Results 171 to 180 of about 2,022 (185)
Some of the next articles are maybe not open access.
Correlation of disulfidptosis and periodontitis: New insights and clinical significance
Archives of Oral BiologyThis study aims to investigate and predict the therapeutic agents associated with disulfidptosis in periodontitis.The dataset GSE10334 was downloaded from the Gene Expression Omnibus (GEO) database and used to train a least absolute shrinkage and selection operator (LASSO) regression and support vector machine recursive feature elimination (SVM-RFE ...
Yixin, Fan +10 more
openaire +2 more sources
Journal of Ethnopharmacology
Ulcerative colitis (UC), a recurrent inflammatory bowel disease, continues to challenge effective pharmacologic management. Disulfidptosis, a recently identified form of cell death, appears implicated in the progression of various diseases. Scientific studies have demonstrated that Modified Gegen Qinlian decoction (MGQD) alleviates UC symptoms. However,
Jinke, Huang +3 more
openaire +2 more sources
Ulcerative colitis (UC), a recurrent inflammatory bowel disease, continues to challenge effective pharmacologic management. Disulfidptosis, a recently identified form of cell death, appears implicated in the progression of various diseases. Scientific studies have demonstrated that Modified Gegen Qinlian decoction (MGQD) alleviates UC symptoms. However,
Jinke, Huang +3 more
openaire +2 more sources
Disulfidptosis in cancer: from redox stress to therapeutic strategy
Cancer Gene TherapyDisulfidptosis, a recently identified form of disulfide-dependent cell death, has emerged as a key regulator of cancer progression and therapy resistance. This review examines the molecular mechanisms connecting the redox balance within the tumor microenvironment (TME), outlines its crosstalk with traditional cell death pathways, and highlights its ...
Xinpei Deng +5 more
openaire +2 more sources
Nanomedicine strategies for disulfidptosis activation in SLC7A11-high tumors
Colloids and Surfaces B: BiointerfacesDisulfidptosis is a recently identified form of regulated cell death (RCD) characterized by aberrant disulfide bond accumulation and cytoskeletal collapse under conditions of redox imbalance. SLC7A11-overexpressing tumors are uniquely susceptible to this pathway due to their elevated cystine uptake and dependence on glucose-driven NADPH production for ...
Zhanzheng Ye +6 more
openaire +2 more sources
Disulfidptosis meets antitumour immunity
Nature Cell BiologyQidong Li, Boyi Gan
openaire +2 more sources