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DNA Mismatch Repair Protein Interactions on Mismatch‐Containing DNA
The FASEB Journal, 2016Lynch syndrome (LS) is the most common form of hereditary colon cancer. Stemming from the inheritance of mutations in the DNA mismatch repair (MMR) genes, LS increases lifetime risk for colonic and certain extra‐colonic cancers. Unlike sporadic cancers, LS cancers have an average age of onset of 40 years‐old.
Nilse Lene Goncalves Dos Santos +2 more
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DNA Mismatch Repair in Prostate Cancer
Journal of Clinical Oncology, 2013Identification of germline mutations associated with cancer susceptibility has led to the rational development of screening protocols and prevention strategies for patients with heritable syndromes or those at increased risk for developing cancer. As reported in Journal of Clinical Oncology, Raymond et al investigated several generations of a large ...
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DNA repair | DNA Mismatch Repair and the DNA Damage Response
2021Weizhi Xu, Guo-Min Li
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DNA repair | DNA Mismatch Repair in Disease and Aging
2021Peggy Hsieh, Yongliang Zhang
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