Results 41 to 50 of about 105,621 (227)

Lessons Learnt Delivering a Novel Infectious Diseases National Training Programme to Timor-Leste’s Primary Care Workforce

Annals of Global Health
Background and Objectives: Timor-Leste is a lower-middle-income country in Southeast Asia. To control the significant local threat from infectious diseases, it is imperative to strengthen the knowledge and practice capabilities of the primary care ...
Robert Hammond, Antonito Hornay Cabral, Jeremy Beckett, Xhian Meng Quah, Natarajan Rajaraman, Sanjay Mathew, Amrutha Gopalakrishnan, Mariano Pereira, Manuel Natercio Noronha, Bernardo Pinto, João de Jesus Arcanjo, Celia Gusmao dos Santos, Telma Joana Corte-Real de Oliveira, Ingrid Bucens, Charlotte Hall   +14 more
doaj   +1 more source

Exploratory Study of Autoantibody Profiling in Drug‐Induced Liver Injury with an Autoimmune Phenotype

Hepatology Communications, 2020
Drug‐induced liver injury (DILI) sometimes presents with an autoimmune hepatitis‐like phenotype (AI‐DILI), and it is challenging to distinguish it from de novo autoimmune hepatitis (AIH).
Craig Lammert, Chengsong Zhu, Yun Lian, Indu Raman, George Eckert, Quan‐Zhen Li, Naga Chalasani   +6 more
doaj   +1 more source

Bismuth subcitrate, metronidazole and tetracycline – a rare cause of drug-induced liver injury

European Journal of Case Reports in Internal Medicine, 2023
Drug-induced liver injury (DILI) is a liver condition caused by any drug or toxic substance. The spectrum of DILI manifestations can range from asymptomatic elevation of liver enzymes to acute liver failure.
Carina Silva, Susana Merim, Rita Sevivas, João Mota, Alexandra Leitão   +4 more
doaj   +1 more source

Tide level in time and frequency domains at Dili port: Characteristic feature of a Lorentz oscillator

Physics of Complex Systems, 2021
Tide level during one year in time-domain measured at Dili port (East Timor) is analyzed by the frequency spectrum with the Fast Fourier Transform (FFT), together with the autocorrelation function (AF).
Abelito Filipe Belo, Kenji Sasa, Jose Madeira Marques, Koichi Shimakawa   +3 more
doaj   +1 more source

The challenges facing road-side ‘m-Preneurs’ in leap-frogging the constraints of ICTs in DCs: A Nigerian case study [PDF]

, 2017
Studies have shown that the number of mobile telecommunications operators in Nigeria has been on the increase since the first Global System of Mobile Telecommunications (GSM) licence was granted to MTN (Mobile Telecommunications Network) in 2001 ...
Ojukwu , Dili
core  

Validity of ICD-9 and ICD-10 codes used to identify acute liver injury: a study in three European data sources [PDF]

, 2019
This is the peer reviewed version of the following article: Forns, J. [et al.]. Validity of ICD-9 and ICD-10 codes used to identify acute liver injury: a study in three European data sources. "Pharmacoepidemiology and drug safety", 6 Juny 2019, vol.
Cainzos Achirica, Miguel, Castellsagué, Jordi, Cortés Martínez, Jordi, Deltour, Nicole, Forns, Joan, Giner Soriano, Maria, Hallas, Jesper, Hellfritzsch, M, Jacquot, Emmanuelle, Morros Padrós, Rosa, Pladevall, Miquel, Poblador Plou, Beatriz, Pottegard, Anton, Prados Torres, Alexandra, Pérez Gutthann, Susana   +14 more
core   +6 more sources

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

Advanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang, Linghua Zeng, Kunkun Zou, Keying Lin, Fangting Yao, Jinglun Song, Shumeng Zhang, Hanshu Feng, Zhichao Yang, Chunlei Wang, Hongtao Diao, Xue Kong, Tengfei Pan, Joonki Kim, Tianqi Duo, Linqiang Li, Yu Bian   +16 more
wiley   +1 more source

Death and Liver Transplantation within Two Years of Onset of Drug-Induced Liver Injury [PDF]

, 2017
Drug-induced liver injury (DILI) is an important cause of death and indication for liver transplantation (fatality). The role of DILI in these fatalities ispoorly characterized particularly when fatalities occur > 26 weeks after DILI onset.
Anania, Andrade, Bjornsson, Chalasani, Fontana, Fontana, Fontana, Fontana, Gustot, Jalan, Karvellas, Lee, Lee, Martinez, Medina-Caliz, Olson, Ostapowicz, Robles-Diaz, Rockey, Stickel, Stravitz, Zimmerman   +21 more
core   +2 more sources

Liver‐Targeted Gallium‐Polyphenol Network by Disrupting the ROS/NETs/PANoptosis Axis for Precision Acute Liver Injury Therapy

Advanced Science, EarlyView.
ABSTRACT Acute liver injury (ALI), driven by diverse insults such as drug toxicity and ischemia‐reperfusion, poses a high mortality risk and lacks targeted therapies. While reactive oxygen species (ROS), neutrophil extracellular traps (NETs), and a coordinated cell death pathway PANoptosis have been implicated, their interplay as a unified pathogenic ...
Xiaopeng Cai, Jian He, Jingwen Deng, Ziwei Wang, Zhongshu Wu, Kaiyue Wang, Xiang Zheng, Zhenzhen Gao, Xi Ma, Shumei Wei, Xiangrong Hu, Yuan Ding, Weilin Wang, Min Zhou   +13 more
wiley   +1 more source

Management of drug-induced liver injury in people with HIV treated for tuberculosis: 2024 update

Southern African Journal of HIV Medicine
No abstract available.
Tom Boyles, Rebecca H. Berhanu, Neliswa Gogela, Hannah Gunter, Tamsin Lovelock, Ndiviwe Mphothulo, Arifa Parker, Helena Rabie, Lauren Richards, Phumla Sinxadi, Camilla Wattrus, Mahomed-Yunus Moosa   +11 more
doaj   +1 more source