Results 41 to 50 of about 5,257 (240)

Effects of Diosmin on Vascular Leakage and Inflammation in a Mouse Model of Venous Obstruction

Frontiers in Nutrition, 2022
At present, iliac vein compression syndrome (IVCS) plagues countless people, posing a significant economic and social burden. The progress of current IVCS-related research is slow owing to the limitations of animal models.
Junjie Zou, Dongping Yuan, Jin Yang, Yun Yu   +3 more
doaj   +1 more source

Diosmin Enhances the Anti-migration Activity of Curcumin Analog PGV-1 on Colorectal Cancer Cells

Indonesian Biomedical Journal
BACKGROUND: Diosmin enhances the cytotoxicity of Pentagamavunone-1 (PGV-1) in cancer cells. PGV-1 and diosmin are predicted to target several matrix metalloproteinases (MMPs) in metastatic cancer, including colorectal cancer, but the anti-migration ...
Muthi Ikawati, Rohmad Yudi Utomo, Novia Permata Hapsari, Edy Meiyanto, Chio Oka   +4 more
doaj   +1 more source

Quantitative Determination of Diosmin in Tablets by Infrared and Raman Spectroscopy

Molecules, 2022
Diosmin is widely used in the treatment of chronic venous diseases and hemorrhoids. Based on Raman and infrared reflection spectra of powdered tablets in the mid- and near-infrared regions and results of reference high-performance liquid chromatographic ...
Sonia Pielorz, Magdalena Węglińska, Sylwester Mazurek, Roman Szostak   +3 more
doaj   +1 more source

Optimization of Lipid Nanoparticles by Response Surface Methodology to Improve the Ocular Delivery of Diosmin: Characterization and In-Vitro Anti-Inflammatory Assessment

Pharmaceutics, 2022
Diosmin is a flavonoid with a great variety of biological activities including antioxidant and anti-inflammatory ones. Its cytoprotective effect in retinal pigment epithelium cells under high glucose conditions makes it a potential support in the ...
Elide Zingale, Salvatore Rizzo, Angela Bonaccorso, Valeria Consoli, Luca Vanella, Teresa Musumeci, Angelo Spadaro, Rosario Pignatello   +7 more
doaj   +1 more source

Is There a Difference in the Clinical Efficacy of Diosmin and Micronized Purified Flavonoid Fraction for the Treatment of Chronic Venous Disorders? Review of Available Evidence

Vascular Health and Risk Management, 2021
Michèle Cazaubon,1 Jean-Patrick Benigni,2 Marcio Steinbruch,3 Violaine Jabbour,4 Christelle Gouhier-Kodas4 1Private Vascular Specialist, Paris, France; 2Pedagogical Support Office, Faculty of Medicine Pitié-Salpétrière, Sorbonne University, Paris, France;
Cazaubon M, Benigni JP, Steinbruch M, Jabbour V, Gouhier-Kodas C   +4 more
doaj  

Diosmin ameliorates LPS-induced depression-like behaviors in mice: Inhibition of inflammation and oxidative stress in the prefrontal cortex

Brain Research Bulletin
Diosmin is a flavone glycoside with a confirmed therapeutic effectiveness on the chronic venous disorders. In this paper, the classical mouse depression model induced by LPS was established to explore the effect of Diosmin on depression.
Jingwei Zhao, Mingming Zhang, Huamin Zhang, Ying Wang, Bingyu Chen, Jing Shao   +5 more
doaj   +1 more source

Antioxidant Potential of Diosmin and Diosmetin against Oxidative Stress in Endothelial Cells

Molecules, 2022
Phlebotropic flavonoids, including diosmin and its aglycone diosmetin, are natural polyphenols widely used in the prevention and treatment of chronic venous insufficiency (CVI).
Magdalena Wójciak, Marcin Feldo, Grzegorz Borowski, Tomasz Kubrak, Bartosz J. Płachno, Ireneusz Sowa   +5 more
doaj   +1 more source

Citrus phenylpropanoids and defence against pathogens. Part I: Metabolic profiling in elicited fruits [PDF]

, 2016
Penicillium spp. are among the major postharvest pathogens of citrus fruit. Induction of natural resistance in fruits constitutes one of the alternatives to chemical fungicides.
Ballester Frutos, Ana Rosa, Bovy, A.G., De Vos, R.C.H., González-Candelas, Luis, Lafuente, María Teresa   +4 more
core   +1 more source

The role of phospholipid as a solubility- and permeability-enhancing excipient for the improved delivery of the bioactive phytoconstituents of Bacopa monnieri [PDF]

, 2016
In an attempt to improve the solubility and permeability of Standardized Bacopa Extract (SBE), a complexation approach based on phospholipid was employed.
Bobde, Yamini S, Dave, Vivek S., Dhore, Pradip W., Gupta, Deepak, Mack, Connor, Raut, Nishikant, Saoji, Suprit   +6 more
core   +2 more sources

Recent Insights on Synthesis, Stability, and Complexities of Water‐in‐Oil Pickering Emulsion: From Theory to Applications

Food Frontiers, EarlyView.
It provides a conceeptual framework of the core components required for w/o PE development and various internal and external factors determining the emulsion stabilization. It also emphasizes the emerging application of w/o PE in diverse industrial use such as encapsulation and delivery, packaging, food, biomedical, etc.
Bibha Mishra A., Vidisha Tomer
wiley   +1 more source