Highlight DNA Methylation Biomarkers in Different Cancer Type for Drug Designing [PDF]
Journal of Epigenetics, 2022 Recently the study of epigenetics is related to diverse processes such as chromatin structure, tumorigenesis, transcriptional regulation, and genome integrity. Epigenetics defect is one of a new area of cancer detection.
Samina Gul, Tang Wenru
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Transcriptional repressive H3K9 and H3K27 methylations contribute to DNMT1-mediated DNA methylation recovery. [PDF]
PLoS ONE, 2011 DNA methylation and histone modifications are two major epigenetic events regulating gene expression and chromatin structure, and their alterations are linked to human carcinogenesis.
Chun-Ming Wong +5 more
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SETDB1 is involved in postembryonic DNA methylation and gene silencing in Drosophila. [PDF]
PLoS ONE, 2010 DNA methylation is fundamental for the stability and activity of genomes. Drosophila melanogaster and vertebrates establish a global DNA methylation pattern of their genome during early embryogenesis. Large-scale analyses of DNA methylation patterns have
Dawei Gou +7 more
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Influence of genetic background and tissue types on global DNA methylation patterns. [PDF]
PLoS ONE, 2010 Recent studies have shown a genetic influence on gene expression variation, chromatin, and DNA methylation. However, the effects of genetic background and tissue types on DNA methylation at the genome-wide level have not been characterized extensively ...
Howard H Yang +7 more
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Investigating the epigenetic effects of a prototype smoke-derived carcinogen in human cells. [PDF]
PLoS ONE, 2010 Global loss of DNA methylation and locus/gene-specific gain of DNA methylation are two distinct hallmarks of carcinogenesis. Aberrant DNA methylation is implicated in smoking-related lung cancer.
Stella Tommasi +5 more
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Comprehensive analysis of preeclampsia-associated DNA methylation in the placenta. [PDF]
PLoS ONE, 2014 A small number of recent reports have suggested that altered placental DNA methylation may be associated with early onset preeclampsia. It is important that further studies be undertaken to confirm and develop these findings.
Tianjiao Chu +6 more
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Genetic and DNA methylation changes in cotton (Gossypium) genotypes and tissues. [PDF]
PLoS ONE, 2014 In plants, epigenetic regulation is important in normal development and in modulating some agronomic traits. The potential contribution of DNA methylation mediated gene regulation to phenotypic diversity and development in cotton was investigated between
Kenji Osabe +7 more
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The Role of Host Cell DNA Methylation in the Immune Response to Bacterial Infection
Frontiers in Immunology, 2021 Host cells undergo complex transcriptional reprogramming upon infection. Epigenetic changes play a key role in the immune response to bacteria, among which DNA modifications that include methylation have received much attention in recent years.
Wanhai Qin +4 more
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Genome-wide profiling of DNA methylation and gene expression in Crassostrea gigas male gametes
Frontiers in Physiology, 2014 DNA methylation patterns and functions are variable across invertebrate taxa. In order to provide a better understanding of DNA methylation in the Pacific oyster (Crassostrea gigas), we characterized the genome-wide DNA methylation profile in male gamete
Claire E. Olson, Steven B. Roberts
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Evaluation of the usefulness of saliva for DNA methylation analysis in cohort studies
Neuropsychopharmacology Reports, 2019 Introduction Epigenetic information such as DNA methylation is a useful biomarker that reflects complex gene‐environmental interaction. Peripheral tissues such as blood and saliva are commonly collected as the source of genomic DNA in cohort studies ...
Yui Murata +10 more
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