Results 91 to 100 of about 28,724 (253)

Genetic Mapping of Orofacial Traits Reveals a Single Genomic Region Associated With Differences in Multiple Parameters of Jaw Size Between Astyanax mexicanus Surface and Cavefish

Evolution &Development, EarlyView.
By performing a genetic association study in cave × surface fish F2 hybrids, we discovered that premaxilla width, dentary length, and maxillary length are all significantly associated with a region on Chromosome 13 containing 109 genes. ABSTRACT The regulation of bone size is a poorly understood and complex developmental process.
Amanda K. Powers, Alleigh Amaismeier, Kathryn Thiel, William Anyonge, Suzanne E. McGaugh, Tyler E. Boggs, Clifford J. Tabin, Joshua B. Gross   +7 more
wiley   +1 more source

Muramyl dipeptide mediated immunomodulation on monocyte subsets exerts therapeutic effects in a mouse model of Alzheimer’s disease [PDF]

, 2020
Adham Fani Malekia, Giulia Cisbania, Marie-Michèle Plante, Paul Préfontaine, Nataly Laflamme, Jean Gosselin, Serge Rivest   +6 more
openalex   +1 more source

A short peptide derived from late embryogenesis abundant proteins enhances acid tolerance in Escherichia coli via modulation of two‐component regulatory systems

The FEBS Journal, EarlyView.
Expression of the LEA‐K peptide in E. coli BL21 (DE3) improved bacterial viability under acidic stress (pH4), suggesting a protective function. RNA‐sequencing of LEA‐K‐expressing vs. non‐expressing cells revealed 283 differentially expressed genes (DEGs). In silico docking linked LEA‐K to two‐component systems (TCS) proteins (Rcs, BtsS/R, and EnvZ/OmpR)
Khaled Metwally, Shinya Ikeno
wiley   +1 more source

Regulation of Calcium Absorption in Caco-2 Cells by Aspartic Acid, Glutamic Acid and Their Glycine Dipeptides

Shipin gongye ke-ji
In order to investigate the mechanism of aspartic acid, glutamic acid and their glycine dipeptides on calcium ion uptake, the isothermal titration calorimetry technique, electrochemistry, and Caco-2 cell model combined with quantum mechanical calculation
Jiachen LIU, Yi LI, Yongqiang CHENG, Ning TANG   +3 more
doaj   +1 more source

Structural and functional dissection of the WH2/DAD motif of INF2, a formin linked to human inherited degenerative disorders

The FEBS Journal, EarlyView.
The INF2 WH2/DAD domain, composed of hydrophobic and basic regions, forms a single α‐helix in solution. The hydrophobic segment is essential for INF2 function, as its deletion disrupts actin dynamics and causes nuclear abnormalities, like those seen in pathogenic INF2 DID variants. In contrast, natural INF2 WH2/DAD variants found in patients with renal
Leticia Labat‐de‐Hoz, Laura Fernández‐Martín, Paula Morales, Isabel Correas, María Ángeles Jiménez, Miguel Angel Alonso   +5 more
wiley   +1 more source

Synthesis, Characterization and Antimicrobial activity of protected dipeptides and their deprotected analogs [PDF]

, 2015
Jatinder Gill, Simranjeet Singh, Nidhi Sethi   +2 more
openalex   +1 more source

Protein tandem repeats that produce frameshifts can generate new structural states and functions

The FEBS Journal, EarlyView.
We explored an alternative protein structure landscape by analyzing amino acid sequences from frameshifted tandem repeats—regions prone to frameshifts. These frameshifts, especially in short repeats, lead to more drastic changes than in non‐repetitive regions, often altering structure, function, localization, and potentially contributing to disease ...
Zarifa Osmanli, Gudrun Aldrian, Jeremy Leclercq, Theo Falgarone, Santiago M. Gómez Bergna, Denis N. Prada Gori, Andrew V. Oleinikov, Ilham Shahmuradov, Andrey V. Kajava   +8 more
wiley   +1 more source

High-sensitivity profiling of dipeptides in sauce-flavor Baijiu Daqu by chemical derivatization and ultrahigh-performance liquid chromatography coupled with high-resolution mass spectrometry

Food Chemistry: X
Dipeptides in sauce-flavor Baijiu Daqu are protein degradation products during the fermentation of Daqu, which are believed to play a crucial role in the flavor and quality of Baijiu.
Zixuan Wang, Liangqiang Chen, Fan Yang, Xiaolin Wang, Yang Hu, Ting Wang, Xin Lu, Jianjun Lu, Chunxiu Hu, Huabin Tu, Guowang Xu   +10 more
doaj   +1 more source

Crystal structure of plant γ‐glutamyl peptidase 1: implications for sulfur metabolism and secondary metabolite biosynthesis

The FEBS Journal, EarlyView.
The crystal structures of Arabidopsis thaliana γ‐glutamyl peptidase 1 (GGP1), including the covalent intermediate state, were determined. GGP1 is involved in both glutathione degradation in the primary metabolism and glutathione conjugate processing in the secondary metabolism of glucosinolate and camalexin biosynthesis.
Kosei Sone, Takehiro Ito, Hibiki Sawada, Chihaya Yamada, Toma Kashima, Akimasa Miyanaga, Naoko Ohkama‐Ohtsu, Shinya Fushinobu   +7 more
wiley   +1 more source

Contractile effects of bacterial cell walls, their enzymatic digests, and muramyl dipeptides on ileal strips from guinea pigs [PDF]

, 1982
Takuya Ogawa, S Kotani, M Tsujimoto, S. Kusumoto, Tetsuo Shiba, Seiichi Kawata, Kanae Yokogawa   +6 more
openalex   +1 more source