Evaluation of age-associated DNA methylation markers in colorectal cancer of Thai population
Age prediction using biomarkers has been extensively studied which can be helpful in forensic and health sciences. DNA methylation has been demonstrated to be the most promising molecular biomarkers for age prediction in forensic sciences, and many ...
Tanaporn Lucknuch, Pairoa Praihirunkit
doaj +1 more source
Socioeconomic Position and DNA Methylation Age Acceleration across the Lifecourse. [PDF]
Accelerated DNA methylation age is linked to all-cause mortality and environmental factors, but studies of associations with socioeconomic position are limited.
Amanda Hughes +39 more
core +2 more sources
Klotho Gene, Aging and DNA Methylation
Doğal bir süreç olan yaşlanma, zamanın akışı içerisinde canlı organizmada görülen anatomik ve fizyolojik değişiklikler olarak kendini gösterir. Yaşlanma sürecinde hem çevresel hem de genetik faktörler etkili olur. Genetik faktörler arasında farklı metabolik yolakları kontrol eden birçok gen yer alır.
ÇAĞLAYAN, Elif, TURAN, Kadir
openaire +2 more sources
DNA methylation controls hematopoietic stem cell aging
Epigenome deregulation is considered a hallmark of aging; however, the function of the alteration of DNA methylation in aged tissues is a long-standing question. Hong and colleagues reveal the mechanism and consequences of DNA methylation loss at heterochromatin regions in aged hematopoietic stem cells.
Krepelova, A, Neri, F
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Maternal BMI as a predictor of methylation of obesity-related genes in saliva samples from preschool-age Hispanic children at-risk for obesity. [PDF]
BackgroundThe study of epigenetic processes and mechanisms present a dynamic approach to assess complex individual variation in obesity susceptibility. However, few studies have examined epigenetic patterns in preschool-age children at-risk for obesity ...
Barkin, Shari L +4 more
core +2 more sources
DNA Methylation Biomarkers in Aging and Age-Related Diseases [PDF]
Recent research efforts provided compelling evidence of genome-wide DNA methylation alterations in aging and age-related disease. It is currently well established that DNA methylation biomarkers can determine biological age of any tissue across the entire human lifespan, even during development.
Yasmeen Salameh +2 more
openaire +3 more sources
Epigenetic aging in cows is accelerated by milk production
DNA methylation has proven to be the most promising age-predictive biomarker in mammals resulting in the emergence of ‘epigenetic clocks’ that describe the relationship between methylation levels and age. Using Targeted bisulfite Sequencing, we evaluated
Prashansa Ratan +6 more
doaj +1 more source
From early stress to 12-month development in very preterm infants: Preliminary findings on epigenetic mechanisms and brain growth [PDF]
Very preterm (VPT) infants admitted to Neonatal Intensive Care Unit (NICU) are at risk for altered brain growth and less-than-optimal socio-emotional development.
Borgatti, R. +13 more
core +1 more source
Sex differences in DNA methylation assessed by 450 K BeadChip in newborns. [PDF]
BackgroundDNA methylation is an important epigenetic mark that can potentially link early life exposures to adverse health outcomes later in life.
Barcellos, Lisa +5 more
core +1 more source
DNA Methylation Modulates Aging Process in Adipocytes
Aging has been recognized to be a highly complex biological health problem with a high risk of chronic diseases, including type 2 diabetes, atherosclerosis, chronic bronchitis or emphysema, cancer and Alzheimer's disease. Particularly, age-related turnover in adipose tissue is a major contributor to metabolic syndromes and shortened lifespan ...
Xie, Hao +10 more
openaire +2 more sources

