Results 41 to 50 of about 3,167 (267)

Sono-thermal oxidation of dihydropyrimidinones

Ultrasonics Sonochemistry, 2008
Combination of ultrasound and heat has been used for the oxidation of some ethyl 3,4-dihydropyrimidin-2(1H)-one-5-carboxylates to their corresponding ethyl pyrimidin-2(1H)-one-5-carboxylates by using potassium peroxydisulfate in aqueous acetonitrile. An ultrasonic probe of 24 kHz frequency has been used for this study.
Hamid Reza, Memarian, Asadollah, Farhadi
openaire   +2 more sources

Mechanochemistry: New Tools to Navigate the Uncharted Territory of “Impossible” Reactions

ChemSusChem, Volume 15, Issue 17, September 7, 2022., 2022
Mission impossible: Mechanosynthesis is erroneously perceived as an enabling tool for only making greener well‐known solution‐based processes. Modern mechanochemistry is, above all, an effective tool to open synthetic paths not accessible by following conventional and well‐known pathways already reported in the literature for the classical chemistry in
Federico Cuccu, Lidia De Luca, Francesco Delogu, Evelina Colacino, Niclas Solin, Rita Mocci, Andrea Porcheddu   +6 more
wiley   +1 more source

Silica-ZnCl 2 : An Efficient Catalyst for the Synthesis of 4-Methylcoumarins [PDF]

, 2013
Silica-ZnCl2 has been found to be an efficient and eco-friendly catalyst for the synthesis of substituted 4-methylcoumarins from ethyl acetoacetate and substituted phenols under “neat” conditions in an oil bath at 80°C.
Bandita Datta, ., De Luca, L., Mohamed Afzal Pasha, .   +2 more
core   +1 more source

Nano-ZrO2-Catalyzed Biginelli Reaction and the Synthesis of Bioactive Dihydropyrimidinones That Targets PPAR-γ in Human Breast Cancer Cells

Catalysts, 2023
Bioactive dihydropyrimidinones (DHPs) were designed and synthesized by a multicomponent Biginelli reaction. The reaction was catalyzed by the polarized surface of nano-zirconium dioxide with partial positive charge of 0.52e at the Zr center and a ...
Suresha N. Deveshegowda, Ji-Rui Yang, Zhang Xi, Omantheswara Nagaraja, Kashifa Fazl-Ur-Rahman, Bhanuprakash C. Narasimhachar, G. Sethi, Ganga Periyasamy, Mahendra Madegowda, S. Rangappa, V. Pandey, P. Lobie, B. Basappa   +12 more
semanticscholar   +1 more source

Mesoionic Carbene Cobalt Complexes as Multipurpose Catalyst Precursors for Hydrosilylation and Dihydropyrimidinone Synthesis

Helvetica Chimica Acta, Volume 104, Issue 12, December 2021., 2021
Abstract Metalation of CH2OH‐substituted triazolium salts with CoCl2 under basic conditions affords C,O‐bidentate chelating carbene Co(III) complexes (3a, 3b), while analogous phenyl‐substituted triazolium salts produce monodentate carbene Co(II) complexes (3c, 3d).
Simone Bertini, Martin Albrecht
wiley   +1 more source

Methyl 6-Methyl-1-(4-methylphenyl)-2-oxo-4-phenyl-1,2,3,4-tetrahydropyrimidine-5-carboxylate

Molbank, 2012
Methyl 6-methyl-1-(4-methylphenyl)-2-oxo-4-phenyl-1,2,3,4-tetrahydro-pyrimidine-5-carboxylate has been synthesized via the modified Biginelli reaction from benzaldehyde, p-tolylurea, and methyl acetoacetate, promoted with microwave irradiation and ...
Haiping Wang, Qing Chen, Qingjian Liu
doaj   +1 more source

New Anticancer 4-Aryldihydropyrimidinone-5-Carboxylates Targeting Hsp90. [PDF]

Chem Biol Drug Des
We report the computational design and early structure–activity relationship optimisation (SAR) studies on new anticancer 4‐aryldihydropyrimidinone‐5‐carboxylate derivatives as inhibitors of heat shock protein 90. Analogue 5d emerged as a useful hit compound, combining inhibition of colony formation in breast cancer cell lines with effective Hsp90 ...
Bordoni C, Elstow TZ, Brancale A, Clarkson RWE, Westwell AD.   +4 more
europepmc   +2 more sources

