Results 151 to 160 of about 63,745 (188)

2,4-Diphenyl-1,3,2,4-diselenadiphosphetane 2,4-diselenide

2007
[122039-27-4] C12H10P2Se4 (MW 532.00) InChI = 1S/C12H10P2Se4/c15-13(11-7-3-1-4-8-11)17-14(16,18-13)12-9-5-2-6-10-12/h1-10H InChIKey = GKYFQRQKPYPLGJ-UHFFFAOYSA-N (reagent for the respective preparation of selenoamides2, 3 and selenocarboxylates4 from amides and carboxylic acids) Alternate Name: Woollins's reagent.
Etzer Darout, Spencer Knapp
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Diphenyl diselenide and diphenyl ditelluride: neurotoxic effect in brain of young rats, in vitro

Molecular and Cellular Biochemistry, 2010
This study examined whether maturity of rat brain may be relevant for the sensitivity to diphenyl diselenide (PhSe)(2) and diphenyl ditelluride (PhTe)(2) on [(3)H]glutamate uptake and release, in vitro. Brain synaptosomes were isolated from young (14- and 30-day-old) and adult rats and incubated at different concentrations of (PhSe)(2) or (PhTe)(2 ...
Ana Cristina Guerra, Souza, Eluza Curte, Stangherlin, Ana Paula, Ardais, Cristina Wayne, Nogueira   +3 more
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Spinal mechanisms of antinociceptive action caused by diphenyl diselenide

Brain Research, 2007
The present study was designed to investigate further the mechanisms involved in the antinociception caused by diphenyl diselenide in behavioral model of pain in mice. Diphenyl diselenide (1-100 mg/kg), given orally, produced significant inhibition of the biting behavior induced by intrathecal (i.t.) injection of glutamate (175 nmol/site) and N-methyl ...
Lucielli, Savegnago, Larissa G, Pinto, Cristiano R, Jesse, João B T, Rocha, Cristina W, Nogueira, Gilson, Zeni   +5 more
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Acute exposure of rabbits to diphenyl diselenide: a toxicological evaluation

Journal of Applied Toxicology, 2010
AbstractThe simple organoselenium compound diphenyl diselenide (PhSe)2 is a promising new pharmacological agent. However, few toxicological evaluations of this molecule have been reported. We evaluated the effects of acute administration of (PhSe)2 on toxicological parameters in rabbits.
Marcos Raniel, Straliotto, Gianni, Mancini, Jade, de Oliveira, Evelise Maria, Nazari, Yara Maria Rauh, Müller, Alcir, Dafre, Susana, Ortiz, Edson Luiz, Silva, Marcelo, Farina, Alexandra, Latini, João Batista Teixeira, Rocha, Andreza Fabro, de Bem   +11 more
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Eco‐Friendly Olefin Dihydroxylation Catalyzed by Diphenyl Diselenide

Advanced Synthesis & Catalysis, 2008
AbstractThe first general and efficient diphenyl diselenide‐catalyzed dihydroxylation of double bonds is presented. Hydrogen peroxide can be used as the oxidizing agent, affording generally good yields and high diasteroselectivity.
SANTORO, STEFANO, SANTI, Claudio, M. SABATINI, TESTAFERRI, Lorenzo, TIECCO, Marcello   +4 more
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Diphenyl diselenide and diphenyl ditelluride affect the rat glutamatergic system in vitro and in vivo

Brain Research, 2001
The aim of this study was to investigate the possible involvement of the glutamatergic system in the toxicity of organochalcogens, since this is an important neurotransmitter system for signal transduction and neural function. The results indicated that 100 microM diphenyl diselenide (PhSe)(2) and diphenyl ditelluride (PhTe)(2) inhibit by 50 and 70 ...
C W, Nogueira, L N, Rotta, M L, Perry, D O, Souza, J B, da Rocha   +4 more
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Diphenyl Diselenide-Loaded Nanocapsules: Preparation and Biological Distribution

Applied Biochemistry and Biotechnology, 2013
Over the past years, organoselenium compounds have been aimed as targets of interest in organic synthesis. Diphenyl diselenide [(PhSe)2] is an important example of this class showing several pharmacological properties. However, the poor water-solubility and its low oral bioavailability may be considered an obstruction for the clinical utility of this ...
Camila F A, Giordani, Diego, de Souza, Luciano, Dornelles, Cristina W, Nogueira, Marta P, Alves, Marina, Prigol, Oscar E D, Rodrigues   +6 more
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Dietary diphenyl diselenide reduces the STZ-induced toxicity

Food and Chemical Toxicology, 2008
Oxidative stress is implicated in the pathogenesis of diabetes mellitus. Selenium supplementation has some benefits in experimental models of diabetes mellitus. This study evaluated whether dietary diphenyl diselenide, a simple synthetic organoselenium compound with antioxidant properties, reduces the streptozotocin (STZ)-induced toxicity.
N B V, Barbosa, J B T, Rocha, J C M, Soares, D C, Wondracek, J F, Gonçalves, M R C, Schetinger, C W, Nogueira   +6 more
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Effects of diphenyl diselenide diet on a model of mercury poisoning

Molecular Biology Reports, 2018
This work investigated the preventive effect of diphenyl diselenide [(PhSe)2] against the toxic effects of mercury in silver catfish (Rhamdia quelen). The animals were treated during 30 consecutive days with a (PhSe)2 supplemented feed (3.0 mg kg-1) or commercial feed. During the last 5 days the animals received a daily intraperitoneal dose of HgCl2 (1.
Tiago da Luz Fiuza, Jossiele Leitemperger, Eduardo Stringini Severo, Aline Teixeira Marins, Aline Blank do Amaral, Maria Ester Pereira, Vania Lucia Loro   +6 more
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Reactions of some main group metals with diphenyl disulphide and diphenyl diselenide

Journal of the Chemical Society, Dalton Transactions, 1988
Indium reacts with both Ph2S2 and Ph2Se2 in refluxing toluene to give the compounds In(EPh)3(E = S or Se) in high yield. Under similar conditions tin gives Sn(EPh)4. Thallium reacts with Ph2Se2 to form TI(SePh), but does not react with Ph2S2. Neither zinc nor gallium reacts with Ph2S2 or Ph2Se2.
Rajesh Kumar, Hassan E. Mabrouk, Dennis G. Tuck   +2 more
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