Results 41 to 50 of about 6,693 (273)

Nephroprotective Effect of Diosmin against Cisplatin-Induced Kidney Damage by Modulating IL-1β, IL-6, TNFα and Renal Oxidative Damage

Molecules, 2023
Cisplatin (CP) is a platinum compound of the alkylating agent class that is used for the treatment of various types of cancer. However, CP treatments in cancer patients are accountable for nephrotoxicity, as it is a major adverse effect.
Tarique Anwer, Saeed Alshahrani, Ahmad M. H. Somaili, Abdullah H. Khubrani, Rayan A. Ahmed, Abdulmajeed M. Jali, Ayed Alshamrani, Hina Rashid, Yousra Nomeir, Mohammad Khalid, Mohammad Firoz Alam   +10 more
doaj   +1 more source

Antioxidant capacities of flavones and benefits in oxidative-stress related diseases [PDF]

, 2015
Flavonoids, a group of secondary metabolites widely distributed in the plant kingdom, have been acknowledged for their interesting medicinal properties.
Alves-Silva, Jorge M., Cardoso, Susana M., Catarino, Marcelo D., Pereira, Olívia R.   +3 more
core   +1 more source

HPLC microfractionation of flavones and antioxidant (radical scavenging) activity of Saccharum officinarum L. [PDF]

, 2008
The antioxidant activity of sugarcane (Saccharum officinarum L.) juice towards DPPH reagent was determined (EC50) and the main compounds with radical scavenging activity in juice and leaves extracts were identified by HPLC-UV/PAD analysis combined with ...
COLOMBO, Renata, LIRA, Tatiana O. de, VILA, Fabiana C., YARIWAKE, Janete H.   +3 more
core   +1 more source

Protective effect of diosmin against doxorubicin-induced nephrotoxicity

Saudi Journal of Biological Sciences, 2021
Doxorubicin (Dox) is an anthracycline antibiotic that is primarily used for treating various solid tumors including that of pulmonary, ovary, breast, uterine, cervix, and several blood cancers. However, nephrotoxicity associated with Dox treatment limits its clinical use.
Ali, Nemat, AlAsmari, Abdullah F., Imam, Faisal, Ahmed, Mohammad Z., Alqahtani, Faleh, Alharbi, Metab, AlSwayyed, Mohammed, AlAsmari, Fawaz, Alasmari, Mohammed, Alshammari, Abdulrahman, Fantoukh, Omer I., Alanazi, Mohammed M.   +11 more
openaire   +2 more sources

Fabrication of diosmin loaded food-grade bilayer nanoparticles with modified chitosan and soy peptides and antioxidant properties examination

Food Chemistry: X
Diosmin is a flavonoid derived from plants, possessing anti-inflammatory, antioxidant, antidiabetic, neuroprotective and cardiovascular protective properties. However, diosmin has low solubility in water, leading to low bioavailability. In this study, we
Sen Li, Tong Guan, Hongyan Lv, Yuwei Cai, Wanqing Cao, Ze Zhang, Hongdong Song, Hongwei Cao, Xiao Guan   +8 more
doaj   +1 more source

Synthesis, Spectral Characterization, and Biochemical Evaluation of Antidiabetic Properties of a New Zinc-Diosmin Complex Studied in High Fat Diet Fed-Low Dose Streptozotocin Induced Experimental Type 2 Diabetes in Rats

Biochemistry Research International, 2015
In view of the established antidiabetic properties of zinc, the present study was aimed at evaluating the hypoglycemic properties of a new zinc-diosmin complex in high fat diet fed-low dose streptozotocin induced experimental type 2 diabetes in rats ...
Veerasamy Gopalakrishnan, Subramanian Iyyam Pillai, Sorimuthu Pillai Subramanian   +2 more
doaj   +1 more source

Diosmin and Bromelain Stimulate Glutathione and Total Thiols Production in Red Blood Cells

Molecules, 2023
Diosmin and bromelain are bioactive compounds of plant origin with proven beneficial effects on the human cardiovascular system. We found that diosmin and bromelain slightly reduced total carbonyls levels and had no effect on TBARS levels, as well as ...
Lukasz Gwozdzinski, Joanna Bernasinska-Slomczewska, Anna Wiktorowska-Owczarek, Edward Kowalczyk, Anna Pieniazek   +4 more
doaj   +1 more source

Diosmin Protects Rat Retina from Ischemia/Reperfusion Injury [PDF]

Journal of Ocular Pharmacology and Therapeutics, 2012
Diosmin, a natural flavone glycoside, possesses antioxidant activity and has been used to alleviate ischemia/reperfusion (I/R) injury. The aim of this study was to clarify whether the administration of diosmin has a protective effect against I/R injury induced using the high intraocular pressure (IOP) model in rat retina, and to determine the possible ...
Nianting, Tong, Zhenzhen, Zhang, Yuanyuan, Gong, Lili, Yin, Xingwei, Wu   +4 more
openaire   +2 more sources

Diosmin Enhances the Anti-migration Activity of Curcumin Analog PGV-1 on Colorectal Cancer Cells

Indonesian Biomedical Journal
BACKGROUND: Diosmin enhances the cytotoxicity of Pentagamavunone-1 (PGV-1) in cancer cells. PGV-1 and diosmin are predicted to target several matrix metalloproteinases (MMPs) in metastatic cancer, including colorectal cancer, but the anti-migration ...
Muthi Ikawati, Rohmad Yudi Utomo, Novia Permata Hapsari, Edy Meiyanto, Chio Oka   +4 more
doaj   +1 more source

Quantitative Determination of Diosmin in Tablets by Infrared and Raman Spectroscopy

Molecules, 2022
Diosmin is widely used in the treatment of chronic venous diseases and hemorrhoids. Based on Raman and infrared reflection spectra of powdered tablets in the mid- and near-infrared regions and results of reference high-performance liquid chromatographic ...
Sonia Pielorz, Magdalena Węglińska, Sylwester Mazurek, Roman Szostak   +3 more
doaj   +1 more source