Results 221 to 230 of about 1,846,477 (392)

Mechanics-dependent Global Nuclear Eviction and Site-Specific Recruitment of YAP Regulates DNA Damage Responses [PDF]

Shantam Yagnik, Aprotim Mazumder
openalex   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Obesity and cancer: Relevance of DNA damage response. [PDF]

Transl Oncol
Deshmukh B, Ajay AK, Bhat MK.
europepmc   +1 more source

SOG1‐dependent NAC103 modulates the DNA damage response as a transcriptional regulator in Arabidopsis [PDF]

, 2018
Tae Ho Ryu, Young Sam Go, Seung Hee Choi, Jeong‐Il Kim, Byung Yeoup Chung, Jin‐Hong Kim, Jin‐Hong Kim, Jin‐Hong Kim   +7 more
openalex   +1 more source

Sexually dimorphic DNA damage responses and mutation avoidance in the mouse germline [PDF]

, 2020
Jordana C. Bloom, John C. Schimenti
openalex   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Implications of DNA damage response and immunotherapy in tumor therapy. [PDF]

Cell Commun Signal
Li W, Li B, Cai C, Chen J, Li Y, Liang R, Zhao J.   +6 more
europepmc   +1 more source

Author response: The transcription factors TFE3 and TFEB amplify p53 dependent transcriptional programs in response to DNA damage

, 2018
Owen A. Brady, Eutteum Jeong, José A. Martina, Mehdi Pirooznia, Ilker Tunc, Rosa Puertollano   +5 more
openalex   +1 more source

Differential and collaborative actions of Rad51 paralog proteins in cellular response to DNA damage [PDF]

, 2005
Yasukazu Yonetani
openalex   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source