Results 31 to 40 of about 1,875,199 (316)
Cohesin promotes HSV-1 lytic transcription by facilitating the binding of RNA Pol II on viral genes
Virology Journal, 2021 Background Herpes Simplex Virus type I (HSV-1) is a large double-stranded DNA virus that enters productive infection in epithelial cells and reorganizes the host nucleus.
Xin Li +10 more
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Improving translational studies: lessons from rare neuromuscular diseases [PDF]
, 2015 Animal models play a key role in the development of novel treatments for human disease. This is particularly true for rare diseases – defined as disorders that affect less than 1 in 2000 people in the human population – for which, very often, there are ...
Wells, D J
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Isolation of Joint-infiltrating Cells
Bio-Protocol, 2016 Infiltration of leukocytes into joints is one of the main features of autoimmune inflammatory arthritis. Here, we describe the protocol for isolation of joint-infiltrating cells in mice.
Aoi Akitsu, Yoichiro Iwakura
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Primary skin fibroblasts as a model of Parkinson's disease [PDF]
, 2012 Parkinson's disease is the second most frequent neurodegenerative disorder. While most cases occur sporadic mutations in a growing number of genes including Parkin (PARK2) and PINK1 (PARK6) have been associated with the disease.
A Grunewald +84 more
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Vaccination is a suitable tool in the control of Aujeszky's disease outbreaks in pigs using a Population Dynamics P systems model [PDF]
, 2020 Aujeszky's disease is one of the main pig viral diseases and results in considerable economic losses in the pork production industry. The disease can be controlled using preventive measures such as improved stock management and vaccination throughout the
Colomer, M. Àngels (Maria Àngels) +2 more
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Animal Models of Huntington's Disease [PDF]
ILAR Journal, 2007 Huntington's disease (HD) is a neurological disorder caused by a genetic mutation in the IT15 gene. Progressive cell death in the striatum and cortex, and accompanying declines in cognitive, motor, and psychiatric functions, are characteristic of the disease.
Shilpa, Ramaswamy +2 more
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Scientific Reports, 2017 The elderly population infected with HIV-1 is often characterized by the rapid AIDS progression and poor treatment outcome, possibly because of immunosenescence resulting from both HIV infection and aging.
Hong-Yi Zheng +11 more
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BMC Medicine, 2023 Background Schizophrenia and bipolar disorder (BD) are believed to share clinical symptoms, genetic risk, etiological factors, and pathogenic mechanisms.
Zhi-Hui Yang +13 more
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Cytokines and chemokines as regulators of skeletal muscle inflammation: presenting the case of Duchenne muscular dystrophy [PDF]
, 2013 Duchenne muscular dystrophy is a severe inherited muscle disease that affects 1 in 3500 boys worldwide. Infiltration of skeletal muscle by inflammatory cells is an important facet of disease pathophysiology and is strongly associated with disease ...
De Bleecker, Jan, De Paepe, Boel
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Centipede Venoms and Their Components: Resources for Potential Therapeutic Applications
Toxins, 2015 Venomous animals have evolved with sophisticated bio-chemical strategies to arrest prey and defend themselves from natural predators. In recent years, peptide toxins from venomous animals have drawn considerable attention from researchers due to their ...
Md Abdul Hakim, Shilong Yang, Ren Lai
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