Results 31 to 40 of about 1,810,523 (315)
Cohesin promotes HSV-1 lytic transcription by facilitating the binding of RNA Pol II on viral genes
Virology Journal, 2021 Background Herpes Simplex Virus type I (HSV-1) is a large double-stranded DNA virus that enters productive infection in epithelial cells and reorganizes the host nucleus.
Xin Li +10 more
doaj +1 more source
Primary skin fibroblasts as a model of Parkinson's disease [PDF]
, 2012 Parkinson's disease is the second most frequent neurodegenerative disorder. While most cases occur sporadic mutations in a growing number of genes including Parkin (PARK2) and PINK1 (PARK6) have been associated with the disease.
A Grunewald +84 more
core +1 more source
Vaccination is a suitable tool in the control of Aujeszky's disease outbreaks in pigs using a Population Dynamics P systems model [PDF]
, 2020 Aujeszky's disease is one of the main pig viral diseases and results in considerable economic losses in the pork production industry. The disease can be controlled using preventive measures such as improved stock management and vaccination throughout the
Colomer, M. Àngels (Maria Àngels) +2 more
core +3 more sources
BMC Medicine, 2023 Background Schizophrenia and bipolar disorder (BD) are believed to share clinical symptoms, genetic risk, etiological factors, and pathogenic mechanisms.
Zhi-Hui Yang +13 more
doaj +1 more source
Isolation of Joint-infiltrating Cells
Bio-Protocol, 2016 Infiltration of leukocytes into joints is one of the main features of autoimmune inflammatory arthritis. Here, we describe the protocol for isolation of joint-infiltrating cells in mice.
Aoi Akitsu, Yoichiro Iwakura
doaj +1 more source
Serotonin system implication in L-DOPA-induced dyskinesia: from animal models to clinical investigations [PDF]
, 2014 In the recent years, the serotonin system has emerged as a key player in the induction of l-DOPA-induced dyskinesia (LID) in animal models of Parkinson's disease. In fact, serotonin neurons possess the enzymatic machinery able to convert exogenous l-DOPA
CARTA, MANOLO, TRONCI, ELISABETTA
core +1 more source
Scientific Reports, 2017 The elderly population infected with HIV-1 is often characterized by the rapid AIDS progression and poor treatment outcome, possibly because of immunosenescence resulting from both HIV infection and aging.
Hong-Yi Zheng +11 more
doaj +1 more source
Cytokines and chemokines as regulators of skeletal muscle inflammation: presenting the case of Duchenne muscular dystrophy [PDF]
, 2013 Duchenne muscular dystrophy is a severe inherited muscle disease that affects 1 in 3500 boys worldwide. Infiltration of skeletal muscle by inflammatory cells is an important facet of disease pathophysiology and is strongly associated with disease ...
De Bleecker, Jan, De Paepe, Boel
core +3 more sources
Animal models in neurodegenerative diseases [PDF]
, 2007 Ideally, animal models of neurodegenerative diseases should reproduce the clinical manifestation of the disease and a selective neuronal loss. In this review we will take as an example Parkinson's disease because its pathophysiology is well known and the neuronal loss well characterized.
openaire +4 more sources
Circadian Disruption and Metabolic Disease: Findings from Animal Models [PDF]
, 2010 Social opportunities and work demands have caused humans to become increasingly active during the late evening hours, leading to a shift from the predominantly diurnal lifestyle of our ancestors to a more nocturnal one.
Arble, Deanna M. +3 more
core +2 more sources