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Biomarkers for neurodegenerative diseases
Current Opinion in Neurology, 2005A major goal of current clinical research in neurodegenerative diseases is to improve early detection of disease and presymptomatic detection of neuronal dysfunction. We also need better tools to assess disease progression in this group of disorders.
Susie M D, Henley +2 more
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Biomarkers in Parkinson’s Disease
Neurologic ClinicsParkinson's disease (PD) is a leading cause of disability worldwide, and there is a pressing need to develop therapeutics to slow or halt disease progression. The identification of reliable biomarkers of PD at all stages of disease will be a critical step toward optimizing diagnosis and therapeutic development.
Sarah M, Brooker +1 more
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Oxysterols as a biomarker in diseases
Clinica Chimica Acta, 2019Cholesterol is one of the most important chemical substances as a structural element in human cells, and it is very susceptible to oxidation reactions that form oxysterol. Oxysterols exhibit almost the exact structure as cholesterol and a cholesterol precursor (7-dehydrocholesterol) with an additional hydroxyl, epoxy or ketone moiety.
Adam Zmysłowski, Arkadiusz Szterk
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Expert Review of Molecular Diagnostics, 2004
The challenge of medical practice today is to identify individuals who are at risk of developing disease, determine the severity of the disease and distinguish the responders from the nonresponders to therapy (individualized medicine). Advances in molecular genetics and biology have shifted the paradigm for identification of markers from large-scale ...
A J, Marian, Vijay, Nambi
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The challenge of medical practice today is to identify individuals who are at risk of developing disease, determine the severity of the disease and distinguish the responders from the nonresponders to therapy (individualized medicine). Advances in molecular genetics and biology have shifted the paradigm for identification of markers from large-scale ...
A J, Marian, Vijay, Nambi
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Biomarkers in Alzheimer’s Disease
Neurobiology of Aging, 1998BIOMARKERS are useful in mapping disease pathogenesis from several perspectives. Identification of risk factors can lead to prediction and, in some instances, a quantifiable trait to follow for therapy and to utilize in the search for genetic factors that enhance risk. Biomarkers can also be useful in the diagnosis of a disease.
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Biomarkers for Parkinson's disease
Experimental Neurology, 2009With the advent of systems biological concepts there has been a surge of interest in biological factors, or biomarkers that can be measured and which allow the identification of individuals at risk. Biomarkers for Parkinson's disease have been identified which provide evidence of systemic metabolic dysregulation in this disorder. Such biomarkers can be
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Clinical Gastroenterology and Hepatology, 2017
Bor, Serhat, Ergun, Pelin, Kipcak, Sezgi
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Bor, Serhat, Ergun, Pelin, Kipcak, Sezgi
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Machine Learning in Epigenetic Diseases
Medical Epigenetics, 2021Robert E Akins, Karyn Robinson
exaly