Results 41 to 50 of about 1,001 (132)

Lipid‐Lowering Potential of Food Formulations Based on Culinary‐Treated Flours of Dioscorea bulbifera (Dana) in Obese and Hyperlipidemic Rats

open access: yesFood Safety and Health, Volume 4, Issue 1, Page 233-246, January 2026.
This graphical abstract highlights the nutritional management of obesity through food formulations based on the two varieties (white and black) of Dioscorea bulbifera yams that has undergone culinary treatments (boiling and braising). The results show that white Dioscorea bulbifera showed the best properties compared to black after the culinary ...
Fossouo Towa Patrik Florent   +6 more
wiley   +1 more source

Comparative Profiling of Capsicum frutescens and C. annuum Reveals Superior Bioactivities and Nutritional Advantages for Functional Food Applications

open access: yesFood Science &Nutrition, Volume 14, Issue 1, January 2026.
Systematic bioactivity profiling revealed C. frutescens demonstrated significantly superior radical scavenging capacity (DPPH IC50: 111.96 ± 3.24 μg/mL; 2.5‐fold enhancement, p < 0.001), enhanced broad‐spectrum antibacterial efficacy (zone diameters: 8–22 mm), and notable cytotoxic activity meeting NCI preliminary criteria (LC50: 29.24 ± 1.15 μg/mL ...
Shahin Akter   +4 more
wiley   +1 more source

Switchgrass Steroidal Saponins Reduce Fungal Disease but Decrease Yeast Fermentation Yield

open access: yesGCB Bioenergy, Volume 18, Issue 1, January 2026.
Yeast fermentation of switchgrass biomass is inhibited for certain genotypes, especially those with high concentrations of steroidal saponins that protect against fungal disease. Inhibition can be reversed through (1) ergosterol addition, (2) fermentation with the bacterium Zymonomas mobilis, or (3) in different collection years.
Acer VanWallendael   +11 more
wiley   +1 more source

NUTRITIONAL COMPOSITION OF DIOSCOREA HISPIDA FROM DIFFERENT LOCATIONS AROUND LEUSER ECOSYSTEM AREA

open access: yesJurnal Natural, 2018
Proximate analysis of Dioscorea hispida tubers, collected from five locations around Leuser ecosystem in Aceh Province, showed variations amongst samples.
Sitti Saleha   +5 more
doaj   +1 more source

Complex engineering of Solanum alkaloids structural diversity in Nicotiana benthamiana

open access: yesPlant Biotechnology Journal, Volume 24, Issue 1, Page 328-345, January 2026.
Summary Transient expression in Nicotiana benthamiana offers a powerful and versatile platform for rapid production of complex specialized metabolites. Steroidal glycoalkaloids (SGAs) and steroidal saponins produced by members of the Solanaceae family are known for their diverse structures and activities including antimicrobial, anticancer, antiviral ...
Sachin A. Gharat   +6 more
wiley   +1 more source

The Immune Microenvironment in Liver Cancer: From Analysis to Targeting

open access: yesAdvanced Science, Volume 12, Issue 47, December 18, 2025.
This review explores how smart nanomedicines overcome the immunosuppressive tumor microenvironment in liver cancer. It details targeted delivery strategies and immune reprogramming mechanisms, including remodeling abnormal physiology, modulating metabolism, and inducing immunogenic cell death. The article highlights the paradigm shift toward multimodal
Jiaming Lan   +5 more
wiley   +1 more source

Bioengineering of Important Secondary Metabolites and Metabolic Pathways in Fenugreek (Trigonella foenum-graecum L.)

open access: yesJournal of Medicinal Plants, 2010
Fenugreek (Trigonella foenum-graecum L.) has a long and respected history of medicinal uses in Middle East and Persian medicine. The hypocholesterolaemic and hypoglycaemic effects of fenugreek were attributed to its major steroidal sapogenin, diosgenin ...
A Mehrafarin   +5 more
doaj  

Soil properties and phytochemical analysis of spleen amaranth (Amaranthus dubius Mart. Ex Thell.) from Ankole and Teso sub‐regions of Uganda: Implications for management and prevention of hyperglycemia

open access: yesJSFA reports, Volume 5, Issue 12, Page 418-430, December 2025.
ABSTRACT Background The current authors reported a remarkably higher prevalence of hyperglycemia in Ankole than in the Teso sub‐region of Uganda, and Amaranthus dubius was documented among the frequently eaten leafy vegetables in both sub‐regions.
Caroline Asekenye   +3 more
wiley   +1 more source

Life Factors and Melanoma: From the Macroscopic State to the Molecular Mechanism

open access: yesAdvanced Science, Volume 12, Issue 43, November 20, 2025.
Melanoma, an aggressive skin cancer, arises from dynamic interactions between genetic, environmental, and lifestyle factors. This review explores how age, gender, obesity, diet, exercise, smoking, alcohol, UV exposure, circadian rhythms, and medications influence melanoma risk and progression.
Hanbin Wang   +4 more
wiley   +1 more source

Mechanism and role of regulated cell death in tumor immunity and immunotherapy

open access: yesCancer Communications, Volume 45, Issue 11, Page 1456-1495, November 2025.
Abstract Cancer immune checkpoint inhibitors (ICIs) have brought breakthroughs, but only about one‐third of cancer patients benefit from ICIs. In recent years, targeting non‐apoptotic regulated cell death (RCD) subtypes, such as ferroptosis, necroptosis, autophagy, cuproptosis, and pyroptosis, has emerged as a novel strategy in cancer therapy due to ...
Jingwen Hu   +4 more
wiley   +1 more source

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