Feasibility of DNA Methylation Age as a Biomarker of Symptoms and Resilience among Cancer Survivors with Multiple Chronic Conditions [PDF]
Biomedicines, 2023 This study aims to examine the feasibility of DNA methylation age as a biomarker for symptoms and resilience in cancer survivors with multiple chronic conditions (MCCs).
Nada Lukkahatai +9 more
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Healthy lifestyle, DNA methylation age acceleration, and incident risk of coronary heart disease [PDF]
Clinical Epigenetics, 2023 Background DNA methylation clocks emerged as a tool to determine biological aging and have been related to mortality and age-related diseases. Little is known about the association of DNA methylation age (DNAm age) with coronary heart disease (CHD ...
Jiahui Si +19 more
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Cross-Platform Application of DNA Methylation Age Estimation Model in Eastern Chinese Han Population [PDF]
Fayixue Zazhi, 2023 Objective To evaluate the forensic application value of an age estimation model based on DNA methylation in eastern Chinese Han population， and to provide a theoretical basis for exploring age estimation models suitable for different detection platforms.
Zi-wei WANG, Cheng-tao LI, Xi-ling LIU
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Modeling Methods and Influencing Factors for Age Estimation Based on DNA Methylation [PDF]
Fayixue Zazhi, 2023 Age estimation based on tissues or body fluids is an important task in forensic science. The changes of DNA methylation status with age have certain rules, which can be used to estimate the age of the individuals.
Yi-hang HUANG, Wei-bo LIANG, Hui JIAN, Sheng-qiu QU
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Progress in age estimation based on DNA methylation
Journal of Forensic Science and Medicine, 2023 In forensic practice, the age of suspects or victims is crucial information that aids in the resolution of cases. In recent years, age estimation based on DNA methylation has gained significant attention in forensic science.
Yihang Huang +4 more
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Frontiers in Genetics, 2023 Purpose: Aging is one of the most important risk factors for a number of human diseases. Epigenetic alterations, including changes in DNA methylation patterns, have been reported to be one of the hallmarks of aging. Being a malleable process, the role of
Anshika Kaushik +4 more
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Predictors and consequences of global DNA methylation in cord blood and at three years. [PDF]
PLoS ONE, 2013 DNA methylation changes have been implicated in many common chronic diseases leading to the hypothesis that environmental and age-related DNA methylation changes within individuals are involved in disease etiology.
Julie B Herbstman +8 more
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The relationship of DNA methylation with age, gender and genotype in twins and healthy controls. [PDF]
PLoS ONE, 2009 Cytosine-5 methylation within CpG dinucleotides is a potentially important mechanism of epigenetic influence on human traits and disease. In addition to influences of age and gender, genetic control of DNA methylation levels has recently been described ...
Marco P Boks +7 more
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Epigenetics, 2021 Chronic kidney disease (CKD) related cardiovascular disease (CVD) is characterized by vascular remodelling with well-established structural and functional changes in the vascular wall such as arterial stiffness, matrix deposition, and calcification ...
Athina Dritsoula +10 more
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Local CpG density affects the trajectory and variance of age-associated DNA methylation changes
Genome Biology, 2022 Background DNA methylation is an epigenetic mark associated with the repression of gene promoters. Its pattern in the genome is disrupted with age and these changes can be used to statistically predict age with epigenetic clocks.
Jonathan Higham +16 more
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