Results 41 to 50 of about 4,792 (197)

Is There a Difference in the Clinical Efficacy of Diosmin and Micronized Purified Flavonoid Fraction for the Treatment of Chronic Venous Disorders? Review of Available Evidence

Vascular Health and Risk Management, 2021
Michèle Cazaubon,1 Jean-Patrick Benigni,2 Marcio Steinbruch,3 Violaine Jabbour,4 Christelle Gouhier-Kodas4 1Private Vascular Specialist, Paris, France; 2Pedagogical Support Office, Faculty of Medicine Pitié-Salpétrière, Sorbonne University, Paris, France;
Cazaubon M, Benigni JP, Steinbruch M, Jabbour V, Gouhier-Kodas C   +4 more
doaj  

Citrus phenylpropanoids and defence against pathogens. Part I: Metabolic profiling in elicited fruits [PDF]

, 2016
Penicillium spp. are among the major postharvest pathogens of citrus fruit. Induction of natural resistance in fruits constitutes one of the alternatives to chemical fungicides.
Ballester Frutos, Ana Rosa, Bovy, A.G., De Vos, R.C.H., González-Candelas, Luis, Lafuente, María Teresa   +4 more
core   +1 more source

Effect of Diosmin on Selected Parameters of Oxygen Homeostasis

International Journal of Molecular Sciences, 2023
Chronic venous disease (CVD) is a condition characterized by functional disturbances in the microcirculation of the superficial and deep veins, affecting up to 30% of the global population. Diosmin, a phlebotropic drug, is commonly used in the treatment of CVD, and its beneficial effects have been described in numerous clinical studies.
Marcin Feldo, Magdalena Wójciak, Sławomir Dresler, Paweł Sowa, Bartosz J. Płachno, Dariusz Samborski, Ireneusz Sowa   +6 more
openaire   +4 more sources

Diosmin ameliorates LPS-induced depression-like behaviors in mice: Inhibition of inflammation and oxidative stress in the prefrontal cortex

Brain Research Bulletin
Diosmin is a flavone glycoside with a confirmed therapeutic effectiveness on the chronic venous disorders. In this paper, the classical mouse depression model induced by LPS was established to explore the effect of Diosmin on depression.
Jingwei Zhao, Mingming Zhang, Huamin Zhang, Ying Wang, Bingyu Chen, Jing Shao   +5 more
doaj   +1 more source

Antioxidant Potential of Diosmin and Diosmetin against Oxidative Stress in Endothelial Cells

Molecules, 2022
Phlebotropic flavonoids, including diosmin and its aglycone diosmetin, are natural polyphenols widely used in the prevention and treatment of chronic venous insufficiency (CVI).
Magdalena Wójciak, Marcin Feldo, Grzegorz Borowski, Tomasz Kubrak, Bartosz J. Płachno, Ireneusz Sowa   +5 more
doaj   +1 more source

Quantitative Determination of Diosmin in Tablets by Infrared and Raman Spectroscopy

Molecules, 2022
Diosmin is widely used in the treatment of chronic venous diseases and hemorrhoids. Based on Raman and infrared reflection spectra of powdered tablets in the mid- and near-infrared regions and results of reference high-performance liquid chromatographic ...
Sonia Pielorz, Magdalena Węglińska, Sylwester Mazurek, Roman Szostak   +3 more
doaj   +1 more source

Diosmin alleviates retinal edema by protecting the blood-retinal barrier and reducing retinal vascular permeability during ischemia/reperfusion injury.

PLoS ONE, 2013
Background and purposeRetinal swelling, leading to irreversible visual impairment, is an important early complication in retinal ischemia/reperfusion (I/R) injury.
Nianting Tong, Zhenzhen Zhang, Wei Zhang, Yating Qiu, Yuanyuan Gong, Lili Yin, Qinghua Qiu, Xingwei Wu   +7 more
doaj   +1 more source

Effects of Diosmin on Vascular Leakage and Inflammation in a Mouse Model of Venous Obstruction

Frontiers in Nutrition, 2022
At present, iliac vein compression syndrome (IVCS) plagues countless people, posing a significant economic and social burden. The progress of current IVCS-related research is slow owing to the limitations of animal models.
Junjie Zou, Dongping Yuan, Jin Yang, Yun Yu   +3 more
doaj   +1 more source

The role of phospholipid as a solubility- and permeability-enhancing excipient for the improved delivery of the bioactive phytoconstituents of Bacopa monnieri [PDF]

, 2016
In an attempt to improve the solubility and permeability of Standardized Bacopa Extract (SBE), a complexation approach based on phospholipid was employed.
Bobde, Yamini S, Dave, Vivek S., Dhore, Pradip W., Gupta, Deepak, Mack, Connor, Raut, Nishikant, Saoji, Suprit   +6 more
core   +2 more sources

Exploration of the Phytochemical and Antidiabetic Properties of Teucrium polium: A Natural Asset for Type 2 Diabetes Management

ChemistryOpen, EarlyView.
Teucrium polium shows antidiabetic activity with its phytochemical composition and biological activities. The essential oil is rich in carvacrol, thymol, γ‐terpinene, and o‐cymene, while the aqueous and hydroethanolic extracts are characterized by poliumoside, verbascoside, isorhamnetin‐3‐O‐rutinoside, and apigenin‐7‐rutinoside. Antioxidant activity is
Hajar El Ouadni, Aziz Drioiche, Fadoua El Makhoukhi, Omkulthom Al kamaly, Hannou Zerkani, Smail Amalich, Imane Tagnaout, Mohamed Radi, Yahya Cherrah, Touriya Zair, Katim Alaoui   +10 more
wiley   +1 more source