Results 21 to 30 of about 744,500 (48)

Cytokines and chemokines as regulators of skeletal muscle inflammation: presenting the case of Duchenne muscular dystrophy [PDF]

, 2013
Duchenne muscular dystrophy is a severe inherited muscle disease that affects 1 in 3500 boys worldwide. Infiltration of skeletal muscle by inflammatory cells is an important facet of disease pathophysiology and is strongly associated with disease ...
De Bleecker, Jan, De Paepe, Boel
core   +3 more sources

Burkholderia pseudomallei: animal models of infection.

, 2008
A range of animal models of Burkholderia pseudomallei infection have been reported, and the host species differ widely both in their susceptibility to infection and in the pathogenesis of disease.
Atkins, Tim, Bancroft, Gregory J, Cuccui, Jon, Easton, Anna, Haque, Ashraful, Harley, Vicki, Russell, Paul, Sarkar-Tyson, Mitali, Titball, Richard W, Wren, Brendan   +9 more
core   +1 more source

Animal models of ulcerative colitis and their application in drug research [PDF]

, 2014
The specific pathogenesis underlying inflammatory bowel disease is complex, and it is even more difficult to decipher the pathophysiology to explain for the similarities and differences between two of its major subtypes, Crohn’s disease and ulcerative ...
Low, Daren, Mizoguchi, Emiko, Nguyen, Deanna D   +2 more
core   +1 more source

Large animal models of cardiovascular disease [PDF]

, 2016
The human cardiovascular system is a complex arrangement of specialized structures with distinct functions. The molecular landscape, including the genome, transcriptome and proteome, is pivotal to the biological complexity of both normal and abnormal ...
Abedin, Agarwala, Aikawa, Akahori, Al-Mashhadi, Albright, Ali, Anderson, Arroyo, Atkinson, Avila-Díaz, Bach, Back, Balaoing, Barter, Bellinger, Bendixen, Berliner, Besser, Bluestein, Boström, Boyce, Breslow, Bucay, Bunton, Butcher, Butcher, Butcher, Butcher, Caira, Calkin, Carlson, Casani, Cerne, Chan, Chen, Chen, Cheng, Cheng, Chorro, Cimini, Civeira, Collins, Cowell, Cowell, Cranley, Crowle, Cuniberti, Dahlem, Daida, Davies, Davignon, Davis, Demer, Dhore, Dixon, Dixon, Dixon, Doeing, Dumonde, Dyson, Ebrahim, Edwards, Edwards, Fenning, Feussner, Fischer, Fitzpatrick, Freeman, Freeman, Frink, Frydman, Gal, Gal, Garg, Gehron Robey, Gerrity, Getz, Giachelli, Giachelli, Giachelli, Go, Goldberg, Gotoh, Groenink, Gruen, Grunwald, Guerraty, Gupta, Gupta, Haffner, Hai, Hall, Hart, Hasler-Rapacz, Hasty, Hasty, Hayashi, Hines, Hirano, Hirota, Hobbs, Hsu, Huang, Huesa, Imaizumi, Iung, Ix, Jiang, Johnson, Johnson, Johnson, Kaniewska, Kannel, Kapourchali, Karsenty, Katsumata, Kenealy, Kennedy, Khan, Kim, Kim, King, Klocke, Koleganova, Koos, Koskinas, Kreutzenberg, Kumar, Kunjathoor, Lacroix, Laforest, Larson, Leopold, Levy-Litan, Li, Lillico, Lloyd, London, Lopez, Lorenz-Depiereux, Lowe, Lozano, Lunney, Luo, Mackenzie, Mackenzie, Maganti, Mahley, Manduteanu, Mansford, Martin, Mazzone, McKellar, McNally, Meer, Mertens, Messier, Meurens, Milewicz, Miller, Mizobuchi, Mizobuchi, Moghadasian, Moghadasian, Moghadasian, Mohamed, Mohler, Mohler, Munford, Nakamura, Nataatmadja, Neeb, Ni, Nigam, Nitschke, Nordon, O'Brien, Oliveira, Olsson, Ortlepp, Otero, Otero, Otis, Otto, Otto, Paranya, Parhami, Park, Pereira, Phillips, Potter, Potter, Powell-Braxton, Prescott, Prescott, Price, Quondamatteo, Rader, Raffai, Rajamannan, Rajamannan, Ramirez, Reaven, Reggio, Reiser, Rerup, Rettenberger, Rezg, Riches, Roberts, Rosengren, Ross, Ross, Rossebø, Rubin, Russell, Rutsch, Rutsch, Rutsch, Sakai, Sanan, Sancho, Sanjana, Schinke, Schoen, Schwartz, Schwartz, Schäfer, Shanahan, Shimizu, Shroff, Sider, Sider, Simmons, Simmons, Singleton, Siu, Skold, Skold, Solomon, Speer, Speer, Steitz, Stout, Sturek, Sturek, Sturek, Sugitani, Suzuki, Szkudelski, Tanimura, Tenger, Tesson, Towler, Townsend, Trollope, Tse, Turk, Turk, Urnov, Vengrenyuk, Vercauteren, Verreth, Verreth, Viaene, Vilahur, Vodicka, Wachi, Wada, Walters, Warnock, Warren, Wendt, Wenk, White, White, White, WHO, Wiggers, Wouters, Wu, Yang, Yao, Yokozawa, Yperman, Yu, Zadelaar, Zaragoza, Zhu, Zhu, Zuccollo   +291 more
core   +1 more source

