Results 61 to 70 of about 4,332 (163)

De Novo Transcriptome Sequencing in Trigonella foenum-graecum L. to Identify Genes Involved in the Biosynthesis of Diosgenin

The Plant Genome, 2013
T L. (fenugreek) is a viable alternative for production of diosgenin because of its shorter growing cycle, lower production costs, and consistent yield and quality.
Kanak Vaidya, Arpita Ghosh, Vinay Kumar, Spandan Chaudhary, Navin Srivastava, Kalpesh Katudia, Tanushree Tiwari, Surendra K. Chikara   +7 more
doaj   +1 more source

Complex engineering of Solanum alkaloids structural diversity in Nicotiana benthamiana

Plant Biotechnology Journal, Volume 24, Issue 1, Page 328-345, January 2026.
Summary Transient expression in Nicotiana benthamiana offers a powerful and versatile platform for rapid production of complex specialized metabolites. Steroidal glycoalkaloids (SGAs) and steroidal saponins produced by members of the Solanaceae family are known for their diverse structures and activities including antimicrobial, anticancer, antiviral ...
Sachin A. Gharat, Adam Jozwiak, Ilana Rogachev, Elinor A. Sharon, Sagit Meir, Ashok P. Giri, Asaph Aharoni   +6 more
wiley   +1 more source

Effects of Diosgenin on Myometrial Matrix Metalloproteinase-2 and -9 Activity and Expression in Ovariectomized Rats

International Journal of Biological Sciences, 2011
Diosgenin, a traditional Yam extraction, has been used in hormone replacement for menopausal women. We aimed to investigate the influences of diosgenin administration upon the MMP-2 and -9 activity and expression and reproductive hormones of ...
Chi-Chen Chang, Tang-Ching Kuan, Yao-Yuan Hsieh, Ying-Jui Ho, Yu-Ling Sun, Chih-Sheng Lin
doaj  

Exploring the role of diosgenin in modulating RUNX1 and HIPK2 transcription to mitigate Primary Sjögren's Syndrome

Immunobiology
Background: Primary Sjögren's Syndrome (pSS) is a chronic autoimmune disease characterized by inflammation of the exocrine glands, resulting in symptoms like dry mouth and eyes.
Yiwei Pan, Lunquan Wei, Han Liu, Fang Wang, Minhua Wang, Meijia Li, Pengfei Cheng, Xing Yan   +7 more
doaj   +1 more source

Chinese Herbal Medicines for Diabetic Cardio‐Cerebrovascular Diseases: Key Bioactive Metabolites and Action Mechanisms

Journal of Nutrition and Metabolism, Volume 2026, Issue 1, 2026.
Currently, the global incidence of diabetes is increasing, particularly in populous developing regions. In China, over 290 million people are affected by diabetic cardio‐cerebrovascular diseases. These diseases account for more than 40% of deaths and impose a significant economic burden on both society and families.
Ying Su, Shuwen Luo, Wei Li, Cuicui Cheng, Wei Liu, Xinyu Yang, Zhen Xing, Eric Gumpricht   +7 more
wiley   +1 more source

Molecularly imprinted polymers for diosgenin [PDF]

, 2019
Diosgenin is steroid sapogenin used in therapies of many diseases such as breast cancer, cervix cancer, prostate cancer, certain forms of leukemia and in infertility therapy. Diosgenin is a precursor for production of other significant steroidal compounds such as dehydroepiandrosterone [1].
Ugrinov, Stefan, Đurđević, Mladen, Todorov, Miljana, Pešić, Miloš   +3 more
openaire  

Insights into diosgenin against inflammatory bowel disease as functional food based on network pharmacology and molecular docking

Heliyon
Inflammatory bowel disease (IBD) is a growing global health problem. IBD is commonly prevalent in Europe and America and the incidence rate in Asia is on the rise due to altered dietary structure.
Min Cai, Yangchen Mao, Wenjing Gao, Zhenzhen Wang, Jianwei Mao, Ruyi Sha   +5 more
doaj   +1 more source

Enrichment of canalicular membrane with cholesterol and sphingomyelin prevents bile salt-induced hepatic damage

Journal of Lipid Research, 1999
These studies were undertaken to characterize the role of plasma membrane cholesterol in canalicular secretory functions and hepatocyte integrity against intravenous taurocholate administration.
Ludwig Amigo, Hegaly Mendoza, Silvana Zanlungo, Juan Francisco Miquel, Attilio Rigotti, Sergio González, Flavio Nervi   +6 more
doaj   +1 more source

A Diosgenin Tetrasaccharide from Cestrum nocturnum

Zeitschrift für Naturforschung B, 1995
A new monodesmosidic spirostanol glycoside extracted from the fresh leaves of Cestrum nocturnum was identified as spirost-5-ene-3-ol, [3β,25R]-3-O-[{α-L-rhamnopyranosyl-(1→4)- α-L-rhamnopyranosyl-(1→2)}-α-L-rhamnopyranosyl-(1→4)-β-D-glucopyranoside. The name proposed for this saponin is nocturnoside B. The structure elucidation was done on the basis of
Viqar Uddin Ahmad, Fehmida T. Baqai, Roshan Ahmad   +2 more
openaire   +1 more source

Diosgenin from Dioscorea bulbifera: novel hit for treatment of type II diabetes mellitus with inhibitory activity against α-amylase and α-glucosidase.

PLoS ONE, 2014
Diabetes mellitus is a multifactorial metabolic disease characterized by post-prandial hyperglycemia (PPHG). α-amylase and α-glucosidase inhibitors aim to explore novel therapeutic agents.
Sougata Ghosh, Piyush More, Abhishek Derle, Ajay B Patil, Pramod Markad, Adersh Asok, Navanath Kumbhar, Mahemud L Shaikh, Boppana Ramanamurthy, Vaishali S Shinde, Dilip D Dhavale, Balu A Chopade   +11 more
doaj   +1 more source