Inhibition of Neuropathic Pain by a Potent Disintegrin - Triflavin [PDF]
, 2009 Injury to peripheral nerves may result in severe and intractable neuropathic pain. Many efforts have been focused on the elucidation of the mechanisms of neuropathic pain.
符文美;孫維仁;彭惠琴;劉鴻祺;黃德富 +1 more
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Platelet Activation Caused by Disintegrin and a GPIIb/IIIa Monoclonal Antibody AP2 [PDF]
, 2007 蛇毒成分中，有一類含 RGD 序列之低分子量強力血小板凝集抑制劑，稱作抗黏著蛇毒蛋白 (Disintegrin)， Accutin、 Triflavin、 Rhodostomin 皆是屬於 Disintegrin。此類蛋白不僅可抑制 fibrinogen 結合到血小板 integrin αIIbβ3，也能阻斷其他細胞與 RGD 有相關性的黏著分子的結合反應。我們從台灣的百步蛇原毒中精製出 accutin。 Accutin 為一種血小板凝集抑制劑，可依濃度相關性的抑制 collagen 引發的凝集反應 ...
Ho, Pei-Lin, 何佩陵
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A New Short Chain Rgd-Containing Disintegrin, Accutin, Inhibits the Commonpathway of Human Platelet Aggregation [PDF]
, 2008 A new short-chain disintegrin, accutin, was purified from the FormosanAgkistrodon acutus venom by using of gel filtration, ion exchanger andreverse phase HPLC. The homogeneous protein is a 47-residue polypeptide witha molecular mass of 5241 Da containing
葉嘉新;彭惠琴;黃德富 +1 more
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Structural basis for the differential recognition of integrin αvβ3 by rhodostomin and trimucrin. [PDF]
Commun BiolWang YT +5 more
europepmc +1 more source
Purified zymogens reveal mechanisms of snake venom metalloproteinase auto-activation. [PDF]
ElifeHall S +17 more
europepmc +1 more source
ADAM9 in tumor biology: molecular functions, clinical implications, and therapeutic targeting. [PDF]
Cell Mol Biol LettHo KH, Wu CJ, Yang YC, Chien MH.
europepmc +1 more source
A disintegrin and metalloproteinase with thrombospondin motifs 4-targeted molecular magnetic resonance imaging for early detection of extracellular matrix remodeling in a porcine model of abdominal aortic aneurysm. [PDF]
J Cardiovasc Magn ResonRanner-Hafferl MHH +15 more
europepmc +1 more source
Daratumumab for relapsed refractory immune thrombotic thrombocytopenic purpura: initial response and long-term follow-up. [PDF]
Res Pract Thromb HaemostSchimmer R +6 more
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An Integrative Proteotranscriptomics Approach Reveals New ADAM9 Substrates and Downstream Pathways. [PDF]
Mol Cell ProteomicsLu C +7 more
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