Results 181 to 190 of about 31,873 (244)

Small Proteoglycans, Big Impact: Decorin, Biglycan, and Asporin in Musculoskeletal Tissue Health and Disease

open access: yesProteoglycan Research, Volume 4, Issue 4, October 2026.
ABSTRACT The extracellular matrix (ECM) is a dynamic and information‐rich network that integrates structural support with biochemical and mechanical signaling. Among its key regulatory components are the Small Leucine‐Rich Proteoglycans (SLRPs), a family of matrix molecules that coordinate extracellular architecture with cell signaling.
Alessandra Leone   +2 more
wiley   +1 more source

Honeydew microbial ecology: a neglected frontier in multitrophic networks. [PDF]

open access: yesFEMS Microbiol Ecol
van Neerbos FAC   +3 more
europepmc   +1 more source

Hyaluronan in Ocular Surface Health and Disease: From Biological Mechanisms to Therapeutic Applications

open access: yesProteoglycan Research, Volume 4, Issue 4, October 2026.
ABSTRACT Hyaluronan (HA) is an ubiquitous non‐sulfated glycosaminoglycan with unique physicochemical and biological properties that underpin its essential roles in tissue homeostasis, repair, and diseases. First identified in the vitreous humor of the eye, HA has a long‐standing history in ophthalmology as a key component of ophthalmic visco‐surgical ...
Sudhir Verma   +3 more
wiley   +1 more source

Proteoglycans and Lyme Disease: Molecular Interfaces in Adhesion, Tissue Tropism, and Therapeutic Discovery

open access: yesProteoglycan Research, Volume 4, Issue 4, October 2026.
ABSTRACT Lyme disease, caused by spirochetes of the Borrelia burgdorferi sensu lato complex, is a multisystem tick‐borne infection in which bacterial dissemination depends on interactions with host cells and the extracellular matrix (ECM). Proteoglycans (PGs), composed of core proteins modified with glycosaminoglycan (GAG) chains, are abundant and ...
Fuming Zhang, Ke Xia, Yi‐Pin Lin
wiley   +1 more source

Hevea brasiliensis seeds: A novel sustainable feedstock for ethanol production

open access: yesVietnam Journal of Chemistry, Volume 64, Issue 5, Page 682-695, October 2026.
Abstract The rubber tree (Hevea brasiliensis) is cultivated on a large scale mainly for the extraction of latex in Brazil and Southeast Asia, also generating large quantities of seeds. These seeds currently do not have large‐scale applications and may thus be considered as a residue.
Giovano Tochetto   +4 more
wiley   +1 more source

Novel Flavonoid Senotherapeutics Identified by Phenotypic Drug Discovery Reduce Senescence and Improve Multiple Markers of Healthspan

open access: yesAging Cell, Volume 25, Issue 10, October 2026.
Phenotypic screening and SAR‐guided drug design identified two flavonoid‐derived senolytics, SR29384 and SR31133, which selectively killed different types of senescent cells more efficiently and with greater selectivity than fisetin in culture. In aged and progeroid mice, these fisetin analogs reduced tissue senescence and improved physical function ...
Lei Justan Zhang   +17 more
wiley   +1 more source

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