Microwave assisted Biginelli cyclocon densation for the synthesis of dihydropyrimidinones catalysed by H2SO4Clay NPs and their applications

Journal of Photochemistry and Photobiology, 2021
The Acid Modification of Bentonite clay (AMC) process was firstly reported and has been developed in one pot by ionic exchange of inorganic interlayer clay combined with different concentrations of acid (H2SO4) under Microwave irradiation.
B.S. Surendra, K. Shyam Prasad, T R Shashi Shekhar, A. A Jahagirdar, S C Prashantha, N. Raghavendra, K. Gurushantha, N. Basavaraju, K. Rudresha   +8 more
doaj   +1 more source

Deep Eutectic Solvents: The Organic Reaction Medium of the Century [PDF]

, 2016
This microreview summarizes the use of deep eutectic solvents (DESs) and related melts in organic synthesis. Solvents of this type combine the great advantages of other proposed environmentally benign alternative solvents, such as low toxicity, high ...
Abbott, Abbott, Abbott, Abbott, Abbott, Abbott, Abbott, Abo-Hamad, Amelio, Aparicio, Assanosi, Azizi, Azizi, Azizi, Azizi, Azizi, Azizi, Azizi, Azizi, Azizi, Azizi, Azizi, Azizi, Azizi, Azizi, Azizi, Azizi, Azizi, Bafti, Bakavoli, Beckman, Bednarz, Borse, Cao, Cardellini, Carriazo, Chahdoura, Chai, Chaskar, Chen, Chen, Constable, Cragg, Dai, Dai, Dai, Dai, Davey, De Oliveira Vigier, De Oliveira Vigier, De Santi, del Monte, Disale, Domínguez de María, Domínguez de María, Duan, Dupont, Durand, Díaz-Álvarez, Earle, Ferreira, Fischer, Francisco, Gambino, García, García-Verdugo, García-Álvarez, García-Álvarez, Gill, Gore, Gorke, Gu, Guajardo, Gupta, Hallet, Handy, Handy, Handy, Hari, Hawkins, Hayyan, Henderson, Hu, Hu, Ilgen, Ilgen, Imperato, Imperato, Imperato, Itoh, Jella, Jérôme, Karmakar, Kemeling, Keshavarzipour, Khandelwal, Krishnakumar, Kumar, Kus, Laird, Lavilla, Li, Li, Li, Li, Lindström, Liu, Liu, Liu, Lobo, Lobo, Lu, Macaev, Machida, Mahboub, Mallardo, Martins, Matsuda, Maugeri, Maugeri, Maugeri, Mobinikhaledi, Morales, More, Müller, Müller, Pace, Pal, Pandey, Patil, Pavia, Pawar, Pednekar, Pena-Pereira, Pena-Pereira, Peters, Phadtare, Phadtare, Pincock, Pérez, Pérez-Sánchez, Radošević, Rastogi, Reddy, Rodríguez-Álvarez, Ruß, Saberi, Sanap, Sanap, Santos, Sassone, Scholten, Serrano, Sheldon, Shuklov, Singh, Singh, Singh, Singh, Singh, Smith, Sonawane, Steinrück, Stepankova, Sunitha, Tanaka, Tang, Tang, Vidal, Vidal, Vidal, Wagle, Wang, Wang, Wang, Wang, Wang, Wang, Wasserscheid, Welton, Xia, Yadav, Yadav, Yadav, Yu, Zhang, Zhang, Zhang, Zhang, Zhang, Zhang, Zhao, Zhao   +192 more
core   +2 more sources

Efficient synthesis of dihydropyrimidinones via a three-component Biginelli-type reaction of urea, alkylaldehyde and arylaldehyde

Beilstein Journal of Organic Chemistry, 2013
A one-pot three-component synthesis of dihydropyrimidinones via a molecular iodine-catalyzed tandem reaction of simple readily available mono-substituted urea, alkylaldehyde, and arylaldehyde has been developed. The reaction proceeds with high chemo- and
Haijun Qu, Xuejian Li, Fan Mo, Xufeng Lin   +3 more
doaj   +1 more source