Results 101 to 110 of about 62,920 (233)

Plasma ADAMTS13 activity in healthy dogs and dogs with chronic enteropathy

Journal of Small Animal Practice, EarlyView.
Objectives A disintegrin and metalloproteinase with thrombospondin type 1 motif, member 13 is a von Willebrand factor cleaving enzyme that is associated with prothrombotic/hypercoagulable states in humans. In people, A disintegrin and metalloproteinase with thrombospondin type 1 motif, member 13 activity is reduced with inflammatory bowel disease ...
S. I. Barth, S. M. DeMonaco, B. J. Conner, P. B. S. Serpa, A. R. Wilkinson   +4 more
wiley   +1 more source

ADAM33: a cellular model of over-expression. From full length to soluble [PDF]

Polymorphic variation in the A Disintegrin And Metalloprotease 33 (ADAM33) genehas been associated with asthma and bronchial hyperresponsiveness. The ADAMfamily of proteins has a multi-domain structure and has diverse biological functionswhich can ...
Harvey, Anna
core  

Immunohistochemical Expression of Invadopodia‐Associated Proteins in Subtypes of Unicystic Ameloblastoma

Oral Diseases, EarlyView.
ABSTRACT Objective This study aims to investigate the expression of invadopodia‐associated proteins—HIF‐1α, NOTCH‐1, ADAM‐12, and HB‐EGF—across different histological subtypes of unicystic ameloblastomas (UA) to assess their invasiveness under hypoxic conditions.
Gabriela Cristina Avertano Rocha da Silveira, Rebeca Vieira Costa, Flavia Letícia Magalhães Lemos, Antonia Taiane Lopes de Moraes, Maria Sueli da Silva Kataoka, Vanessa Morais Freitas, Douglas Magno Guimarães, Ana Paula Neutzling Gomes, Adriana Etges, Fabricio Passador Santos, Vera Cavalcanti de Araújo, Andrew Mark Smith, Sérgio de Melo Alves Júnior, Ruy Gastaldoni Jaeger, João de Jesus Viana Pinheiro   +14 more
wiley   +1 more source

ADAMDEC1 and FGF2/FGFR1 signaling constitute a positive feedback loop to maintain GBM cancer stem cells

Molecular & Cellular Oncology, 2020
Identification of targetable mechanisms that maintain glioblastoma cancer stem cells (CSCs) remain a priority. Our study reveals a new mechanism by which a disintegrin and metalloproteinase domain-like protein decysin 1 promotes CSC maintenance through ...
Ana Jimenez-Pascual, Justin D. Lathia, Florian A. Siebzehnrubl   +2 more
doaj   +1 more source

Cytosolic SH3-interactions of ADAM12-disintegrin-metalloprotease [PDF]

, 2007
Background: ADAM proteins (a disintegrin and metalloprotease) are membrane proteins that consist of several functional domains. ADAM proteins are able to mediate cell adhesion through their disintegrin domain and selective protein cleavage (e.g ...
TEITTINEN, KAISA
core  

Effect of a disintegrin and metalloprotease 33 (ADAM33) gene polymorphisms and smoking in COPD

Egyptian Journal of Chest Disease and Tuberculosis, 2012
Background: COPD is characterized by air flow limitation that is not fully reversed and associated with an influx of neutrophils, macrophages and CD8 T lymphocytes in the airways.
Ayman H. Abd El-Zaher, Hala Nagy, Gihan Farouk, Ahmed Sh. Mohamed, Naglaa F. Ghoname   +4 more
doaj   +1 more source

The High‐Intensity Zone: A Dynamic Inflammatory Hub in Lumbar Disc Degeneration

Orthopaedic Surgery, EarlyView.
The HIZ, a dynamic inflammatory hub in lumbar disc degeneration, links inflammation‐degeneration‐pain; integrating advanced diagnostics and targeted therapies offers precise management for discogenic low back pain. ABSTRACT The lumbar intervertebral disc high‐intensity zone (HIZ), a focal hyperintensity within the annulus fibrosus on T2‐weighted ...
Qi Zhou, Jingyi Cai, Weijian Zhu, Sirui Zhou, Liling Zhou, Yiyao Pei, Gang Wu   +6 more
wiley   +1 more source

Fine Tuning Cell Migration by a Disintegrin and Metalloproteinases

Mediators of Inflammation, 2017
Cell migration is an instrumental process involved in organ development, tissue homeostasis, and various physiological processes and also in numerous pathologies.
D. Dreymueller, K. Theodorou, M. Donners, A. Ludwig   +3 more
doaj   +1 more source

Platelet‐rich plasma (PRP) versus injectable platelet‐rich fibrin (i‐PRF): A systematic review across all fields of medicine

Periodontology 2000, EarlyView.
Abstract This systematic review aimed to evaluate all available evidence across all fields of medicine regarding the comparative effectiveness of platelet‐rich plasma (PRP) versus injectable platelet‐rich fibrin (i‐PRF). A comprehensive search was conducted in PubMed, Scopus, and Web of Science up to September 30, 2024.
Nima Farshidfar, Mohammad Amin Amiri, Nathan E. Estrin, Paras Ahmad, Anton Sculean, Yufeng Zhang, Richard J. Miron   +6 more
wiley   +1 more source

The disintegrin-like domain of the snake venom metalloprotease alternagin inhibits alpha 2 beta 1 integrin-mediated cell adhesion [PDF]

, 2000
The alpha (2)beta (1) integrin is a major collagen receptor that plays an essential role in the adhesion of normal and tumor cells to the extracellular matrix.
Souza, DHF, Ferreira, L. L., Selistre-de-Araujo, H. S., Niewiarowski, S., Zingali, R. B., Oliva, MLV, Iemma, MRC, Faria, J. P.   +7 more
core   +1 more source