Results 51 to 60 of about 28,724 (253)

Making Blank Faces Expressive: Chemical Approaches to the Modification of Chemically Inert Peptides [PDF]

J Pept Sci
As an alternative to the conventional approach, which combines amino acid monomers in a one‐by‐one fashion to peptide derivatives, the chemical modification of existing peptides has attracted significant attention in recent years. However, such approaches generally target the reactive functional groups in cysteine and lysine residues, particularly in ...
Moriyama Y, Sada H, Nanjo T.
europepmc   +2 more sources

Higher‐Level Structural Classification of Pseudomonas Cyclic Lipopeptides through Their Bioactive Conformation

Advanced Science, EarlyView.
Solution structures of a series of cyclic lipodepsipeptides from Pseudomonas reveal that these specialized metabolites adopt left‐handed alpha helical conformations of only two types, being either ‘stapled’ or ‘catch‐pole’ helix. The particular modular distribution of the biosynthetic gene clusters is found to determine the extent of their conserved ...
Benjámin Kovács, Durga Prasad, Vic De Roo, Matthias Vanheede, Penthip Muangkaew, Annemieke Madder, Monica Höfte, René De Mot, Niels Geudens, José C. Martins   +9 more
wiley   +1 more source

The role of histidine dipeptides on postmortem acidification of broiler muscles with different energy metabolism

Poultry Science, 2021
It is generally held that the content of several free amino acids and dipeptides is closely related to the energy-supplying metabolism of skeletal muscles.
Giulia Baldi, Francesca Soglia, Luca Laghi, Adele Meluzzi,, Massimiliano Petracci   +4 more
doaj   +1 more source

Active site remodelling of a cyclodipeptide synthase redefines substrate scope

Communications Chemistry, 2022
Cyclodipeptide synthases (CDPSs) generate a wide range of cyclic dipeptides using aminoacylated tRNAs as substrates, however the substrate selection mechanism is not yet known.
Emmajay Sutherland, Christopher John Harding, Clarissa Melo Czekster   +2 more
doaj   +1 more source

Metastable hydrogels from aromatic dipeptides [PDF]

Chemical Communications, 2016
The dipeptides FF and FF-NH2 form metastable hydrogels upon sonication. The hydrogels show instantaneous syneresis upon mechanical contact.
M. P. Conte, N. Singh, I. R. Sasselli, B. Escuder, R. V. Ulijn   +4 more
openaire   +3 more sources

Easier, Safer, and Greener: Unlocking the Power of Solid Reagents in Organic Reactions by Mechanochemistry

ChemistryEurope, EarlyView.
This review highlights the powerful synergy between mechanochemistry and solid reagents to replace hazardous substances traditionally used in organic synthesis. Such an approach offers a safer and more sustainable pathway for conducting organic reactions, with potential benefits in both reactivity and selectivity. The use of solid bases, acids, and gas
Adrien Gallego, Nicolas Pétry, Julien Pinaud, Olivia Giani, Frédéric Lamaty   +4 more
wiley   +1 more source

Synthesis and Antifungal Activity of Fmoc-Protected 1,2,4-Triazolyl-α-Amino Acids and Their Dipeptides Against Aspergillus Species

Biomolecules
In recent years, fungal infections have emerged as a significant health concern across veterinary species, especially in livestock such as cattle, where fungal diseases can result in considerable economic losses, as well as in humans.
Tatevik Sargsyan, Lala Stepanyan, Henrik Panosyan, Heghine Hakobyan, Monika Israyelyan, Avetis Tsaturyan, Nelli Hovhannisyan, Caterina Vicidomini, Anna Mkrtchyan, Ashot Saghyan, Giovanni N. Roviello   +10 more
doaj   +1 more source

Comprehensive Dipeptide Analysis Revealed Cancer-Specific Profile in the Liver of Patients with Hepatocellular Carcinoma and Hepatitis

Metabolites, 2020
As the physical properties and functionality of dipeptides differ from those of amino acids, they have attracted attention in metabolomics; however, their functions in vivo have not been clarified in detail.
Hitoshi Ozawa, Akiyoshi Hirayama, Futaba Shoji, Midori Maruyama, Kumi Suzuki, Hisami Yamanaka-Okumura, Hiroshi Tatano, Yuji Morine, Tomoyoshi Soga, Mitsuo Shimada, Masaru Tomita   +10 more
doaj   +1 more source

Quantification of Histidine-Containing Dipeptides in Dolphin Serum Using a Reversed-Phase Ion-Pair High-Performance Liquid Chromatography Method [PDF]

, 2021
Momochika Kumagai, Sanae Kato, Nanami Arakawa, Mika Otsuka, Takahisa Hamano, Nobuyuki Kashiwagi, Akira Yabuki, Osamu Yamato   +7 more
openalex   +1 more source

Photoinduced Boron‐Catalyzed Direct α‐Aminoxylation of Carboxylic Acids

ChemistryEurope, EarlyView.
A boron‐catalyzed α‐aminoxylation of carboxylic acids enables rapid access to sterically congested α‐(aminoxy)carboxylic acids. Photoexcited diboron enediolates transfer energy to O‐sulfonylhydroxylamines, triggering SO bond cleavage to generate N‐oxyl radicals.
Tsubasa Oyama, Takuto Morisawa, Yukiho Yoshida, Yoshito Heike, Masaya Sawamura, Yohei Shimizu   +5 more
wiley   +1 more source