Results 61 to 70 of about 3,167 (267)

Novel Dihydropyrimidinones: Molecular Docking, Synthesis and Anti-Neoplastic Activity

Asian Journal of Chemistry, 2023
Recent years have showed great interest in the synthesis of pyrimidinone and its applications in medicinal chemistry. Chalcones were synthesized through the Claisen-Schmidt condensation reaction between substituted aldehydes and acetone in the presence ...
M. P. Toraskar, R. Chaure, S. Sontakke
semanticscholar   +1 more source

Comparison of Catalytic Effect of Alkali and Alkaline Earth Metals Hydrogen Sulfate: As the Promoter for an Efficient Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones under Solvent-Free Conditions [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2005
Alkali and alkaline earth metals hydrogen sulfate catalyzed the one-pot three component condensation reactions of aldehydes, 1,3-dicarbonyl compounds and urea or thiourea under solvent-free conditions leading to 3,4-dihydropyrimidin-2(1H)-ones in high ...
Ahmad Shaabani, Ayoob Bazgir, Sakineh Arab Ameri, Masoumeh Sharifi Kiasaraie, Sima Samadi   +4 more
doaj  

Sulfated Zirconia-Catalyzed Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones (DHPMs) Under Solventless Conditions: Competitive Multicomponent Biginelli vs. Hantzsch Reactions

Molecules, 2006
The catalytic ability of ZrO2/SO42- to promote solventless three-componentcondensation reactions of a diversity of aromatic aldehydes, urea or thoiurea and ethylacetoacetate was studied.
Guillermo Negrón-Silva, Eduardo González-Zamora, Victor H. Lara-Corona, Leticia Lomas-Romero, Deyanira Angeles-Beltrán   +4 more
doaj   +1 more source

Synthesis of Dihydropyrimidinones via Biginelli Reaction by Using Molecular Iodine as Environmentally Friendly Catalyst

IOP Conference Series: Earth and Environment
The synthesis of 3,4-dihydropyrimidine-2-ones has been the focus of much interest since they exhibited various biological activities with pharmacology potentials (antibacterial, antitumor, antiviral, and anti-inflammatory).
A. Fadlan, L. Pratama, Y. A. Ilfahmi, W. Seviani, H. Masitoh   +4 more
semanticscholar   +1 more source

Dihydropyrimidinones: Recent Synthetic and Pharmacological Perspectives with Special Focus on Colon Cancer

Journal of Pharmaceutical Research and Development, 2023
The most important heterocyclic complexes involved in the manufacture of DNA and RNA are dihydropyrimidines. Through multi-component synthetic procedures like the Biginelli reaction and the Hantzsch dihydropyridine reaction, they were created.
Saba Beigh, R. Saleem, A. H. Maghrabi, Eman H. Khalifa, Saima Mushtaq, M. Rehman, A. Wali   +6 more
semanticscholar   +1 more source

Biological Activity and Efficient Synthesis of 3, 4- Dihydropyrimidin-2-(1H)-one/thione Derivatives [PDF]

, 2023
The present study aimed to use a method for the synthesis of some 3, 4- dihydropyrimidin-2-(1H) - ones/thiones. The study tried to answer the question whether this reaction can be performed without solvent and with new catalyst or not.
Hatamjafari, Farhad
core   +1 more source

Synthesis and Antioxidant Activity of Novel Biginelli Adducts with Phenolic Fragments

Applied Sciences
In this work, eco-friendly ceric ammonium nitrate (CAN) and ferric chloride hexahydrate catalysts in ethanol/acetonitrile systems were used to efficiently synthesize novel dihydropyrimidinone (-thione) derivatives via the Biginelli reaction. The obtained
Olga V. Snastina, Erik R. Sabitov, Viktoria A. Kuricheva, Vladimir N. Koshelev   +3 more
doaj   +1 more source

An Efficient Synthesis of 5-Alkoxycarbonyl-4-aryl-3,4-dihydropyrimidin-2(1H)-ones Catalyzed by KSF Montmorillonite

Molecules, 2000
A mild and efficient catalytic method for synthesis of 5-alkoxycarbonyl-4-aryl-3,4- dihydropyrimidin-2(1H)-ones using KSF montmorillonite as catalyst is described.
Ziyi Zhang, Xianten Chen, Jinchang Ding, Haixia Lin   +3 more
doaj   +1 more source

Synthesis of pyrimidines, aromatic and heteroaromatic acids as Biginelli reaction catalysts [PDF]

, 2015
Aromatic as well as heteroaromatic acids were found to beexcellent catalysts for the Biginelli three component synthesisof dihydropyrimidinones. Benzoic acid, substituted benzoic acids, five- and six- membered heterocyclic acids can be used for this ...
Adnan, Muhammad, Ain Khan, Misbahul, Ain, Quratul, Amina, Humaira, Kanwal, Fareeha, Lin, Whei-Oh, Naeem Khan, Muhammad, Nazeer, Areesha, Perveen, Saima, Uzzaman, Ashar   +9 more
core  

EFFICIENT SODIUM SELENATE-CATALYZED SYNTHESIS OF 3,4-DIHYDRO-2(1H)-PYRIMIDINONES AND –THIONES UNDER SOLVENT-FREE CONDITIONS [PDF]

, 2009
Sodium selenate efficiently catalyzes the three-component Biginelli reaction of an aldehyde, a,β-keto ester and urea or thiourea under solvent-free conditions to afford the corresponding 3,4-dihydropyrimidin-2(1H)-ones or –thiones in excellent ...
Baghernejad, Bita, Heidari, Maryam, Hekmatshoar, Rahim, M. Heravi, Majid   +3 more
core   +2 more sources