Results 281 to 290 of about 1,846,477 (392)

Distinct roles of ATR and DNA‐PKcs in triggering DNA damage responses in ATM‐deficient cells [PDF]

, 2009
Nozomi Tomimatsu, Bipasha Mukherjee, Sandeep Burma   +2 more
openalex   +1 more source

The DNA damage response induces inflammation and senescence by inhibiting autophagy of GATA4

Science, 2015
Chanhee Kang, Qikai Xu, Timothy D. Martin, Mamie Z. Li, M. Demaria, Liviu Aron, Tao Lu, B. Yankner, J. Campisi, S. Elledge   +9 more
semanticscholar   +1 more source

Shared Genetic Effects and Antagonistic Pleiotropy Between Multiple Sclerosis and Common Cancers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epidemiologic studies have reported inconsistent altered cancer risk in individuals with multiple sclerosis (MS). Factors such as immune dysregulation, comorbidities, and disease‐modifying therapies may contribute to this variability.
Asli Buyukkurt, Marius Ygonia, Ali Manouchehrinia, Philippe Lefrançois, Ingrid Kockum, Adil Harroud   +5 more
wiley   +1 more source

DNA Damage Response and Redox Status in the Resistance of Multiple Myeloma Cells to Genotoxic Treatment. [PDF]

Int J Mol Sci
Malamos P, Papanikolaou C, Deligianni E, Mavroeidi D, Koutoulogenis K, Gavriatopoulou M, Terpos E, Souliotis VL.   +7 more
europepmc   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Methionine deficiency causes spermatogonial apoptosis via oxidative stress and DNA damage response pathway. [PDF]

Biol Res
Wang W, Ruan Y, Ting G.
europepmc   +1 more source

The DNA damage response: ten years after.

Molecules and Cells, 2007
J. Harper, S. Elledge, S. Elledge, S. Elledge   +3 more
semanticscholar   +1 more source

Neuroinflammation in GAD65 Antibody‐Associated Epilepsy Measured Using [18F]DPA‐714 PET/MRI

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The timing for initiating immunotherapy in patients with glutamic acid decarboxylase 65 (GAD65) antibody‐associated epilepsy is a challenge. We used the translocator protein radioligand [18F]DPA‐714 and PET to evaluate brain microglial activation.
Jingjing Chen, Yuying Zhang, Heyu Zhang, Jinming Zhang, Ningning Wang, Xintong Guo, Yicong Liu, Yue Liu, Xiangsong Zhang, Ziyi Chen, Guanzhong Ni   +10 more
wiley   +1 more source

Anti-Müllerian Hormone Ameliorates Uterine DNA Damage Response and Prevents Pregnancy Complications in Doxorubicin-Treated Mice†. [PDF]

Biol Reprod
Nguyen NMP, Mermin-Bunnell AM, Mattos K, Cleverdon J, Kano M, Chauvin M, Godin P, Kashiwagi A, Duong T, Nagykery N, Donahoe PK, Meinsohn MC, Pepin D.   +12 more
europepmc   +1 more source

Reduction in Renal Relapse and Preservation of Long‐Term Kidney Function After Lupus Low Disease Activity in Patients With Lupus Nephritis

Arthritis Care &Research, EarlyView.
Objective Lupus low disease activity state (LLDAS) is a validated treatment target in systemic lupus erythematosus (SLE), but limited studies have explored the role of LLDAS in lupus nephritis (LN). This study aims to investigate the frequency and predictors of LLDAS attainment and its benefit on LN relapse and renal function preservation in patients ...
Chak Kwan Cheung, Desmond Y. H. Yap, Ka Lai Lee, Philip H. Li, Iris Y. K. Tang, Chak Sing Lau, Shirley C. W. Chan   +6 more
wiley   +1 more source