Results 21 to 30 of about 4,332 (163)

Effect of diosgenin on lipid metabolism in rats.

open access: yesJournal of Lipid Research, 1979
The purpose of this study was to determine whether diosgenin suppresses cholesterol absorption in rats, and to examine relevant changes in cholesterol and bile acid metabolism.
M N Cayen, D Dvornik
doaj   +1 more source

Bio-Assisted Synthesis of Reduced Graphene Oxide Nanosheets From Graphene Oxide: Promising and Efficient Cytotoxic and Antidiabetic Potency in In Vitro, Kinetic, and In Silico Models. [PDF]

open access: yesInt J Biomater
Green chemistry has recently made strides in the sustainable synthesis of next‐generation nanomaterials using reducing agents sourced from plants. Biocompatible conversion of reduced graphene oxide from graphene oxide nanomaterials is of particular interest in medical applications. The leaf extract of C.
Yadav M   +4 more
europepmc   +2 more sources

The Equilibria of Diosgenin–Phosphatidylcholine and Diosgenin–Cholesterol in Monolayers at the Air/Water Interface [PDF]

open access: yesThe Journal of Membrane Biology, 2016
Diosgenin (Dio) has shown many treatment properties, but the most important property is cytotoxic activity in cancer cells. In this study, we investigated monolayers of Dio, cholesterol (Ch), and phosphatidylcholine (PC) at the air/water interface. The measurements were carried with a Langmuir Teflon trough and a Nima 9000 tensiometer program.
Janicka, Katarzyna   +2 more
openaire   +2 more sources

Pharmacokinetic Analysis of Diosgenin in Rat Plasma by a UPLC-MS/MS Approach

open access: yesJournal of Analytical Methods in Chemistry, 2022
Diosgenin, a steroidal sapogenin, has attracted attention worldwide owing to its pharmacological properties, including antitumor, cardiovascular protective, hypolipidemic, and anti-inflammatory effects.
Pei Liu   +10 more
doaj   +1 more source

Diosgenin, a Novel Aldose Reductase Inhibitor, Attenuates the Galactosemic Cataract in Rats

open access: yesJournal of Diabetes Research, 2017
Objective. To seek efficient aldose reductase inhibitors (ARIs) with excellent in vitro and in vivo biological activities against rat galactosemic cataract. Methods.
Lixia Ji, Lixia Cheng, Zhihong Yang
doaj   +1 more source

Optimization of diosgenin extraction from Dioscorea deltoidea tubers using response surface methodology and artificial neural network modelling.

open access: yesPLoS ONE, 2021
IntroductionDioscorea deltoidea var. deltoidea (Dioscoreaceae) is a valuable endangered plant of great medicinal and economic importance due to the presence of the bioactive compound diosgenin. In the present study, response surface methodology (RSM) and
Romaan Nazir   +7 more
doaj   +1 more source

Hydroxylation of Diosgenin by Absidia coerulea [PDF]

open access: yesNatural Product Communications, 2010
Microbial transformation of diosgenin (1) using Absidia coerulea yielded five new polar metabolites, which were identified as (25 R)-spirost-5-en-3β,7β,12β,25α-tetrol (2), (25 S)-spirost-5-en-3β,7α,12β,25β-tetrol (3), (25 S)-spirost-5-en-3β,7β,12β,25β-tetrol (4), (25 R)-spirost-5-en-3β,7α,12β,25α-tetrol (5), and (25 R)-spirost-5-en-3β,7β,12β,24β ...
Ying, Zhao   +5 more
openaire   +2 more sources

A Method for Improving Microbial Conversion of Diosgenin and Separation and Identification of the Product

open access: yesFermentation, 2023
Diosgenin, a hydrolysis product from Dioscorea plants, can be used as a precursor of steroid drugs (e.g., progesterone, testosterone, and glucocorticoid).
Fangyuan Mou   +9 more
doaj   +1 more source

Diosgenin: An Updated Pharmacological Review and Therapeutic Perspectives

open access: yesOxidative Medicine and Cellular Longevity, 2022
Plants including Rhizoma polgonati, Smilax china, and Trigonella foenum-graecum contain a lot of diosgenin, a steroidal sapogenin. This bioactive phytochemical has shown high potential and interest in the treatment of various disorders such as cancer, diabetes, arthritis, asthma, and cardiovascular disease, in addition to being an important starting ...
Prabhakar Semwal   +14 more
openaire   +4 more sources

Lueyang Black‐Boned Chicken and Black Bean Soup Promoting the Acute Healing of Skin Wounds, Accompanying Special Flavor Substances

open access: yesFood Chemistry International, EarlyView.
ABSTRACT Animal protein and plant protein make the protein supplement more comprehensive and further optimize the nutritional structure of the national diet. In this study, a “dual protein” Lueyang black‐boned chicken and black bean soup (FS) was prepared.
Mengya Zhao   +6 more
wiley   +1 more source

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