Results 141 to 150 of about 63,745 (188)

Genotoxicity of diphenyl diselenide in bacteria and yeast

Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 2004
Diphenyl diselenide (DPDS) is an electrophilic reagent used in the synthesis of a variety of pharmacologically active organic selenium compounds. This may increase the risk of human exposure to the chemical at the workplace. We have determined its mutagenic potential in the Salmonella/microsome assay and used the yeast Saccharomyces cerevisiae to assay
Renato Moreira, Rosa, Krisley, Sulzbacher, Jaqueline Nascimento, Picada, Rafael, Roesler, Jenifer, Saffi, Martin, Brendel, João Antonio Pêgas, Henriques   +6 more
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Antisecretory and antiulcer effects of diphenyl diselenide

Environmental Toxicology and Pharmacology, 2006
The antisecretory and antiulcer effects of diphenyl diselenide were studied in vivo and in vitro. Diphenyl diselenide, administered intraperitoneally prevented the development of gastric lesions induced by ethanol and indomethacin. There was no difference in plasma uric acid concentrations in diphenyl diselenide-treated rats with gastric lesions ...
Lucielli, Savegnago, Marcio, Trevisan, Diego, Alves, Joao Batista Teixeira, Rocha, Cristina W, Nogueira, Gilson, Zeni   +5 more
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Enthalpy of combustion of diphenyl diselenide

The Journal of Chemical Thermodynamics, 1980
Abstract The standard enthalpy of the combustion reaction ( C 6 H 5 ) 2 Se 2( c )+16.5 O 2 ( g )+2263 H 2 O(l) =12 CO 2 ( g )+2{ SeO 2 +1134 H 2 O }( l ) has been measured in a rotating-bomb combustion calorimeter to be ΔHco = − (615.3 ± 2.8) kJ mol−1. This leads to a standard
C.T Mortimer, Janette Waterhouse
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Diphenyl diselenide changes behavior in female pups

Neurotoxicology and Teratology, 2006
Diphenyl diselenide, (PhSe)(2), is an organoselenium compound that affects a number of neuronal processes. The effect of maternal subcutaneous (s.c.) injection of 25 mg/kg (PhSe)(2) once daily during early postnatal development (from PND 1 to 21) was evaluated in offspring of Wistar rats.
Alexandre M, Favero, Simone N, Weis, Gilson, Zeni, João B T, Rocha, Cristina W, Nogueira   +4 more
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Teratogenic effects of diphenyl diselenide in Wistar rats

Reproductive Toxicology, 2005
Diphenyl diselenide is an organoselenium compound with potential therapeutic use. The present study evaluates the effects of single maternal subcutaneous injection of 50 and 100mg/kg diphenyl diselenide [(PhSe)2] at gestational days (GD) 6, 10 or 17 in Wistar rats. The highest dose of (PhSe2 was also administered at GD 7-12. External and internal fetal
Alexandre M, Favero, Simone N, Weis, Eluza C, Stangherlin, Gilson, Zeni, Joao B T, Rocha, Cristina W, Nogueira   +5 more
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Anti-inflammatory and antinociceptive activity of diphenyl diselenide

Inflammation Research, 2003
Ebselen, an organoselenium compound is able to modulate the inflammatory response in rodents. In the present study, the anti-inflammatory and antinociceptive activity of diaryl diselenides and ebselen was studied.Adult male Wistar rats and albino mice were treated with diaryl diselenides and ebselen in different doses.Carrageenin-induced paw edema ...
C W, Nogueira, E B, Quinhones, E A C, Jung, G, Zeni, J B T, Rocha   +4 more
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General AMBER Force Field Parameters for Diphenyl Diselenides and Diphenyl Ditellurides

The Journal of Physical Chemistry A, 2016
The General AMBER Force Field (GAFF) has been extended to describe a series of selenium and tellurium diphenyl dichalcogenides. These compounds, besides being eco-friendly catalysts for numerous oxidations in organic chemistry, display peroxidase activity, i.e., can reduce hydrogen peroxide and harmful organic hydroperoxides to water/alcohols and as ...
TORSELLO, MAURO, Pimenta, Antonio, WOLTERS, LANDO PETER, Moreira, Irina S., ORIAN, LAURA, POLIMENO, ANTONINO   +5 more
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Effects of diphenyl and p-chloro-diphenyl diselenides on feeding behavior of rats

Psychopharmacology, 2015
The searching for safe and effective antiobesity drugs has been the subject of intense research. Previous studies have shown several pharmacological applications of organoselenium compounds; however, their possible anorectic-like actions have not been investigated.This study aims to investigate the effects of (PhSe)2 and (p-ClPhSe)2 on feeding behavior
Cristiani F, Bortolatto, Suélen O, Heck, Bibiana M, Gai, Vanessa A, Zborowski, José S S, Neto, Cristina W, Nogueira   +5 more
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PREPARATION OF SYMMETRICAL SUBSTITUTED DIPHENYL DISELENIDES

Phosphorus, Sulfur, and Silicon and the Related Elements, 1994
Abstract The preparations of 254 known title compounds are fully documented and the 27 different synthetic methods for their preparation are discussed in detail.
Michael Ankersen, Steven R. Wilson
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Thermal and photochemical reactions of organocobaloximes with diphenyl disulphide and diphenyl diselenide

Journal of the Chemical Society, Perkin Transactions 2, 1981
Alkyl- and benzyl-bis(dimethylglyoximato)pyridinecobalt(III) complexes react with diphenyl disulphide or diphenyl diselenide, thermally and photochemically, to give good yields of alkyl or benzyl phenyl sulphides or selenides. Chiral alkylcobalt(III) complexes react to give racemic alkyl phenyl sulphides or selenides.
Jean Deniau, Kiem N. V. Duong, Alain Gaudemer, Peter Bougeard, Michael D. Johnson   +4 more
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