Results 71 to 80 of about 4,332 (163)

THE EFFECT OF SIMULTANEOUS APPLICATION OF NITROGEN AND COPPER ON YIELD AND STEROIDAL SAPOGENIN PRODUCTION IN Trigonella foenum graecum L.

Acta Scientiarum Polonorum: Hortorum Cultus, 2017
Diosgenin (a steroidal saponin of fenugreek) has long been used as a raw substance for the manufacturing of steroid drugs. In order to evaluate the nutritional effect of different nitrogen (0, 50, 100, 150 and 200 kg ha-1) and copper (0, 10, 20 and 30 ...
Mostafakamal Shams, Behzad Haghighi, Ertan Yildirim, Vali Rabiei, Sezai Ercisli, Sirus Masiha, Ahmad Golchin   +6 more
doaj  

Diosgenin fromAllium albidum [PDF]

Chemistry of Natural Compounds, 1970
E. V. Kereselidze, T. A. Pkheidze, É. P. Kemertelidze   +2 more
openaire   +1 more source

Predicting the potential global distribution of diosgenin-contained Dioscorea species

Chinese Medicine, 2018
Background Diosgenin, mainly extracted from wild diosgenin-contained Dioscorea species, is a well-known starting material of steroidal and contraceptive drugs. However, due to large market demand and increasingly ecological damage, wild Dioscorea species
Liang Shen, Jiang Xu, Lu Luo, Haoyu Hu, Xiangxiao Meng, Xiwen Li, Shilin Chen   +6 more
doaj   +1 more source

Identification of genetic variants controlling diosgenin content in Dioscorea zingiberensis tuber by genome-wide association study

BMC Plant Biology
Background Diosgenin is an important steroidal precursor renowned for its diverse medicinal uses. It is predominantly sourced from Dioscorea species, particularly Dioscorea zingiberensis.
Shi xian Sun, Yanmei Li, Lu Jia, Shili Ye, Yunpeng Luan   +4 more
doaj   +1 more source

Role of diosgenin extracted from Helicteres isora L in suppression of HIV-1 replication: An in vitro preclinical study

Heliyon
Background: Diosgenin, an essential sapogenin steroid with significant biological implications, is composed of a hydrophilic sugar moiety intricately linked to a hydrophobic steroid aglycone.
Smita Rakshit, Ashwini More, Shraddha Gaikwad, Chandrabhan Seniya, Aniket Gade, Vijaykumar Yogesh Muley, Anupam Mukherjee, Kapil Kamble   +7 more
doaj   +1 more source

Diosgenin reverses posttraumatic stress disorder in mice by augmenting neurochemical release and inhibiting HPA axis dysfunction, oxidative stress, and neuroinflammation

Journal of Affective Disorders Reports
Post-traumatic stress disorder (PTSD) is a mental disorder linked to neurochemical, hypothalamic-pituitary-adrenal (HPA)-axis dysregulations, inflammatory and pro-oxidant challenges in response to traumatic events.
Benneth Ben-Azu, Olusegun G. Adebayo, Adaeze Adebesin, Kenneth C. Oparaji, Vivian O. Ojiakor, Gift C. Pender, Bensandy O. Odeghe, Noah A. Omeiza, Halimat A. Abdulrahim, Vivian Ezieshi, Glory Ighosotu, Emmanuel Omo-Odudu, Ekene I. Monye   +12 more
doaj   +1 more source

Microbial metabolism of diosgenin by a novel isolated Mycolicibacterium sp. HK‐90: A promising biosynthetic platform to produce 19‐carbon and 21‐carbon steroids

Microbial Biotechnology
Green manufacture of steroid precursors from diosgenin by microbial replacing multistep chemical synthesis has been elusive. It is currently limited by the lack of strain and degradation mechanisms.
Zhikuan Wang, Hailiang Qiu, Yulong Chen, Xuemin Chen, Chunhua Fu, Longjiang Yu   +5 more
doaj   +1 more source

The antioxidant activity of diosgenin, a plant steroid sapogenin, in C2C12 myoblasts is achieved by blocking mitochondrial ROS production

Applied Biological Chemistry
Diosgenin, a plant-derived steroid sapogenin, has been reported to have many health benefits, including antioxidant activity. Although oxidative stress is a major factor impeding the differentiation and homeostasis of skeletal muscles, its antioxidant ...
Cheol Park, Gi-Young Kim, Yung Hyun Choi
doaj   +1 more source

Containment of neuroimmune challenge by diosgenin confers amelioration of neurochemical and neurotrophic dysfunctions in ketamine-induced schizophrenia in mice

Brain Disorders
Inhibition of neuroinflammation through N-methyl-D-aspartate receptor (NMDAR) regulation can provide normalization of neurochemical homeostasis and neurotrophic support in the pathogenesis of psychiatric disorders with complex symptoms such as ...
Benneth Ben-Azu, Olusegun G. Adebayo, Aliance R. Fokoua, Jackson E. Onuelu, Jerome N. Asiwe, Emuesiri G. Moke, Itivere A. Omogbiya, Oghenemarho L. Okpara, Jennifer E. Okoro, Omadevuaye M. Oghenevwerutevwe, Christian I. Uruaka   +10 more
doaj   +1 more source

Bioengineering of Important Secondary Metabolites and Metabolic Pathways in Fenugreek (Trigonella foenum-graecum L.)

Journal of Medicinal Plants, 2010
Fenugreek (Trigonella foenum-graecum L.) has a long and respected history of medicinal uses in Middle East and Persian medicine. The hypocholesterolaemic and hypoglycaemic effects of fenugreek were attributed to its major steroidal sapogenin, diosgenin ...
A Mehrafarin, A Qaderi, Sh Rezazadeh, H Naghdi Badi, Gh Noormohammadi, E Zand   +5 more
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