Natural Surfactant Mediated Synthesis of 4-Aryl Substituted 3,4-Dihydropyrimidinones
Asian Journal of Chemistry, 2023 Present work describes the synthesis of 4-aryl substituted 3,4-dihydropyrimidinones (DHPMs) using aqueous extract of pericarp of Sapindus trifoliatus fruit as a green catalyst.
Santosh Pore
openalex +3 more sources
Catalysis Communications, 2022 Carboxylic acid functionalized imidazolium based novel acidic ionic liquid [CEMIM][MSA] was synthesized using economically feasible raw materials under very mild condition.
Priyanka Patil +3 more
doaj +2 more sources
Bioorganic & Medicinal Chemistry Letters, 2013 The synthesis of racemic tetrahydrocurcumin- (THC-), tetrahydrodemethoxycurcumin- (THDC-) and tetrahydrobisdemethoxycurcumin- (THBDC-) dihydropyrimidinone (DHPM) analogues was achieved by utilizing the multi-component Biginelli reaction in the presence of copper sulphate as a catalyst.
Sarawalee Arunkhamkaew +4 more
openalex +3 more sources
Diverse Methods with Stereoselective Induction in the Asymmetric Biginelli Reaction [PDF]
MoleculesThe relevance of the asymmetric Biginelli reaction (ABR) has been increased in this century, due to the pharmacological application of its products. This review focuses predominantly on articles published in the period from 2015 to 2024 on asymmetric ...
Marcos Díaz-Fernández +5 more
doaj +2 more sources
Ultrasound Assisted One-pot Synthesis of Dihydropyrimidinones Using Holmium Chloride As Catalyst [PDF]
Journal of Sciences, Islamic Republic of Iran, 2015 A simple and green chemical procedure was reported for the synthesis of dihydropyrimidinones from various aldehydes, ethyl acetoacetate and urea or thiourea using holmium chloride as catalyst.
S. Kakaei, H. Sid Kalal, H. Hoveidi
doaj +1 more source
Dihydropyrimidinone Based Chromones as New α‐Glucosidase Inhibitors
ChemistrySelectAbstract This study assesses newly synthesized chromones with a 3,4‐dihydropyrimidin‐2(1H)‐one core at C‐3, combined with triazole derivatives for their antidiabetic potential. Compounds 5a and 5b showed strong inhibition of α ...
Kumara Swamy Taviti +6 more
openaire +2 more sources
Lithium-Acetate-Mediated Biginelli One-Pot Multicomponent Synthesis under Solvent-Free Conditions and Cytotoxic Activity against the Human Lung Cancer Cell Line A549 and Breast Cancer Cell Line MCF7 [PDF]
The Scientific World Journal, 2012 Various Biginelli compounds (dihydropyrimidinones) have been synthesized efficiently and in high yields under mild, solvent-free, and eco-friendly conditions in a one-pot reaction of 1,3-dicarbonyl compounds, aldehydes, and urea/thiourea/acetyl thiourea ...
Harshita Sachdeva, Diksha Dwivedi
doaj +4 more sources
O,S,Se-containing Biginelli products based on cyclic β-ketosulfone and their postfunctionalization [PDF]
Beilstein Journal of Organic ChemistryA one-pot three-component Biginelli synthesis of dihydropyrimidinones/thiones/selenones via acetic acid or solvent-free Yb(OTf)3-catalyzed tandem reaction of β-ketosulfone (dihydro-2H-thiopyran-3(4H)-one-1,1-dioxide), an appropriate urea, and ...
Kateryna V. Dil, Vitalii A. Palchykov
doaj +2 more sources
Multicomponent Biginelli's synthesis of 3,4-dihydropyrimidin-2(1H)-ones promoted by SnCl2.2H2O [PDF]
Journal of the Brazilian Chemical Society, 2004 The ability of SnCl2.2H2O as catalyst to promote the Biginelli three-component condensation reaction from a diversity of aromatic aldehydes, ethyl acetoacetate and urea or thiourea is described.
Russowsky Dennis +5 more
doaj +2 more sources
Antioxidant Compounds in the Treatment of Alzheimer's Disease: Natural, Hybrid, and Synthetic Products. [PDF]
Evid Based Complement Alternat Med, 2023 Alzheimer’s disease (AD) which is associated with cognitive dysfunction and memory lapse has become a health concern. Various targets and pathways have been involved in AD’s progress, such as deficit of acetylcholine (ACh), oxidative stress, inflammation, β‐amyloid (Aβ) deposits, and biometal dyshomeostasis.
Hatami M +5 more
europepmc +2 more sources