Results 201 to 210 of about 2,102,008 (248)
Raman spectroscopy successfully identified antibiotic‐resistant Gram‐negative strains. Resistant strains of four bacterial species were discriminated from sensitive ones with 99.1% accuracy using PLS regression. The method allows for rapid, label‐free detection of antibiotic resistance.
Fernanda Sant Ana de Siqueira e Oliveira +3 more
wiley +1 more source
A first-principles quantitative framework for how cohesin regulators shape chromatin loop extrusion. [PDF]
Huang Z, Liu X, Ding J.
europepmc +1 more source
ABSTRACTBackgroundLow back pain remains the leading cause of disability worldwide, with intervertebral disc degeneration representing a major biological contributor. Although cell‐based therapies have shown promise in preclinical models, clinical translation has yielded modest and inconsistent outcomes.
Tynhinane Hamidouche +9 more
wiley +1 more source
High-resolution chromatin mapping reveals that CTCF anchors meiotic loops to the chromosome axis. [PDF]
Cheng G +7 more
europepmc +1 more source
Next‐Generation Pluronic Micelles for Advanced Drug Delivery Application
The present review provides a comprehensive overview of Pluronic‐based micelles for advanced drug and gene delivery. It highlights their structure, classification, synthesis, self‐assembly, and functionalization, as well as their biocompatibility and stimuli‐responsive properties.
Manoj Gundeti +6 more
wiley +1 more source
SMC complex unidirectionally translocates DNA by coupling segment capture with an asymmetric kleisin path. [PDF]
Yamauchi M +3 more
europepmc +1 more source
Tissue‐Resident Macrophage in Inflammation and Cancer
Opposing macrophage functions in inflammation and cancer converge on shared mechanistic nodes, informing cross‐disease therapeutic strategies. ABSTRACT Tissue‐resident macrophages (TRMs) are long‐lived immune cells strategically distributed across organs, where their functional plasticity enables both homeostatic maintenance and pathological ...
Siyuan Huang +13 more
wiley +1 more source
Cohesin acetylation and ATPase activity control cohesion and loop architecture through distinct mechanisms. [PDF]
Costantino L +7 more
europepmc +1 more source
Abstract Background Non‐motor symptoms, especially autonomic dysfunction, are major contributors to disability and decreased quality of life in Parkinson's disease (PD). Despite being common and having a wide range of clinical facets, exocrine gland dysfunction is still not well recognized and managed.
Renato P. Munhoz +2 more
wiley +1 more source
Wiz regulates clustered protocadherin genes by restricting CTCF/cohesin loop extrusion in a genomic-distance biased manner. [PDF]
Li T, Li J, Wang L, Huang H, Wu Q.
europepmc +1 more source