Vaccination is a suitable tool in the control of Aujeszky's disease outbreaks in pigs using a Population Dynamics P systems model [PDF]

, 2020
Aujeszky's disease is one of the main pig viral diseases and results in considerable economic losses in the pork production industry. The disease can be controlled using preventive measures such as improved stock management and vaccination throughout the
Colomer, M. Àngels (Maria Àngels), Fraile Sauce, Lorenzo José, Margalida, Antoni   +2 more
core   +3 more sources

Animal models of urinary stone disease [PDF]

, 2016
The etiology of stone disease remains unknown despite the major technological advances in the treatment of urinary calculi. Clinically, urologists have relied on 24-h urine collections for the last 30-40 years to help direct medical therapy in hopes of ...
Chi, Thomas, Stoller, Marshall L, Taguchi, Kazumi, Tzou, David T   +3 more
core   +2 more sources

Dual mTOR/PI3K inhibition limits PI3K-dependent pathways activated upon mTOR inhibition in autosomal dominant polycystic kidney disease [PDF]

, 2018
Autosomal dominant polycystic kidney disease (ADPKD) is characterized by the development of kidney cysts leading to kidney failure in adulthood. Inhibition of mammalian target of rapamycin (mTOR) slows polycystic kidney disease (PKD) progression in ...
Arcaro, Alexandre, Castelletti, Deborah, Fu, Xuebin, Liu, Yang, Mischak, Harald, Mullen, William, Pejchinovski, Martin, Serra, Andreas L., Siwy, Justyna, Wang, Xueqi, Watnick, Terry J.   +10 more
core   +2 more sources

Quality of Reporting and Adherence to ARRIVE Guidelines in Animal Studies for Chagas Disease Preclinical Drug Research: A Systematic Review [PDF]

, 2015
Publication of accurate and detailed descriptions of methods in research articles involving animals is essential for health scientists to accurately interpret published data, evaluate results and replicate findings. Inadequate reporting of key aspects of
García Bournissen, Facundo, Gulin, Julián Ernesto Nicolás, Rocco, Daniela Marisa   +2 more
core   +4 more sources

What makes or breaks a campaign to stop an invading plant pathogen? [PDF]

, 2020
Diseases in humans, animals and plants remain an important challenge in our society. Effective control of invasive pathogens often requires coordinated concerted action of a large group of stakeholders.
Alonso Chavez, V, Gottwald, T, Milne, AE, Parnell, SR, van den Bosch, F   +4 more
core   +3 more sources

Gene therapy for allergic diseases [PDF]

, 2011
Airway diseases such as allergic asthma and rhinitis are characterized by a T-helper type 2 (Th2) response. Treatment of allergic airway diseases is currently limited to drugs that relieve disease symptoms and inflammation.
Joos, Guy, Maes, Tania, Tournoy, Kurt
core   +2 more sources