Results 81 to 90 of about 78,401 (264)

Confocal laser scanning microscope, raman microscopy and western blotting to evaluate inflammatory response after myocardial infarction [PDF]

open access: yes, 2015
Cardiac muscle necrosis is associated with inflammatory cascade that clears the infarct from dead cells and matrix debris, and then replaces the damaged tissue with scar, through three overlapping phases: the inflammatory phase, the proliferative phase
Cantatore, S   +6 more
core   +1 more source

Uncoupling TGFβ1 signalling from collagen protein synthesis in Dupuytren's disease

open access: yesThe Journal of Pathology, EarlyView.
Abstract Dupuytren's disease is a fibroproliferative disorder of the palmer fascia (PF) characterised by flexion contractures in the hand. Dupuytren's disease can be treated surgically, but disease recurrence rates are high, potentially due to continual production of matrisomal proteins.
Gabriella Cooper   +12 more
wiley   +1 more source

Isolation of bothrasperin, a disintegrin with potent platelet aggregation inhibitory activity, from the venom of the snake Bothrops asper

open access: yesRevista de Biología Tropical, 2003
The venom of Bothrops asper induces severe coagulation disturbances in accidentally envenomed humans. However, only few studies have been conducted to identify components that interact with the hemostatic system in this venom.
Adrián Pinto   +3 more
doaj  

P10.02 EFFECT OF INTEGRIN-EXTRACELLULAR MATRIX INTERACTIONS ON SMALL ARTERY STRUCTURE AND MECHANICS DURING HYPERTENSION AND AGING

open access: yesArtery Research, 2009
An age-related increase in systolic blood pressure and similarities in the consequences of hypertension and aging on arterial structure/mechanics have been reported, particularly in larger arteries.
K.R. Parmar   +2 more
doaj   +1 more source

c-Maf Transcription Factor Regulates ADAMTS-12 Expression in Human Chondrogenic Cells. [PDF]

open access: yes, 2013
ObjectiveADAMTS (a disintegrin and metalloproteinase with thrombospondin type-1 motif) zinc metalloproteinases are important during the synthesis and breakdown of cartilage extracellular matrix.
Amanatullah, Derek F   +4 more
core   +2 more sources

A Disintegrin and Metalloprotease 12 Promotes Tumor Progression by Inhibiting Apoptosis in Human Colorectal Cancer [PDF]

open access: gold, 2021
Young‐Lan Park   +10 more
openalex   +1 more source

An engineered epididymal cell line provides a sustainable source of functional extracellular vesicles for in vitro sperm preservation: A multi‐omics and functional study

open access: yesVIEW, EarlyView.
ABSTRACT This study investigated the function of epididymal extracellular vesicles (EVs) in overcoming sperm post‐testicular modification deficiencies. Although EVs derived from the epididymis play a crucial role in intercellular communication and molecular exchange, there is limited research addressing how EVs released by in vitro cultured epididymal ...
Long Li   +10 more
wiley   +1 more source

Inhibition of adipogenesis by RGD-dependent disintegrin

open access: yesBiochemical Pharmacology, 2005
Adipogenesis plays a central role in obesity development. The processes of adipogenesis include migration, adhesion, proliferation and survival of preadipocytes and differentiation to mature adipocytes. Many of these biological functions are related to integrins.
Lin, Yu-Ting   +5 more
openaire   +2 more sources

Metalloprotease-Disintegrin MDC9: Intracellular Maturation and Catalytic Activity [PDF]

open access: yesJournal of Biological Chemistry, 1999
Metalloprotease disintegrins are a family of membrane-anchored glycoproteins that are known to function in fertilization, myoblast fusion, neurogenesis, and ectodomain shedding of tumor necrosis factor (TNF)-alpha. Here we report the analysis of the intracellular maturation and catalytic activity of the widely expressed metalloprotease disintegrin MDC9.
M, Roghani   +9 more
openaire   +2 more sources

Inflammatory effects of snake venom metalloproteinases

open access: yesMemorias do Instituto Oswaldo Cruz, 2005
Metalloproteinases are abundant enzymes in crotaline and viperine snake venoms. They are relevant in the pathophysiology of envenomation, being responsible for local and systemic hemorrhage frequently observed in the victims.
Catarina de Fátima Pereira Teixeira   +3 more
doaj   +1 more source

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