L. Species

open access: yesInternational Journal of Secondary Metabolite, 2017
The aim of the present research is to obtain relationship between different stress treatments [Cu (copper) and Hg (mercury)] and content of cardiac glycosides (digoxigenin, gitoxigenin, lanatoside C, digoxin and digitoxin) as secondary metabolites of ...
Gunce Sahin   +2 more
doaj   +1 more source

Combined amiodarone and digitalis therapy before heart transplantation is associated with increased post‐transplant mortality

open access: yesESC Heart Failure, 2020
Aims Amiodarone and digitalis are frequently used drugs in patients with heart failure. Both have separately been linked to reduced post‐transplant survival, but their combined impact on mortality after HTX remains uncertain.
Rasmus Rivinius   +9 more
doaj   +1 more source

Two-Step Preparation of Protein-Decorated Biohybrid Quantum Dot Nanoparticles for Cellular Uptake

open access: yesPharmaceutics, 2023
Decoration of nanoparticles with specific molecules such as antibodies, peptides, and proteins that preserve their biological properties is essential for the recognition and internalization of their specific target cells.
Agata Noelia Traverso   +10 more
doaj   +1 more source

Fluorescent Probe for δ‐Cyclodextrin Enables Guest Encapsulation Studies via an Indicator Displacement Assay

open access: yesChemistryEurope, Volume 3, Issue 3, May 2025.
A molecular probe that partially unfolds and exhibits fluorescence enhancement upon binding to δ‐cyclodextrin (δ‐CD) is presented. Its implementation in a fluorescence indicator displacement assay to test the binding of various guest to δ‐CD is demonstrated.
Mads G. Rasmussen   +7 more
wiley   +1 more source

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