Results 31 to 40 of about 1,056,424 (268)
Centipede Venoms and Their Components: Resources for Potential Therapeutic Applications
Toxins, 2015 Venomous animals have evolved with sophisticated bio-chemical strategies to arrest prey and defend themselves from natural predators. In recent years, peptide toxins from venomous animals have drawn considerable attention from researchers due to their ...
Md Abdul Hakim, Shilong Yang, Ren Lai
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Animal models of neurodegenerative diseases [PDF]
Nature Neuroscience, 2018 Animal models of adult-onset neurodegenerative diseases have enhanced the understanding of the molecular pathogenesis of Alzheimer's disease, Parkinson's disease, frontotemporal dementia, and amyotrophic lateral sclerosis. Nevertheless, our understanding of these disorders and the development of mechanistically designed therapeutics can still benefit ...
Ted M. Dawson +2 more
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Signal Transduction and Targeted Therapy, 2021 Influenza A virus may circulate simultaneously with the SARS-CoV-2 virus, leading to more serious respiratory diseases during this winter. However, the influence of these viruses on disease outcome when both influenza A and SARS-CoV-2 are present in the ...
Linlin Bao +19 more
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Animal Models in Behçet's Disease [PDF]
Pathology Research International, 2012 Behçet's disease is a chronic, recurrent, multisystemic, inflammatory disorder affecting mainly the oral and urogenital mucosa and the uveal tract. Although the etiology and pathogenesis of Behçet's disease are unknown, numerous etiologies have been proposed, including environmental, infectious, and immunological factors; an autoimmune basis ...
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Animal models of psychiatric disease
Current Opinion in Genetics & Development, 2008 Animal models of psychiatric diseases are useful tools for screening new drugs and for investigating the mechanisms of those disorders. Despite the difficulties inherent in modelling human psychiatric phenotypes in animals, there has been recent success identifying mutations in mice that give rise to some of the characteristic features of anxiety ...
Flint, J, Shifman, S
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Animal Models for Neural Diseases [PDF]
Toxicologic Pathology, 2010 “Animal Models of Neural Disease” was the focus of General Session 5 at a 2010 scientific symposium that was sponsored jointly by the Society of Toxicologic Pathology (STP) and the International Federation of Societies of Toxicologic Pathologists (IFSTP).
Ronald B. DeMattos +5 more
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Bidirectional genetic overlap between bipolar disorder and intelligence
BMC Medicine, 2022 Background Bipolar disorder (BD) is a highly heritable psychiatric illness exhibiting substantial correlation with intelligence. Methods To investigate the shared genetic signatures between BD and intelligence, we utilized the summary statistics from ...
Meng-Yuan Shang +8 more
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Molecular Cancer, 2021 Background Non-small cell lung cancer (NSCLC) is the most common type of human lung cancers, which has diverse pathological features. Although many signaling pathways and therapeutic targets have been defined to play important roles in NSCLC, limiting ...
Yaomei He +10 more
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Moving in the Dark: Enlightening the Spatial Population Ecology of European Cave Salamanders
Population Ecology, EarlyView.We assessed individual interactions, movement ecology and activity patterns of a subterranean population of Speleomantes strinatii, applying spatial capture–recapture modeling to a photographic dataset of 104 individuals. ABSTRACT Space use and movement are fundamental aspects of organisms' ecology, mirroring individual fitness, behavior, and life ...
Giacomo Rosa +2 more
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Object-translocation induces event coding in the rat hippocampus
Communications BiologyEpisodic memory is the ability to recall personally experienced events that are situated within specific spatial contexts. Within a navigation environment, salient objects can function as landmarks, and interactions with them can be encoded as distinct ...
Ya-Li Duan +9 more
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