Results 91 to 100 of about 2,730,714 (181)
Epoxyeicosatrienoic acid metabolism in arterial smooth muscle cells.
Journal of Lipid Research, 1995 Epoxyeicosatrienoic acids (EETs) are eicosanoids synthesized from arachidonic acid by the cytochrome P450 eposygenase pathway. The present studies demonstrate that 8,9-, 11,12-, and 14,15-EET are rapidly taken up by porcine aortic smooth muscle cells ...
X. Fang +3 more
doaj +1 more source
Journal of Neuroscience Research, Volume 103, Issue 11, November 2025.Inhibition of soluble epoxide hydrolase (sEH) exerts a neuroprotective effect in a collagenase‐induced hemorrhagic stroke model, likely by increasing EETs. This neuroprotection appears to be mediated, at least in part, by the regulation of antioxidant balance.
Ari Misael Martínez‐Torres +2 more
wiley +1 more source
Novel renal arachidonate metabolites
, 1988 Cells of the thick ascending limb of the loop of Henle (TALH) metabolize arachidonic acid (AA) via the cytochrome P450 monooxygenase system to biologically active products that are resolved into two peaks, P1 and P2, on reverse-phase HPLC.
CARROL M. A. +7 more
core +1 more source
Food Science &Nutrition, Volume 13, Issue 9, September 2025.We developed a high‐throughput anaerobic culture method (96‐well microplates + multilayer liquid sealing) to evaluate food effects on gut microbiota. Using this method, the fermented products of Pichia fermentans were found to boost Bifidobacterium abundance (4.6–5.6 × vs.
Xin‐Yue Liu +4 more
wiley +1 more source
Renal cytochrome P-450-dependent metabolism of arachidonic acid in cirrhotic rats
, 1991 : Cirrhosis was induced in Wistar-Kyoto rats by intragastric administration of carbon tetrachloride. Microsomes were obtained from the renal cortex and outer medulla and incubated with [14C]arachidonic acid (AA) (0.2-0.4 microCi) in the presence or ...
Abraham, N. G. +5 more
core +1 more source
Mass Spectrometry Reviews, Volume 44, Issue 3, Page 513-538, May/June 2025.Abstract Liquid chromatography paired with tandem mass spectrometry (LC‐MS/MS) is the gold standard in measurement of endocannabinoid concentrations in biomatrices. We conducted a systematic review of literature to identify advances in targeted LC‐MS/MS methods in the period 2017–2024.
Khalisa Amir Hamzah +3 more
wiley +1 more source
Identification of arachidonate epoxides/diols by capillary chromatography-mass spectrometry.
Journal of Lipid Research, 1995 The identification of epoxide regioisomers of arachidonic acid (EETs) as methyl esters is difficult because they coelute during gas chromatography and possess similar mass spectra.
M VanRollins, H R Knapp
doaj +1 more source
ELECTROPHORESIS, Volume 46, Issue 5-6, Page 305-315, March 2025.ABSTRACT Oxylipins are well‐known lipid mediators in various inflammatory conditions. Their endogenous concentrations range from low picomolar to nanomolar, and there are growing demands to determine their concentrations in low‐volume matrices for pathological studies, including blood, cerebrospinal fluids from animal disease models, infants, and ...
Bingshu He +5 more
wiley +1 more source
Bile Acid Induced Diarrhoea Pathophysiological and Clinical Aspects [PDF]
, 2008 A common cause for referral to gastroenterologists is chronic watery diarrhoea. Approximately 40% of these patients have idiopathic bile acid malabsorption (BAM) – a condition with unknown aetiology.
Bajor, Antal
core +1 more source
Plasma Vasoprotective Eicosanoid Concentrations in Healthy Greyhounds and Non‐Greyhound Dogs
Journal of Veterinary Internal Medicine, 2016 Background Hypertension and albuminuria often coexist in Greyhounds, suggesting generalized vascular dysfunction that could contribute to the development of a variety of diseases in this breed.
J.T. Martinez +7 more
doaj +1 more source