Results 1 to 10 of about 3,148 (255)

Dihydropyrimidinones Against Multiresistant Bacteria [PDF]

Frontiers in Microbiology, 2022
The increase in bacterial resistance to antimicrobials has led to high morbidity and mortality rates, posing a major public health problem, requiring the discovery of novel antimicrobial substances.
Marisa Castro Jara, Marisa Castro Jara, Allison Carlos Assunção Silva, Marina Ritter, Adriana Fernandes da Silva, Carolina Lambrecht Gonçalves, Pedro Rassier dos Santos, Luciano Sisconetto Borja, Cláudio Martin Pereira de Pereira, Patrícia da Silva Nascente, Patrícia da Silva Nascente   +10 more
doaj   +5 more sources

Defect-rich MOF-303 as a dual acid–base heterogeneous catalyst for the one-pot Biginelli synthesis of dihydropyrimidinones [PDF]

Scientific Reports
Bifunctional MOF-303 (Al) exhibits promising catalytic activity for the Biginelli reaction. However, its intrinsic microporosity may hinder reactant and product diffusion and reducing efficiency. Introducing defects is crucial for enhancing its catalytic
Nuhaa Shaheed, Ahmad Shaabani
doaj   +5 more sources

The role of phosphotungstic acid in enhancing the catalytic performance of UiO-66 (Zr) and its applications as an efficient solid acid catalyst for coumarins and dihydropyrimidinones synthesis

Catalysis Communications, 2022
In recent study, we report a facile and easy technique for the synthesis phosphotungstic acid (PTA) with different weight contents (10, 25, 50 and 75 wt%) loaded on UiO-66 (Zr) as efficient and reusable catalysts for the preparation of coumarin and ...
Fares T. Alshorifi, Dina E. Tobbala, Salah M. El-Bahy, Mohamed A. Nassan, Reda S. Salama   +4 more
doaj   +3 more sources

Specific TLR4 Blocking Effect of a Novel 3,4-Dihydropyrimidinone Derivative [PDF]

Frontiers in Pharmacology, 2021
Background: Toll-like receptor 4 (TLR4) initiates both innate and adaptive immune responses, which plays an important protective role in self-defense mechanisms.
Mingqian Zhou, Yiqi Wang, Xiaoying Lin, Jieping Wan, Chengping Wen   +4 more
doaj   +3 more sources

Natural dolomitic limestone-catalyzed synthesis of benzimidazoles, dihydropyrimidinones, and highly substituted pyridines under ultrasound irradiation [PDF]

Beilstein Journal of Organic Chemistry, 2020
Natural dolomitic limestone (NDL) is employed as a heterogeneous green catalyst for the synthesis of medicinally valuable benzimidazoles, dihydropyrimidinones, and highly functionalized pyridines via C–N, C–C, and C–S bond formations in a mixture of ...
Kumar Godugu, Venkata Divya Sri Yadala, Mohammad Khaja Mohinuddin Pinjari, Trivikram Reddy Gundala, Lakshmi Reddy Sanapareddy, Chinna Gangi Reddy Nallagondu   +5 more
doaj   +4 more sources

Pyromellitic acid grafted to cross-linked LDH by dendritic units: An efficient and recyclable heterogeneous catalyst for green synthesis of 2,3-dihydro quinazoline and dihydropyrimidinones derivatives. [PDF]

Heliyon, 2023
In this work, using layered double hydroxide (LDH) inorganic substrate, melamine as binding agent and dendrimer G1 and also pyromellitic acid (PMA) organic catalytic agent a heterogeneous acid catalyst was designed and prepared.
Ghanbari N, Ghafuri H.
europepmc   +2 more sources

Solvothermal Synthesis of Multiple Dihydropyrimidinones at a Time as Inhibitors of Eg5 [PDF]

Molecules, 2021
Solvothermal synthesis of multiple dihydropyrimidinones at a time has been developed in inexpensive and green bio-based solvent lactic acid without any additional catalysts or additives.
Xiao-Qiang Jiang, Shi-Quan Chen, Yan-Fei Liu, Xin-Guang Pan, Dan Chen, Shi-Fan Wang   +5 more
doaj   +2 more sources

FeCl3∙6H2O/TMSBr-Catalyzed Rapid Synthesis of Dihydropyrimidinones and Dihydropyrimidinethiones under Microwave Irradiation [PDF]

Molecules, 2017
An efficient and practical protocol has been developed to synthesize dihydropyrimidinones and dihydropyrimidinethiones through FeCl3∙6H2O/TMSBr-catalyzed three-component cyclocondensation under microwave irradiation.
Fei Zhao, Xiuwen Jia, Pinyi Li, Jingwei Zhao, Jun Huang, Honglian Li, Lin Li   +6 more
doaj   +2 more sources

Optimization study and application of box-behnken model for probing eggshell supported transition metals based catalysts to synthesize hydrazone & dihydropyrimidinones. [PDF]

Sci Rep
Solid supported catalysts have several synthetic applications. Herein, finely ground eggshells were used as a solid support for the preparation of transition metal (Ni, Zn, Cu, Sn and Co) based catalysts to synthesize 2,4-dinitrophenylhydrazone (3) and ...
Perveen R, Latif F, Abbas M, Ayub K, Sarfaraz S, Saeed M, Rana S, Al-Rashida M, Nawaz MA, Hameed A.   +9 more
europepmc   +2 more sources

CuFe2O4 Magnetic Nanoparticles as Heterogeneous Catalysts for Synthesis of Dihydropyrimidinones as Inhibitors of SARS-CoV-2 Surface Proteins—Insights from Molecular Docking Studies [PDF]

Processes, 2023
In this study, we present the highly efficient and rapid synthesis of substituted dihydropyrimidinone derivatives through an ultrasound-accelerated approach. We utilize copper ferrite (CuFe2O4) magnetic nanoparticles as heterogeneous catalysts, employing
Sónia A. C. Carabineiro, G. B. Dharma Rao, Lakhwinder Singh, Anjaneyulu Bendi, Mozhgan Afshari   +4 more
openalex   +2 more sources