Results 11 to 20 of about 45,447 (273)

Tackling the Reactivity of Propadiene: Palladium Metallaphotoredox Dual Catalyzed Multi-Component Allylation and Dienylation of Styrenes. [PDF]

open access: yesAngew Chem Int Ed Engl
We presented herein that propadiene can chemodivergently form either an allylic moiety or a dienylic moiety under Pd catalysis. Embedding this reactivity pattern into photocatalysis with DHP as the initial radical source and styrene derivatives as the initial acceptor leads to multi‐component allylation and dienylation.
Yang YF, Bauer F, Breit B.
europepmc   +3 more sources

Screening and Diagnosis of Primary Aldosteronism in Patients Using Renin-Angiotensin System Inhibitors. [PDF]

open access: yesJ Clin Hypertens (Greenwich)
ABSTRACT This study investigated whether patients receiving renin‐angiotensin system inhibitors (RASIs) can undergo reliable screening for primary aldosteronism (PA) without discontinuation of therapy. Consecutive patients with hypertension who underwent PA screening at our hospital between 2016 and 2024 while on RASIs were recruited.
Wang Q, Dong H, Li HW, Zou YB, Jiang XJ.
europepmc   +2 more sources

Diethyl 4-(3-chlorophenyl)-2,6-diphenyl-1,4-dihydropyridine-3,5-dicarboxylate

open access: yesIUCrData, 2019
In the title compound, C29H26ClNO4, the dihydropyridine ring adopts a shallow boat conformation. The mean plane of the dihydropyridine ring (all atoms) subtends dihedral angles of 66.54 (1), 73.71 (1) and 79.47 (1)° with the two phenyl rings and the ...
K. K. Mohammed Ameen   +3 more
doaj   +1 more source

MODULATION OF CALCIUM CHANNELS IN ARTERIAL SMOOTH-MUSCLE CELLS BY DIHYDROPYRIDINE ENANTIOMERS [PDF]

open access: yes, 1993
The actions of the optical enantiomers of BAY K 8644 and Sandoz 202,791 were studied on barium inward currents recorded using the whole-cell configuration of the patch clamp technique from enzymatically isolated smooth muscle cells from the rabbit ear ...
Bolton, TB   +3 more
core   +1 more source

Effects of dietary dihydropyridine supplementation on growth performance and lipid metabolism of broiler chickens

open access: yesCzech Journal of Animal Science, 2010
An experiment was conducted to investigate the effects of dihydropyridine supplementation on growth performance and lipid metabolism of broilers. A total of 480 one-day-old female Arbor Acres broiler chicks were randomly divided into four groups, each ...
Z.Y. Niu, F.Z. Liu, Y.N. Min, W.C. Li
doaj   +1 more source

Cardioprotective Effect against Ischemia–Reperfusion Injury of PAK-200, a Dihydropyridine Analog with an Inhibitory Effect on Cl but Not Ca2+ Current

open access: yesBiomolecules, 2023
We examined the effects of a dihydropyridine analog, PAK-200, on guinea pig myocardium during experimental ischemia and reperfusion. In isolated ventricular cardiomyocytes, PAK-200 (1 μM) had no effect on the basal peak inward and steady-state currents ...
Iyuki Namekata   +4 more
doaj   +1 more source

Photodegradation of nimodipine and felodipine in microheterogeneous systems [PDF]

open access: yes, 2012
Indexación: Web of Science; ScieloThe photochemical behavior of nimodipine (NIMO) and felodipine (FELO), photolabile drugs widely used as antihypertensive calcium channel blockers, is studied in constrained media.
Brito, Julio   +6 more
core   +1 more source

Recent Progresses in the Catalytic Stereoselective Dearomatization of Pyridines

open access: yesMolecules, 2023
1,2- and 1,4-dihydropyridines and N-substituted 2-pyridones are very important structural motifs due to their synthetic versatility and vast presence in a variety of alkaloids and bioactive molecules.
Lucrezia Margherita Comparini   +1 more
doaj   +1 more source

One-step synthesis of pyridines and dihydropyridines in a continuous flow microwave reactor [PDF]

open access: yes, 2013
The Bohlmann–Rahtz pyridine synthesis and the Hantzsch dihydropyridine synthesis can be carried out in a microwave flow reactor or using a conductive heating flow platform for the continuous processing of material. In the Bohlmann–Rahtz reaction, the use
Bagley, Mark C   +4 more
core   +2 more sources

Immunochemical detection of a lipofuscin-like fluorophore derived from malondialdehyde and lysine

open access: yesJournal of Lipid Research, 2001
The accumulation of fluorescent age pigment or lipofuscin is a frequently observed age-associated cellular alteration in a variety of postmitotic cells of many species. These pigments are observed within granules composed, in part, of damaged protein and
Satoshi Yamada   +9 more
doaj   +1 more source

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