Results 161 to 170 of about 14,175 (245)

Spectroscopy and crystallography define carotenoid oxygenases as a new subclass of mononuclear non-heme Fe^II enzymes. [PDF]

J Biol Chem
DeWeese DE, Everett MP, Babicz JT, Daruwalla A, Solomon EI, Kiser PD.   +5 more
europepmc   +1 more source

The return of metabolism: biochemistry and physiology of glycolysis

Biological Reviews, Volume 101, Issue 2, Page 751-803, April 2026.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning, Federica Agostini, Camila Caldana, Johannes Hartl, Matthias Heinemann, Markus A. Keller, Jan Lukas Krüsemann, Costanza Lamperti, Carole L. Linster, Steffen N. Lindner, Julia Muenzner, Jens Nielsen, Zoran Nikoloski, Bettina Siebers, Jacky L. Snoep, Hezi Tenenboim, Bas Teusink, Spencer J. Williams, Mirjam M. C. Wamelink, Markus Ralser   +19 more
wiley   +1 more source

Integration of epigenetics into ecotoxicology: insights and fundamental research needs

Biological Reviews, Volume 101, Issue 2, Page 826-847, April 2026.
ABSTRACT Epigenetics refers to heritable changes in genome function that occur without direct alterations to the DNA sequence. A multitude of environmental contaminants can influence the epigenetic marks of a genome. Changes of epigenetic marks including DNA methylation, histone modifications, and non‐coding RNAs can induce alterations at the gene ...
Albano Pinto, Jana Asselman, Patrícia Pereira, Joana Luísa Pereira   +3 more
wiley   +1 more source

Pan-Genomic and Phenotypic Characterisation of Petroleum Hydrocarbon Degradation by Pseudomonas Species. [PDF]

Environ Microbiol Rep
Guo X, Zhu S, Zhu N, Zhang S, Yang S, Luo G, Li H, Wang Y, Sun J, Ma B.   +9 more
europepmc   +1 more source

Beyond PD‐1: Mechanisms of Resistance to Checkpoint Blockade in Classical Hodgkin Lymphoma and Next‐Generation Immune Strategies

European Journal of Haematology, Volume 116, Issue 4, Page 357-367, April 2026.
ABSTRACT PD‐1 inhibitors have reshaped the treatment landscape of classical Hodgkin lymphoma, yet a substantial proportion of patients exhibit primary or acquired resistance driven by tumor‐intrinsic alterations, immunosuppressive microenvironmental signals, metabolic constraints, and EBV‐mediated modulation.
Santino Caserta, Enrica Antonia Martino, Mamdouh Skafi, Maria Eugenia Alvaro, Antonella Bruzzese, Nicola Amodio, Eugenio Lucia, Virginia Olivito, Caterina Labanca, Francesco Mendicino, Ernesto Vigna, Fortunato Morabito, Massimo Gentile   +12 more
wiley   +1 more source

A Structural Landscape Depiction of Dynamic Stability Centers of Local Structure in Protein Thermostability Engineering. [PDF]

Research (Wash D C)
Qiu X, Liu H, Song P, Cheng X, Wu W, He S, Wang W, Xu P, Tang H.   +8 more
europepmc   +1 more source

Melatonin and the Dental Pulp: A Scoping Review

International Endodontic Journal, Volume 59, Issue 4, Page 590-613, April 2026.
ABSTRACT Background In general medicine, melatonin is known to enhance wound healing and promote stem cell differentiation. Its potential relevance in endodontics, however, remains underexplored. Objectives This scoping review aimed to systematically assess the available evidence on the effects of melatonin (a) on dental pulp tissue and (b) on human ...
Jasmin Schäfer, Konrad Kleszczynski, Edgar Schäfer   +2 more
wiley   +1 more source

Comparative genomics of dominant members of the gut core microbiome of the bark beetle, Dendroctonus rhizophagus (Curculionidae: Scolytinae) reveals potential functional complementarity in the detoxification process. [PDF]

BMC Genomics
Vazquez-Ortiz K, Rivera-Orduña FN, Zúñiga G.   +2 more
europepmc   +1 more source

Decoding plant defense signaling using the defenseless mutant

New Phytologist, Volume 250, Issue 2, Page 1141-1156, April 2026.
Summary Can plants live without defenses? Mutant analysis in Arabidopsis thaliana has identified numerous regulators of biotic, abiotic, and hormone‐based defenses, but the redundancy among separate defense pathways remains unexplored. We constructed an Arabidopsis mutant, defenseless, lacking six canonical defense pathways using abi1‐1 (abscisic acid),
Bikash Baral, Mikael Brosché
wiley   +1 more source

BTG13-related metalloenzymes: Atypical non-heme iron-dependent dioxygenases with unusual coordination patterns and catalytic mechanisms. [PDF]

Eng Microbiol
Deng Z, Yuan Z, Luo Z, Rao Y.
europepmc   +1 more source