Results 41 to 50 of about 267,722 (305)

Evaluation of age-associated DNA methylation markers in colorectal cancer of Thai population

open access: yesForensic Science International: Reports, 2022
Age prediction using biomarkers has been extensively studied which can be helpful in forensic and health sciences. DNA methylation has been demonstrated to be the most promising molecular biomarkers for age prediction in forensic sciences, and many ...
Tanaporn Lucknuch, Pairoa Praihirunkit
doaj   +1 more source

Socioeconomic Position and DNA Methylation Age Acceleration across the Lifecourse. [PDF]

open access: yes, 2018
Accelerated DNA methylation age is linked to all-cause mortality and environmental factors, but studies of associations with socioeconomic position are limited.
Amanda Hughes   +39 more
core   +2 more sources

Klotho Gene, Aging and DNA Methylation

open access: yesJournal of Marmara University Institute of Health Sciences, 2014
Doğal bir süreç olan yaşlanma, zamanın akışı içerisinde canlı organizmada görülen anatomik ve fizyolojik değişiklikler olarak kendini gösterir. Yaşlanma sürecinde hem çevresel hem de genetik faktörler etkili olur. Genetik faktörler arasında farklı metabolik yolakları kontrol eden birçok gen yer alır.
ÇAĞLAYAN, Elif, TURAN, Kadir
openaire   +2 more sources

DNA methylation controls hematopoietic stem cell aging

open access: yesNature Aging, 2023
Epigenome deregulation is considered a hallmark of aging; however, the function of the alteration of DNA methylation in aged tissues is a long-standing question. Hong and colleagues reveal the mechanism and consequences of DNA methylation loss at heterochromatin regions in aged hematopoietic stem cells.
Krepelova, A, Neri, F
openaire   +2 more sources

Maternal BMI as a predictor of methylation of obesity-related genes in saliva samples from preschool-age Hispanic children at-risk for obesity. [PDF]

open access: yes, 2017
BackgroundThe study of epigenetic processes and mechanisms present a dynamic approach to assess complex individual variation in obesity susceptibility. However, few studies have examined epigenetic patterns in preschool-age children at-risk for obesity ...
Barkin, Shari L   +4 more
core   +2 more sources

DNA Methylation Biomarkers in Aging and Age-Related Diseases [PDF]

open access: yesFrontiers in Genetics, 2020
Recent research efforts provided compelling evidence of genome-wide DNA methylation alterations in aging and age-related disease. It is currently well established that DNA methylation biomarkers can determine biological age of any tissue across the entire human lifespan, even during development.
Yasmeen Salameh   +2 more
openaire   +3 more sources

Epigenetic aging in cows is accelerated by milk production

open access: yesEpigenetics, 2023
DNA methylation has proven to be the most promising age-predictive biomarker in mammals resulting in the emergence of ‘epigenetic clocks’ that describe the relationship between methylation levels and age. Using Targeted bisulfite Sequencing, we evaluated
Prashansa Ratan   +6 more
doaj   +1 more source

From early stress to 12-month development in very preterm infants: Preliminary findings on epigenetic mechanisms and brain growth [PDF]

open access: yes, 2018
Very preterm (VPT) infants admitted to Neonatal Intensive Care Unit (NICU) are at risk for altered brain growth and less-than-optimal socio-emotional development.
Borgatti, R.   +13 more
core   +1 more source

Sex differences in DNA methylation assessed by 450 K BeadChip in newborns. [PDF]

open access: yes, 2015
BackgroundDNA methylation is an important epigenetic mark that can potentially link early life exposures to adverse health outcomes later in life.
Barcellos, Lisa   +5 more
core   +1 more source

DNA Methylation Modulates Aging Process in Adipocytes

open access: yesAging and disease, 2022
Aging has been recognized to be a highly complex biological health problem with a high risk of chronic diseases, including type 2 diabetes, atherosclerosis, chronic bronchitis or emphysema, cancer and Alzheimer's disease. Particularly, age-related turnover in adipose tissue is a major contributor to metabolic syndromes and shortened lifespan ...
Xie, Hao   +10 more
openaire   +2 more sources

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