Results 121 to 130 of about 55,716 (280)

Differential Regulation of the Ten-Eleven Translocation (TET) Family of Dioxygenases by O-Linked β-N-Acetylglucosamine Transferase (OGT)*

open access: yesJournal of Biological Chemistry, 2014
Background: TET proteins have been shown to target OGT to chromatin, but whether OGT regulates the TET proteins is not clear. Results: OGT regulates the subcellular localization and enzymatic activity of TET3 but not TET1 and TET2.
Qiao Zhang   +6 more
semanticscholar   +1 more source

The Emerging Role of Ten-Eleven Translocation 1 in Epigenetic Responses to Environmental Exposures. [PDF]

open access: yes, 2020
Mounting evidence from epidemiological studies and animal models has linked exposures to environmental factors to changes in epigenetic markers, especially in DNA methylation.
Brown, Anthony P, Ji, Hong, Zhu, Tao
core  

Biological functions controlled by manganese redox changes in mononuclear Mn-dependent enzymes [PDF]

open access: yes, 2017
Remarkably few enzymes are known to employ a mononuclear manganese ion that undergoes changes in redox state during catalysis. Many questions remain to be answered about the role of substrate binding and/or protein environment in modulating the redox ...
Richards, Nigel G. J., Zhu, Wen
core   +2 more sources

A yeast three-hybrid system that reconstitutes mammalian hypoxia inducible factor regulatory machinery [PDF]

open access: yes, 2008
Background: Several human pathologies, including neoplasia and ischemic cardiovascular diseases, course with an unbalance between oxygen supply and demand ( hypoxia).
Alcaide-German, ML   +4 more
core  

C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation

open access: yesCell, 2001
A. C. Epstein   +19 more
semanticscholar   +1 more source

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