Results 31 to 40 of about 1,772 (162)

A Simple, Proficient and Green Approach for the Synthesis of 1,8-Dioxo-octahydroxanthenes Catalyzed by Cerium(IV) Ammonium Nitrate in Aqueous Media

Orbital: The Electronic Journal of Chemistry, 2014
Various biologically important 1,8-dioxo-“octahydroxanthene derivatives” have been efficiently synthesized in excellent yields using catalytic amounts of cerium(IV) ammonium nitrate (CAN) in water.
Shitole Nana Vikram, Nana V. Shitole, Gopal K. Kakde   +2 more
doaj   +1 more source

A facile microwave assisted one-pot synthesis of novel 1-methylhexahydroquinazolin-5(6H)-ones and bis-1-methylhexahydroquinazolin-5(6H)-ones

Orbital: The Electronic Journal of Chemistry, 2011
Novel hexahydroquinazolin-5(6H)-ones 3a-j have been synthesized in good yields by the reaction of enaminones 2a-b with primary amines and formaldehyde under the influence microwaves.
Madhusudhan Saha, Enamul Karim, Jai Narain Vishwakarma, Rishanlang Nongkhlaw   +3 more
doaj   +1 more source

Electro‐Mediated Redox Functionalization of Conjugated 1,3‐Dienes

Advanced Synthesis &Catalysis, Volume 368, Issue 6, 17 March 2026.
This review aims at providing a comprehensive view of the emerging field of electro‐mediated functionalization of conjugated 1,3‐dienes, highlighting key developments, mechanistic insights, and remaining challenges. It highlights the efficient use of electron as the sole reagent to access highly substituted allylic compounds from simple and readily ...
Ophélie Montiège, Jean‐François Brière, Cédric Schneider, Hélène Beucher   +3 more
wiley   +1 more source

Regioselectivity in the multicomponent reaction of 5-aminopyrazoles, cyclic 1,3-diketones and dimethylformamide dimethylacetal under controlled microwave heating

Beilstein Journal of Organic Chemistry, 2012
The multicomponent reaction of 5-aminopyrazole derivatives with cyclic 1,3-dicarbonyl compounds and dimethylformamide dimethylacetal (DMFDMA) in DMF at 150 °C under controlled microwave heating afforded regioselectively 8,9-dihydropyrazolo[1,5-a ...
Kamal Usef Sadek, Ramadan Ahmed Mekheimer, Tahany Mahmoud Mohamed, Moustafa Sherief Moustafa, Mohamed Hilmy Elnagdi   +4 more
doaj   +1 more source

Easier, Safer, and Greener: Unlocking the Power of Solid Reagents in Organic Reactions by Mechanochemistry

ChemistryEurope, Volume 4, Issue 2, February 2026.
This review highlights the powerful synergy between mechanochemistry and solid reagents to replace hazardous substances traditionally used in organic synthesis. Such an approach offers a safer and more sustainable pathway for conducting organic reactions, with potential benefits in both reactivity and selectivity. The use of solid bases, acids, and gas
Adrien Gallego, Nicolas Pétry, Julien Pinaud, Olivia Giani, Frédéric Lamaty   +4 more
wiley   +1 more source

Exploring Isophorone‐Based Dienones: Comprehensive Insights Into Their Synthesis, Reactivity, and Diverse Applications

Journal of Chemistry, Volume 2026, Issue 1, 2026.
Isophorone is an important motif in synthetic organic chemistry, as it is highly reactive and can get involved in a diverse array of functional group transformations to access various synthetic intermediates and molecular targets. In this context, an important group of compounds is the conjugated or nonconjugated isophorone‐cored dienones, which are ...
M. Saeed Abaee, Mohammad M. Mojtahedi, Sohini Basu Roy   +2 more
wiley   +1 more source

Alum promoted synthesis of 2H-indazolo[2,1-b]phthalazinetrione derivatives in water

Orbital: The Electronic Journal of Chemistry, 2012
A new and efficient synthesis of 2H-indazolo[2,1-b]phthalazine-1,6,11(13H)-trione derivatives from the three-component condensation reaction of phthalhydrazide, dimedone, and aromatic aldehydes using alum [KAl(SO4)2.12H2O] as catalyst was ...
Balaji Rajendra Madje, Jagdish V. Bharad, Milind B. Ubale, Murlidhar S. Shingare   +3 more
doaj   +1 more source

Synthesis of Cyano-Benzylidene Xanthene Synthons Using a Diprotic Brønsted Acid Catalyst, and Their Application as Efficient Inhibitors of Aluminum Corrosion in Alkaline Solutions

Molecules, 2022
Novel cyano-benzylidene xanthene derivatives were synthesized using one-pot and condensation reactions. A diprotic Brønsted acid (i.e., oxalic acid) was used as an effective catalyst for the promotion of the synthesis process of the new starting xanthene–
Mohammed A. Amin, Gaber A. M. Mersal, Morad M. El-Hendawy, Abdallah A. Shaltout, Ali Badawi, Johan Boman, Adil A. Gobouri, Murat Saracoglu, Fatma Kandemirli, Rabah Boukherroub, Jacek Ryl, Mohamed E. Khalifa   +11 more
doaj   +1 more source

Catalytic Strategies for Amide‐Based Michael Additions: Advances and Perspectives

Journal of Chemistry, Volume 2026, Issue 1, 2026.
The Michael addition is a cornerstone transformation in organic synthesis, enabling efficient C–C and C–heteroatom bond formation. Traditionally, α,β‐unsaturated carbonyl compounds such as enones and esters have dominated as Michael acceptors, whereas α,β‐unsaturated amides remain underutilized due to their strong resonance stabilization and low ...
Muhammad Naufal, Elvira Hermawati, Ace Tatang Hidayat, Dadan Sumiarsa, Ika Wiani Hidayat, Jamaludin Al-Anshori, Tulika Banerjee   +6 more
wiley   +1 more source

Hsp90β‐Selective Inhibitors: Probing the Solvent‐Accessible Frontier

ChemMedChem, Volume 20, Issue 24, December 15, 2025.
The piperidinol ring of the KUNB106 scaffold (boxed in red) occupies the solvent‐exposed region of the Hsp90β ATP‐binding pocket, which provides a unique opportunity to optimize this region of the molecule. In the study disclosed herein, modifications such as CC bonds, heteroatoms, and three‐dimensionality result in improved inhibitors that further ...
Terin D’Amico, Michael A. Serwetnyk, Xiaozheng Dou, Ian Mersich, Deborah Barlow, Karen L. Houseknecht, John M. Streicher, Aktar Ali, Brian S. J. Blagg   +8 more
wiley   +1 more source