Results 151 to 160 of about 1,907 (195)

Acute exposure of rabbits to diphenyl diselenide: a toxicological evaluation

Journal of Applied Toxicology, 2010
AbstractThe simple organoselenium compound diphenyl diselenide (PhSe)2 is a promising new pharmacological agent. However, few toxicological evaluations of this molecule have been reported. We evaluated the effects of acute administration of (PhSe)2 on toxicological parameters in rabbits.
Marcos Raniel, Straliotto, Gianni, Mancini, Jade, de Oliveira, Evelise Maria, Nazari, Yara Maria Rauh, Müller, Alcir, Dafre, Susana, Ortiz, Edson Luiz, Silva, Marcelo, Farina, Alexandra, Latini, João Batista Teixeira, Rocha, Andreza Fabro, de Bem   +11 more
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Eco‐Friendly Olefin Dihydroxylation Catalyzed by Diphenyl Diselenide

Advanced Synthesis & Catalysis, 2008
AbstractThe first general and efficient diphenyl diselenide‐catalyzed dihydroxylation of double bonds is presented. Hydrogen peroxide can be used as the oxidizing agent, affording generally good yields and high diasteroselectivity.
SANTORO, STEFANO, SANTI, Claudio, M. SABATINI, TESTAFERRI, Lorenzo, TIECCO, Marcello   +4 more
openaire   +1 more source

Dietary diphenyl diselenide reduces the STZ-induced toxicity

Food and Chemical Toxicology, 2008
Oxidative stress is implicated in the pathogenesis of diabetes mellitus. Selenium supplementation has some benefits in experimental models of diabetes mellitus. This study evaluated whether dietary diphenyl diselenide, a simple synthetic organoselenium compound with antioxidant properties, reduces the streptozotocin (STZ)-induced toxicity.
N B V, Barbosa, J B T, Rocha, J C M, Soares, D C, Wondracek, J F, Gonçalves, M R C, Schetinger, C W, Nogueira   +6 more
openaire   +2 more sources

Effects of diphenyl diselenide diet on a model of mercury poisoning

Molecular Biology Reports, 2018
This work investigated the preventive effect of diphenyl diselenide [(PhSe)2] against the toxic effects of mercury in silver catfish (Rhamdia quelen). The animals were treated during 30 consecutive days with a (PhSe)2 supplemented feed (3.0 mg kg-1) or commercial feed. During the last 5 days the animals received a daily intraperitoneal dose of HgCl2 (1.
Tiago da Luz Fiuza, Jossiele Leitemperger, Eduardo Stringini Severo, Aline Teixeira Marins, Aline Blank do Amaral, Maria Ester Pereira, Vania Lucia Loro   +6 more
openaire   +2 more sources

Reactions of some main group metals with diphenyl disulphide and diphenyl diselenide

Journal of the Chemical Society, Dalton Transactions, 1988
Indium reacts with both Ph2S2 and Ph2Se2 in refluxing toluene to give the compounds In(EPh)3(E = S or Se) in high yield. Under similar conditions tin gives Sn(EPh)4. Thallium reacts with Ph2Se2 to form TI(SePh), but does not react with Ph2S2. Neither zinc nor gallium reacts with Ph2S2 or Ph2Se2.
Rajesh Kumar, Hassan E. Mabrouk, Dennis G. Tuck   +2 more
openaire   +1 more source

Diphenyl Diselenide-Assisted α-Phenylthiolation of Carbonyl Compounds with Diphenyl Disulfide

Bulletin of the Chemical Society of Japan, 2011
Abstract For the cesium carbonate-catalyzed α-phenylthiolation of carbonyl compounds with diphenyl disulfide, the yields of the α-phenylthio carbonyl compounds were dramatically improved by the addition of a catalytic amount of diphenyl diselenide.
Hiroaki Anbou, Rui Umeda, Yutaka Nishiyama   +2 more
openaire   +1 more source

Photo-initiated addition of diphenyl diselenide to allenes

Tetrahedron Letters, 1990
Abstract Free-radical addition of diphenyl diselenide 2 to allenes 1 took place under irradiation through Pyrex with tungusten lamp to provide 1-(phenylselenomethyl)vinyl selenides 3 in excellent yields.
Akiya Ogawa, Kazuyuki Yokoyama, Hiroshi Yokoyama, Masahito Sekiguchi, Nobuaki Kambe, Noboru Sonoda   +5 more
openaire   +1 more source

Molecular Effects of Diphenyl Diselenide on Cholesterol and Glucose Cell Metabolism

Current Medicinal Chemistry, 2013
This study was designed to investigate the molecular effects of diphenyl diselenide ((PhSe)₂) on cholesterol metabolism in HepG2 cell line in a dose-dependent manner. The protein levels of both total and phosphorylated 3- hydroxy-3-methylglutaryl coenzyme A reductase (HMGR and P-HMGR), low-density lipoprotein receptors (LDLr) and the proteins involved ...
da Rocha, J. T, Trapani, L, SEGATTO, MARCO, La Rosa, P, Nogueira, C. W, Zeni, G, Pallottini, V.   +6 more
openaire   +5 more sources

Odorless Diphenyl Diselenide and Disulfide: Syntheses and Applications

Synthesis, 2005
Bis[4-(trimethylsilyl)phenyl]diselenide (3) and bis[4-(trimethylsilyl)phenyl]disulfide (31) are found to be odorless equivalents of the commonly used diphenyl diselenide and diphenyl disulfide, respectively. The diselenide 3 is shown to be useful in the preparation of odorless selenium(II) chloride 26 and selenium(IV) trichloride 28 that follow similar
Manabu Node, Pranab K. Patra, Kandasamy Shanmugasundaram, Manabu Matoba, Kiyoharu Nishide, Tetsuya Kajimoto   +5 more
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Potential renal and hepatic toxicity of diphenyl diselenide, diphenyl ditelluride and Ebselen for rats and mice

Toxicology Letters, 2003
The occupational importance of tellurium and selenium is growing rapidly, but the biochemistry of exposure is poorly understood. Here we report the potential toxic effects of diphenyl diselenide (PhSe)(2), diphenyl ditelluride (PhTe)(2) and Ebselen in rats and mice. The results suggest that (PhTe)(2) is more toxic in rats than mice. (PhSe)(2), (PhTe)(2)
F C, Meotti, V C, Borges, G, Zeni, J B T, Rocha, C W, Nogueira   +4 more
openaire   +2 more sources