Results 11 to 20 of about 193,025 (292)

Bioinspired NEMS-Prospective of Collaboration with Nature [PDF]

, 2022
The fields of micro- and nanomechanics are strongly interconnected with the development of micro-electro-mechanical (MEMS) and nano-electro-mechanical (NEMS) devices, their fabrication and applications.
Bokić, Bojana, Kolarić, Branko, Simović-Pavlović, Marina, Vasiljević, Darko   +3 more
core   +4 more sources

Induced pluripotent stem cell-based organ-on-a-chip as personalized drug screening tools: A focus on neurodegenerative disorders [PDF]

, 2022
The Organ-on-a-Chip (OoC) technology shows great potential to revolutionize the drugs development pipeline by mimicking the physiological environment and functions of human organs.
Albani, Diego, Campanile, Marzia, Fanizza, Francesca, Forloni, Gianluigi, Giordano, Carmen   +4 more
core   +4 more sources

Microfluidic Platforms to Unravel Mysteries of Alzheimer's Disease: How Far Have We Come? [PDF]

, 2021
Alzheimer’s disease (AD) is a significant health concern with enormous social and economic impact globally. The gradual deterioration of cognitive functions and irreversible neuronal losses are primary features of the disease.
Chandra Goud, Macherla Sharath, Gupta, Piyush Kumar, Hawthorne, Susan, Jha, Niraj Kumar, Jha, Saurabh Kumar, Mandal, Debabrata, Ojha, Shreesh, Prasanna, Pragya, Rahul, Vedanabhatla, Rathee, Shweta, Sharma, Ankur, Villa, Chiara, Yadav, Pardeep   +12 more
core   +3 more sources

Human vascularized bile duct-on-a chip: a multi-cellular micro-physiological system for studying cholestatic liver disease

Biofabrication, 2023
Exploring the pathogenesis of and developing therapies for cholestatic liver diseases such as primary sclerosing cholangitis (PSC) remains challenging, partly due to a paucity of in vitro models that capture the complex environments contributing to ...
Yu Du, I. D. de Jong, Kapish Gupta, O. Waisbourd-Zinman, Adi Har-Zahav, C. Soroka, James L Boyer, J. Llewellyn, Chengyang Liu, A. Naji, William Polacheck, Rebecca G. Wells   +11 more
semanticscholar   +1 more source

Towards establishing human body-on-a-chip systems

Stem Cell Research & Therapy, 2022
Body-on-a-chip (BoC) platforms are established from multiple organs-on-chips (OoCs) to recapitulate the interactions between different tissues. Recently, Vunjak-Novakovic and colleagues reported the creation of a BoC system comprising four fluidically ...
Zhong Alan Li, Rocky S. Tuan
doaj   +1 more source

Alveolus Lung-on-a-Chip Platform: A Proposal

Chemosensors, 2021
Respiratory diseases are top-ranked causes of deaths and disabilities around the world, making new approaches to the treatment necessary. In recent years, lung-on-a-chip platforms have emerged as a potential candidate to replace animal experiments ...
Noelia Campillo, Vinicius Rosa Oliveira, Renata Kelly da Palma   +2 more
doaj   +1 more source

Cytokine induced inflammatory bowel disease model using organ-on-a-chip technology

PLoS ONE, 2023
Over 2 million people in North America suffer from inflammatory bowel disease (IBD), a chronic and idiopathic inflammatory condition. While previous research has primarily focused on studying immune cells as a cause and therapeutic target for IBD, recent
Christine A. Tataru, Maya Livni, Carrie L. Marean-Reardon, Maria Clara Franco, M. David   +4 more
semanticscholar   +1 more source

Aorta smooth muscle-on-a-chip reveals impaired mitochondrial dynamics as a therapeutic target for aortic aneurysm in bicuspid aortic valve disease

eLife, 2021
Background: Bicuspid aortic valve (BAV) is the most common congenital cardiovascular disease in general population and is frequently associated with the development of thoracic aortic aneurysm (TAA).
A. Mieradilijiang, Shichao Zhu, Shiqiang Yan, Kehua Xu, Jingjing Zhang, S. Luo, Wenrui Ma, Md. Fazle Alam, Yuyi Tang, Hui Huang, Nan Chen, Li Wang, Guoquan Yan, Jun Li, H. Lai, Chunsheng Wang, K. Zhu, Weijia Zhang   +17 more
semanticscholar   +1 more source

Entwicklung und Automatisierung 3D-gedruckter mikrofluidischer Systeme zur Integration und Kultivierung adhärenter Zellkulturen [PDF]

, 2022
Mikrofluidische Systeme werden zur Manipulation von Flüssigkeiten auf Mikroebene eingesetzt. Von ihnen profitieren insbesondere Biowissenschaften durch die Reduktion von Reagenzien und die Automatisierung ganzer Arbeitsabläufe.
Winkler, Steffen Nils
core   +1 more source

Hyperglycemic Neurovasculature‐On‐A‐Chip to Study the Effect of SIRT1‐Targeted Therapy for the Type 3 Diabetes “Alzheimer's Disease”

Advanced Science, 2022
Diabetes mellitus (DM) is closely related to Alzheimer's disease (AD), but individual cellular changes and the possibilities of recovery through molecular level regulation have not been investigated.
Minjeong Jang, Nakwon Choi, Hong Nam Kim
doaj   +1 more source