Results 61 to 70 of about 3,651 (206)
Rapid Communications in Mass Spectrometry, Volume 40, Issue 8, 30 April 2026.ABSTRACT Background Proteolytic processing is a fundamental post‐translational modification. Liquid chromatography–tandem mass spectrometry (LC–MS/MS) workflows are powerful for degradomic analyses but inherently sacrifice spatial information, a critical aspect for investigating biological systems such as aberrant extracellular matrix remodeling and ...
Mujia Jenny Li +8 more
wiley +1 more source
Фармакокинетика и ФармакодинамикаRelevance. The nerve growth factor (NGF), possessing neuroprotective and neuroregenerative properties, holds promise for the development of medications for the treatment of post-stroke conditions. At the Federal Research Center for Innovator and Emerging
P. Yu. Povarnina +4 more
doaj +1 more source
, 2014 Neurotoxicity refers to the direct or indirect effect of chemicals that disrupt the nervous system of humans or animals. Numerous chemicals can produce neurotoxic diseases in humans, and many more are used as experimental tools to disturb or damage the ...
Brust +15 more
core +2 more sources
Advanced Healthcare Materials, Volume 15, Issue 14, 10 April 2026.Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales +11 more
wiley +1 more source
The action of mimetic peptides on connexins protects fibroblasts from the negative effects of ischemia reperfusion [PDF]
, 2015 Connexins have been proposed as a target for therapeutic treatment of a variety of conditions. The main approaches have been by antisense or small peptides specific against connexins.
Becker, DL +3 more
core +1 more source
Antiischemic properties of the Trka-receptor agonist, the nerve growth factor 4-th loop mimetic
Фармакокинетика и Фармакодинамика, 2018 Resume. Relevance. One of the actual problems facing modern medical science is the study of mechanisms and the search for effective ways to activate tissue neovascularization.
E. S. Pekeldina +7 more
doaj +1 more source
Beyond Covalent Crosslinks: Applications of Supramolecular Gels [PDF]
, 2018 Traditionally, gels have been defined by their covalently cross-linked polymer networks. Supramolecular gels challenge this framework by relying on non-covalent interactions for self-organization into hierarchical structures.
Christoff-Tempesta, Ty +2 more
core +2 more sources
Cyclodextrin‐Amino Acid Conjugates: Synthesis and Pharmaceutical Applications
ChemistryEurope, Volume 4, Issue 4, April 2026.Cyclodextrins (CDs) can be combined with amino acids via host‐guest complexation or by covalent conjugation through various synthetic routes. The chemical modifications introduce structural versatility, multifunctionality, and biocompatibility, which are essential characteristics for designing effective, next‐generation pharmaceutical formulations ...
Andrea Cesari +2 more
wiley +1 more source
Binding studies of creatinine and urea on iron-nanoparticle [PDF]
, 2015 Kidney diseases are complicated and can be fatal. Dialysis and transplantation are the only survival solutions to the patients suffering from kidney failures.
Biswadip Banerji, Sumit Kumar Pramanik
core +1 more source
Cancer Nexus, Volume 2, Issue 2, April 2026.ABSTRACT Lipid nanoparticles (LNPs) represent the most clinically advanced platform for RNA delivery and have enabled major breakthroughs in vaccines and gene therapies. However, their broader application is still limited by inefficient extrahepatic delivery, immunogenicity, and insufficient control over tissue‐ and cell‐specific targeting. This review
Yu Han +5 more
wiley +1 more source