Results 141 to 150 of about 1,907 (195)

Interplay between diphenyl diselenide and copper: Impact on D. melanogaster survival, behavior, and biochemical parameters.

Comparative biochemistry and physiology. Toxicology & pharmacology : CBP
Copper (Cu2+) is a biologically essential element that participates in numerous physiological processes. However, elevated concentrations of copper have been associated with cellular oxidative stress and neurodegenerative diseases.
G.S. Rieder, T. Duarte, C. Delgado, A. Rodighiero, P. Nogara, L. Orian, M. Aschner, C. D. Dalla Corte, J. da Rocha   +8 more
semanticscholar   +1 more source

Diphenyl diselenide and diphenyl ditelluride: neurotoxic effect in brain of young rats, in vitro

Molecular and Cellular Biochemistry, 2010
This study examined whether maturity of rat brain may be relevant for the sensitivity to diphenyl diselenide (PhSe)(2) and diphenyl ditelluride (PhTe)(2) on [(3)H]glutamate uptake and release, in vitro. Brain synaptosomes were isolated from young (14- and 30-day-old) and adult rats and incubated at different concentrations of (PhSe)(2) or (PhTe)(2 ...
Ana Cristina Guerra, Souza, Eluza Curte, Stangherlin, Ana Paula, Ardais, Cristina Wayne, Nogueira   +3 more
openaire   +2 more sources

4,4'-Dichloro-diphenyl diselenide modulated oxidative stress that affected differently peripheral tissues in streptozotocin-exposed mice.

Canadian Journal of Physiology and Pharmacology, 2021
Streptozotocin (STZ) is a substance used experimentally to induce a diabetes model, a metabolic disease associated with oxidative tissue damage. This study evaluated if dichloro-diphenyl diselenide (p-ClPhSe)2 modulates oxidative stress in peripheral ...
L. S. Marques, V. A. Zborowski, S. O. Heck, B. Fulco, C. W. Nogueira   +4 more
semanticscholar   +1 more source

2,4-Diphenyl-1,3,2,4-diselenadiphosphetane 2,4-diselenide

2007
[122039-27-4] C12H10P2Se4 (MW 532.00) InChI = 1S/C12H10P2Se4/c15-13(11-7-3-1-4-8-11)17-14(16,18-13)12-9-5-2-6-10-12/h1-10H InChIKey = GKYFQRQKPYPLGJ-UHFFFAOYSA-N (reagent for the respective preparation of selenoamides2, 3 and selenocarboxylates4 from amides and carboxylic acids) Alternate Name: Woollins's reagent.
Etzer Darout, Spencer Knapp
openaire   +1 more source

Spinal mechanisms of antinociceptive action caused by diphenyl diselenide

Brain Research, 2007
The present study was designed to investigate further the mechanisms involved in the antinociception caused by diphenyl diselenide in behavioral model of pain in mice. Diphenyl diselenide (1-100 mg/kg), given orally, produced significant inhibition of the biting behavior induced by intrathecal (i.t.) injection of glutamate (175 nmol/site) and N-methyl ...
Lucielli, Savegnago, Larissa G, Pinto, Cristiano R, Jesse, João B T, Rocha, Cristina W, Nogueira, Gilson, Zeni   +5 more
openaire   +2 more sources

In-vitro Interactions between Fluconazole and Diphenyl Diselenide against Various Candida Species

Current Bioactive Compounds
In the immunocompromised population, Candida species are the most aetiologic agents causing severe nosocomial fungal infections. Candida species, irrespective of being commensals in the human microbiome, are the fourth most prevalent source of ...
Sweety Dahiya, Anil Kumar Chhillar
semanticscholar   +1 more source

Diphenyl diselenide and diphenyl ditelluride affect the rat glutamatergic system in vitro and in vivo

Brain Research, 2001
The aim of this study was to investigate the possible involvement of the glutamatergic system in the toxicity of organochalcogens, since this is an important neurotransmitter system for signal transduction and neural function. The results indicated that 100 microM diphenyl diselenide (PhSe)(2) and diphenyl ditelluride (PhTe)(2) inhibit by 50 and 70 ...
C W, Nogueira, L N, Rotta, M L, Perry, D O, Souza, J B, da Rocha   +4 more
openaire   +2 more sources

Novel Diselenide Bis-Schiff bases tagged with diphenyl ethers: Promising candidates for selective treatment of hypopharyngeal and breast adenocarcinoma.

Bioorganic chemistry (Print)
Organoselenium (OSe) compounds have received much attention due to their potential to inhibit tumor growth while also protecting cells from oxidative damage, making them promising cancer prevention agents.
Mohamed M. Hammouda, S. Shaaban, Hussein Ba-Ghazal, A. Dawood, Mohamed A Zeidan, A. A. Al Khatib, F. Alatawi, Khadra B. Alomari, Marwa M. Sharaky, Mohamed Alaasar, A. Al-karmalawy   +10 more
semanticscholar   +1 more source

(Diacetoxyiodo)benzene mediated metal-free C(sp2)-H phenylselenation of imidazo[1,2-a]pyridines and imidazo[2,1-b]thiazoles using diphenyl diselenide

ARKIVOC, 2021
Metal-free (diacetoxy)iodobenzene-mediated C( sp 2 )-H phenylselenation of imidazo[1,2-a ]pyridines and imidazo[2,1-b ]thiazoles using diphenyl diselenide has been developed.
Imran A. Opai, Prakash D. Shirsath, Amit H. Kalbandhe, N. Karade   +3 more
semanticscholar   +1 more source

Diphenyl Diselenide-Loaded Nanocapsules: Preparation and Biological Distribution

Applied Biochemistry and Biotechnology, 2013
Over the past years, organoselenium compounds have been aimed as targets of interest in organic synthesis. Diphenyl diselenide [(PhSe)2] is an important example of this class showing several pharmacological properties. However, the poor water-solubility and its low oral bioavailability may be considered an obstruction for the clinical utility of this ...
Camila F A, Giordani, Diego, de Souza, Luciano, Dornelles, Cristina W, Nogueira, Marta P, Alves, Marina, Prigol, Oscar E D, Rodrigues   +6 more
openaire   +2 more sources